Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Karl, Hawkins"'
Autor:
Joana A. Moura, Hugh J. Barlow, Shareen H. Doak, Karl Hawkins, Iris Muller, Martin J. D. Clift
Publikováno v:
Journal of Functional Biomaterials, Vol 15, Iss 9, p 265 (2024)
A hallmark of angiogenesis is the sprouting of endothelial cells. To replicate this event in vitro, biomaterial approaches can play an essential role in promoting cell migration. To study the capacity of a scaffold of fibrin (fibrinogen:thrombin mix)
Externí odkaz:
https://doaj.org/article/46b8d699eee14c9b8f4d8c196c06b0ec
Autor:
Lee Butcher, Jun-Cezar Zaldua, Jose A. Carnicero, Karl Hawkins, Janet Whitley, Rangaswamy Mothukuri, Phillip A. Evans, Keith Morris, Suresh Pillai, Jorge D. Erusalimsky
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-7 (2022)
Abstract Blood levels of the soluble receptor for advanced glycation end-products (sRAGE) are acutely elevated during the host inflammatory response to infection and predict mortality in COVID-19. However, the prognostic performance of this biomarker
Externí odkaz:
https://doaj.org/article/5b1bb484d82d41ada87a19bd1f166742
Autor:
Matthew J. Lawrence PhD, Daniel R. Obaid PhD, Ahmed Sabra PhD, Janet Whitley BA, Rhianwen Quarry MBBch, Suresh Pillai MSc, Alexander J. Chase PhD, David Smith MD, Phylip R. Williams PhD, Karl Hawkins PhD, Roger H.K. Morris PhD, Phillip A. Evans MD
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 29 (2023)
Background Unfavourable clot microstructure is associated with adverse outcomes in ST elevation myocardial infarction (STEMI). We investigated the effect of comorbidities and anti-platelet treatment on clot microstructure in STEMI patients using frac
Externí odkaz:
https://doaj.org/article/8eb367a08997456997c917b8e19aaa48
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Purpose: Bioprinting is becoming an increasingly popular platform technology for engineering a variety of tissue types. Our aim was to identify biomaterials that have been found to be suitable for extrusion 3D bioprinting, outline their biomechanical
Externí odkaz:
https://doaj.org/article/fe48abcf2c8a4808bec11819aadbd85f
Autor:
Oliver Watson, Suresh Pillai, Matthew Howard, Jun-Cezar Zaldua, Janet Whitley, Brian Burgess, Matthew Lawrence, Karl Hawkins, Keith Morris, Phillip Adrian Evans
Publikováno v:
Clinical hemorheology and microcirculation. 82(2)
BACKGROUND: A significant degree of mortality and morbidity in Covid-19 is due to thromboembolic disease. Coagulopathy has been well described in critically unwell patients on ICU. There is less clear evidence regarding these changes at the time of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bbd0f808eec90a0dbf8f3d47a1ad51a
https://pubmed.ncbi.nlm.nih.gov/35694917
https://pubmed.ncbi.nlm.nih.gov/35694917
Autor:
Oliver Watson, Jun-Cezar Zaldua, Suresh Pillai, Janet Whitley, Matthew Howard, Matthew Lawrence, Karl Hawkins, Keith Morris, Phillip Adrian Evans
BACKGROUND: A significant degree of mortality and morbidity in Covid-19 is through thromboembolic complications, only partially mitigated by anticoagulant therapy. Reliable markers of infection severity are not fully established. OBJECTIVES: This stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f148615f131bf240edb6ca75d67b00b
https://cronfa.swan.ac.uk/Record/cronfa63235
https://cronfa.swan.ac.uk/Record/cronfa63235
Autor:
Karl Hawkins, Keith Morris, Phillip A. Evans, K Power, C Johns, S Pillai, R. L. Williams, Vanessa Evans, Matthew Lawrence, Janet Whitley
BACKGROUND: The acute vascular disease deep vein thrombosis (DVT) requires oral anticoagulants to prevent progression. Monitoring therapeutic efficacy of direct oral anticoagulants (DOAC), including rivaroxaban, is problematic as no reliable test is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8655fa7da8635c91ffa8c1a574deb67b
https://cronfa.swan.ac.uk/Record/cronfa56606/Download/56606__19665__32820538f6b540a4afc79213a019fa82.pdf
https://cronfa.swan.ac.uk/Record/cronfa56606/Download/56606__19665__32820538f6b540a4afc79213a019fa82.pdf
Publikováno v:
Frontiers in Bioengineering and Biotechnology
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Purpose: Bioprinting is becoming an increasingly popular platform technology for engineering a variety of tissue types. Our aim was to identify biomaterials that have been found to be suitable for extrusion 3D bioprinting, outline their biomechanical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4234c34b0dd3ef46cc346448cc874593
https://doi.org/10.3389/fbioe.2021.616753
https://doi.org/10.3389/fbioe.2021.616753
Autor:
Gareth R Davies, Gavin M Mills, Matthew Lawrence, Ceri Battle, Keith Morris, Karl Hawkins, Phylip Rhodri Williams, Simon Davidson, Dafydd Thomas, Phillip Adrian Evans
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108589 (2014)
OBJECTIVE: To assess the prognostic and diagnostic value of whole blood impedance aggregometry in patients with sepsis and SIRS and to compare with whole blood parameters (platelet count, haemoglobin, haematocrit and white cell count). METHODS: We pe
Externí odkaz:
https://doaj.org/article/7b3558993ca14bb6ac224a79b0445839
Autor:
John W. Weisel, M. Rowan Brown, Lubica Rauova, Bethan R. Thomas, P. Rhodri Williams, Karl Hawkins, Nafiseh Badiei, Rebecca J. Hambly, Catherine A. Thornton
Publikováno v:
Thrombosis research. 193
INTRODUCTION Thrombosis is a severe and frequent complication of heparin-induced thrombocytopenia (HIT). However, there is currently no knowledge of the effects of HIT-like antibodies on the resulting microstructure of the formed clot, despite such i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49de04e29d822ff02dd7940ff4c452ae
https://pubmed.ncbi.nlm.nih.gov/32505081
https://pubmed.ncbi.nlm.nih.gov/32505081