Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Karl, Lohner"'
Autor:
Ayse Ön, Djenana Vejzovic, James Jennings, Lena Parigger, Robert A. Cordfunke, Jan Wouter Drijfhout, Karl Lohner, Nermina Malanovic
Publikováno v:
Antibiotics, Vol 12, Iss 7, p 1163 (2023)
OP-145 and SAAP-148, two 24-mer antimicrobial peptides derived from human cathelicidin LL-37, exhibit killing efficacy against both Gram-positive and Gram-negative bacteria at comparable peptide concentrations. However, when it comes to the killing a
Externí odkaz:
https://doaj.org/article/6b4dd8f2c7874557aee2f6e8f7a1acba
Autor:
Enrico F Semeraro, Lisa Marx, Johannes Mandl, Ilse Letofsky-Papst, Claudia Mayrhofer, Moritz PK Frewein, Haden L Scott, Sylvain Prévost, Helmut Bergler, Karl Lohner, Georg Pabst
Publikováno v:
eLife, Vol 11 (2022)
We report the real-time response of Escherichia coli to lactoferricin-derived antimicrobial peptides (AMPs) on length scales bridging microscopic cell sizes to nanoscopic lipid packing using millisecond time-resolved synchrotron small-angle X-ray sca
Externí odkaz:
https://doaj.org/article/75cdca6652d94b5d8588a2a4cb453830
Autor:
Djenana Vejzovic, Paulina Piller, Robert A. Cordfunke, Jan W. Drijfhout, Tobias Eisenberg, Karl Lohner, Nermina Malanovic
Publikováno v:
Biomolecules, Vol 12, Iss 9, p 1252 (2022)
The need for alternative treatment of multi-drug-resistant bacteria led to the increased design of antimicrobial peptides (AMPs). AMPs exhibit a broad antimicrobial spectrum without a distinct preference for a specific species. Thus, their mechanism,
Externí odkaz:
https://doaj.org/article/12c84309b30e4bd588c862651c7b7600
Autor:
Paulina Piller, Heimo Wolinski, Robert A. Cordfunke, Jan Wouter Drijfhout, Sandro Keller, Karl Lohner, Nermina Malanovic
Publikováno v:
Biomolecules, Vol 12, Iss 4, p 523 (2022)
The development of antimicrobial agents against multidrug-resistant bacteria is an important medical challenge. Antimicrobial peptides (AMPs), human cathelicidin LL-37 and its derivative OP-145, possess a potent antimicrobial activity and were under
Externí odkaz:
https://doaj.org/article/46e80550e57d4f48b239ea04b59ff369
Autor:
Malanovic, Ayse Ön, Djenana Vejzovic, James Jennings, Lena Parigger, Robert A. Cordfunke, Jan Wouter Drijfhout, Karl Lohner, Nermina
Publikováno v:
Antibiotics; Volume 12; Issue 7; Pages: 1163
OP-145 and SAAP-148, two 24-mer antimicrobial peptides derived from human cathelicidin LL-37, exhibit killing efficacy against both Gram-positive and Gram-negative bacteria at comparable peptide concentrations. However, when it comes to the killing a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::0996617f29703e975e5503dca8f26bad
Autor:
Anna Huber, Gregor Oemer, Nermina Malanovic, Karl Lohner, Laura Kovács, Willi Salvenmoser, Johannes Zschocke, Markus A. Keller, Florentine Marx
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
The membrane sphingolipid glucosylceramide (GlcCer) plays an important role in fungal fitness and adaptation to most diverse environments. Moreover, reported differences in the structure of GlcCer between fungi, plants and animals render this pathway
Externí odkaz:
https://doaj.org/article/bbc1215baf41473e9caabc97aaa0d20c
Autor:
Christina Wodlej, Sabrina Riedl, Beate Rinner, Regina Leber, Carina Drechsler, Dennis R Voelker, Jae-Yeon Choi, Karl Lohner, Dagmar Zweytick
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0211187 (2019)
R-DIM-P-LF11-322 and DIM-LF11-318, derived from the cationic human host defense peptide lactoferricin show antitumor activity against human melanoma. While R-DIM-P-LF11-322 interacts specifically with cancer cells, the non-specific DIM-LF11-318 exhib
Externí odkaz:
https://doaj.org/article/d41f7d6a7a7542fd95a2a9bdcd0d92aa
Autor:
Ivo Kabelka, Vasil Georgiev, Lisa Marx, Peter Pajtinka, Karl Lohner, Georg Pabst, Rumiana Dimova, Robert Vácha
Publikováno v:
Biophysical Journal
We previously speculated that the synergistically enhanced antimicrobial activity of Magainin 2 and PGLa is related to membrane adhesion, fusion, and further membrane remodelling. Here, we combined computer simulations with time-resolved in vitro flu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1da66d7197a3b8938e09f95a67d68118
https://doi.org/10.1016/j.bpj.2021.12.035
https://doi.org/10.1016/j.bpj.2021.12.035
Autor:
Johannes Mandl, Enrico F. Semeraro, Lisa Marx, Helmut Bergler, Haden L. Scott, Georg Pabst, Karl Lohner, Sylvain Prévost, Moritz P. K. Frewein
Publikováno v:
'Journal of Applied Crystallography ', vol: 54, pages: 473-485 (2021)
A previously reported multi-scale model for (ultra-)small-angle X-ray (USAXS/SAXS) and (very) small-angle neutron scattering (VSANS/SANS) of live Escherichia coli was revised on the basis of compositional/metabolomic and ultrastructural constraints.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a9f370d94d2ea349665271b9c2b2a01
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:57702
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:57702
Autor:
Enrico F. Semeraro, Lionel Porcar, Gerald N. Rechberger, Lisa Marx, Karl Lohner, Moritz P. K. Frewein, Georg Pabst
Publikováno v:
'Faraday Discussions ', vol: 232, pages: 435-447 (2021)
Faraday Discussions
Faraday Discussions
We report on the response of asymmetric lipid membranes composed of palmitoyl oleoyl phosphatidylethanolamine and palmitoyl oleoyl phosphatidylglycerol, to interactions with the frog peptides L18W-PGLa and magainin 2 (MG2a), as well as the lactoferri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6df42022492583d254323476ca6afc
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ILL:31449
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ILL:31449