Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Kariyappa Ajay Kumar"'
Autor:
Karthik Kumara, Malledevarapura Gurumurthy Prabhudeva, Channa Basappa Vagish, Hamse Kameshwar Vivek, Kuriya Madavu Lokanatha Rai, Neratur Krishnappagowda Lokanath, Kariyappa Ajay Kumar
Publikováno v:
Heliyon, Vol 7, Iss 7, Pp e07592- (2021)
In a sustained search for novel and effective antioxidants, a potential therapeutic leads against renal, and neurological disorders. Amongst the heterocycles, pyrazole and their derivatives have been extensively studied for their biological potencies
Externí odkaz:
https://doaj.org/article/95cf2690458d4e02a3d6fa8aa4dbe622
Publikováno v:
Current Chemistry Letters, Vol 7, Iss 3, Pp 73-80 (2018)
The current study presents the synthesis of thiophene-appended pyrazoles through 3+2 annulations of chalcones 3(a-g)with aryl hydrazine hydrochlorides 4(a-d) in acetic acid (30%) under reflux conditions produced the thiophene-pyrazole hybrids 5(a-g)
Externí odkaz:
https://doaj.org/article/142bb712d1f14266853cfd81510f2489
Autor:
Channa Basappa, Vagish, Hamse Kameshwar, Vivek, Kumara, Karthik, Achutha, Dileep Kumar, Neratur Krishnappagowda, Lokanath, Kariyappa, Ajay Kumar
Publikováno v:
In Heliyon October 2020 6(10)
Autor:
C.B. Vagish, Karthik Kumara, H. K. Vivek, Neratur Krishnappagowda Lokanath, N. Renuka, Achutha Dileep Kumar, Kariyappa Ajay Kumar
Publikováno v:
Journal of the Iranian Chemical Society. 18:479-493
Oxidative stress is an important cause of neurogenerative diseases; treatment with a reliable antioxidant with no side effects is a potential tool to overcome with such diseases. The aim of this study is to explore new and effective antioxidants and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23d8794b39056d3e4431e116b5b87fc3
https://doi.org/10.1007/s13738-020-02042-6
https://doi.org/10.1007/s13738-020-02042-6
Akademický článek
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Akademický článek
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Autor:
Karthik Kumara, Achutha Dileep Kumar, Srinivasan Bharath, M. G. Prabhudeva, Neratur Krishnappagowda Lokanath, Kariyappa Ajay Kumar
Publikováno v:
Bioorganic Chemistry. 80:444-452
Inflammation-mediated disorders are on the rise and hence, there is an urgent need for the design and synthesis of new anti-inflammatory drugs with higher affinity and specificity for their potential targets. The current study presents an effective a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33808440b7ae094eb077f108a3b58b6f
https://doi.org/10.1016/j.bioorg.2018.06.023
https://doi.org/10.1016/j.bioorg.2018.06.023
Autor:
Kariyappa Ajay Kumar, Mylarappa Ningappa, Neratur Krishnappagowda Lokanath, Karthik Kumara, Achutha Dileep Kumar, M. G. Prabhudeva
Publikováno v:
Research on Chemical Intermediates. 44:6453-6468
Increasing instances of antimicrobial drug resistance and Inflammation-mediated disorders requires the design and synthesis of new small-molecules with higher affinity and specificity for their potential targets to serve as antibiotics or anti-inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a2a5f0c224e21a499f95107d9b978ed
https://doi.org/10.1007/s11164-018-3501-2
https://doi.org/10.1007/s11164-018-3501-2
Publikováno v:
Current Chemistry Letters, Vol 7, Iss 3, Pp 73-80 (2018)
The current study presents the synthesis of thiophene-appended pyrazoles through 3+2 annulations of chalcones 3(a-g)with aryl hydrazine hydrochlorides 4(a-d) in acetic acid (30%) under reflux conditions produced the thiophene-pyrazole hybrids 5(a-g)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::945544d2f491cf3100cb7a73100a80df
https://doi.org/10.5267/j.ccl.2018.8.001
https://doi.org/10.5267/j.ccl.2018.8.001
Autor:
Karthik Kumara, Achutha Dileep Kumar, Bharath Srinivasan, H. K. Vivek, S. Naveen, Kullaiah Byrappa, Kariyappa Ajay Kumar, Neratur Krishnappagowda Lokanath
Publikováno v:
Journal of Molecular Structure. 1235:130271
The present study demonstrate the utility of a reverse ligand similarity based approach to identify potential targets for a new series of synthesized pyrazole carboxamides that shows potent anticancer activities against MCF-7 cells compared to other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a75d847deec2ff96383721b31c482f68
https://doi.org/10.1016/j.molstruc.2021.130271
https://doi.org/10.1016/j.molstruc.2021.130271