Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Karishma K Khetani"'
Autor:
Alex C D Salyer, Giuseppe Caruso, Karishma K Khetani, Lauren M Fox, Subbalakshmi S Malladi, Sunil A David
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149848 (2016)
Small-molecule agonists have been identified for TLR7, TLR8, TLR4 and TLR2 thus far, and chemotypes other than those of canonical ligands are yet to be explored for a number of innate immune receptors. The discovery of novel immunostimulatory molecul
Externí odkaz:
https://doaj.org/article/fac84ee9b507428ca2994eb487d43eb8
Autor:
Toshiyuki Shimizu, Karishma K. Khetani, Luke J. Smith, Umeharu Ohto, Nijunj M. Shukla, Sunil A. David, Giuseppe Caruso, Lauren M. Fox, H. Tanji, Mallesh Beesu, Alex C. D. Salyer
Publikováno v:
Journal of Medicinal Chemistry. 59:3311-3330
Activation of human toll-like receptor-8 (TLR8), expressed in myeloid dendritic cells, monocytes, and monocyte-derived dendritic cells, evokes a distinct cytokine profile which favors the development of Type 1 helper T cells. Part-structures of the 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d064385cb0983f1bb628320027e550c
https://doi.org/10.1021/acs.jmedchem.6b00023
https://doi.org/10.1021/acs.jmedchem.6b00023
Autor:
Mallesh Beesu, Diptesh Sil, Sunil A. David, Umeharu Ohto, Mihiri S. Weerasinghe, Karishma K. Khetani, Giuseppe Caruso, Toshiyuki Shimizu, H. Tanji, Alex C. D. Salyer
Publikováno v:
Journal of Medicinal Chemistry
Human Toll-like receptor 8 (hTLR8) is expressed in myeloid dendritic cells, monocytes, and monocyte-derived dendritic cells. Engagement by TLR8 agonists evokes a distinct cytokine profile which favors the development of type 1 helper T cells. Crystal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8942e63844cd0bb219eaaf9cb9dfd67
https://doi.org/10.1021/acs.jmedchem.5b01087
https://doi.org/10.1021/acs.jmedchem.5b01087
Autor:
Karishma K. Khetani, Lauren M. Fox, Giuseppe Caruso, Alex C. D. Salyer, Sunil A. David, Subbalakshmi S. Malladi
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149848 (2016)
PLoS ONE
PLoS ONE
Small-molecule agonists have been identified for TLR7, TLR8, TLR4 and TLR2 thus far, and chemotypes other than those of canonical ligands are yet to be explored for a number of innate immune receptors. The discovery of novel immunostimulatory molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aef4ff343470d9fea92ebc5090080ba
http://europepmc.org/articles/PMC4769227?pdf=render
http://europepmc.org/articles/PMC4769227?pdf=render
Autor:
Mallesh Beesu, Giuseppe Caruso, Alex C.D. Salyer, Karishma K. Khetani, Diptesh Sil, Mihiri Weerasinghe, Hiromi Tanji, Umeharu Ohto, Toshiyuki Shimizu, Sunil A. David
Publikováno v:
Journal of Medicinal Chemistry; Oct2015, Vol. 58 Issue 19, p7833-7849, 17p