Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Karis A Weih"'
Autor:
Danielle Hunt, Justin E Wilson, Karis A Weih, Satoshi Ishido, Jonathan A Harton, Paul A Roche, James R Drake
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37330 (2012)
Francisella tularensis is a bacterial pathogen that uses host-derived PGE₂ to subvert the host's adaptive immune responses in multiple ways. Francisella-induced PGE₂ acts directly on CD4 T cells to blunt production of IFN-γ. Francisella-induced
Externí odkaz:
https://doaj.org/article/1edc20e6d02f4927a2fcde96ca812dc6
Autor:
Young Ho Suh, Aki Yoshimoto-Furusawa, Karis A Weih, Lino Tessarollo, Katherine W Roche, Susan Mackem, Paul A Roche
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18444 (2011)
SNARE-mediated membrane fusion is a pivotal event for a wide-variety of biological processes. SNAP-25, a neuron-specific SNARE protein, has been well-characterized and mouse embryos lacking Snap25 are viable. However, the phenotype of mice lacking SN
Externí odkaz:
https://doaj.org/article/56e16382f6a64aff903d79046d179b26
Publikováno v:
Journal of Biological Chemistry. 285:41749-41754
The expression of MHC class II (MHC-II) on the surface of antigen-presenting cells, such as dendritic cells (DCs), is tightly regulated during cellular activation. Many cells, including DCs, are activated following stimulation of innate Toll-like rec
Autor:
Karis A. Weih, Oddmund Bakke, Satoshi Ishido, Even Walseng, Berta Bosch, Yohei Matsuki, Paul A. Roche, Kazuyuki Furuta
Publikováno v:
Proceedings of the National Academy of Sciences. 107:20465-20470
The expression and turnover of MHC class II-peptide complexes (pMHC-II) on the surface of dendritic cells (DCs) is essential for their ability to activate CD4 T cells efficiently. The half-life of surface pMHC-II is significantly greater in activated
Publikováno v:
AIDS. 13:751-758
Objective To determine the effects of primary human fetal and adult astrocytes on HIV-1 replication in monocyte-derived macrophages (MDM). Design HIV-1 can infect the brain in the early stage of systemic infection. The HIV-1-associated cognitive/moto
Publikováno v:
Blood. 93:1843-1850
Nitric oxide (NO) plays an important role in normal neural cell function. Dysregulated or overexpression of NO contributes to neurologic damage associated with various pathologies, including human immunodeficiency virus (HIV)-associated neurological
Autor:
Paul A. Roche, Satoshi Ishido, James R. Drake, Jonathan A. Harton, Justin E. Wilson, Danielle Hunt, Karis A. Weih
Publikováno v:
PLoS ONE
Francisella tularensis is a bacterial pathogen that uses host-derived PGE2 to subvert the host's adaptive immune responses in multiple ways. Francisella-induced PGE2 acts directly on CD4 T cells to blunt production of IFN-γ. Francisella-induced PGE2
Autor:
Susan Mackem, Katherine W. Roche, Paul A. Roche, Karis A. Weih, Young Ho Suh, Lino Tessarollo, Aki Yoshimoto-Furusawa
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 3, p e18444 (2011)
PLoS ONE, Vol 6, Iss 3, p e18444 (2011)
SNARE-mediated membrane fusion is a pivotal event for a wide-variety of biological processes. SNAP-25, a neuron-specific SNARE protein, has been well-characterized and mouse embryos lacking Snap25 are viable. However, the phenotype of mice lacking SN
Publikováno v:
The Journal of biological chemistry. 281(36)
CDMP1/GDF5 has not demonstrated biological activity in Xenopus embryos when overexpressed by mRNA injection. We provide biological and biochemical evidence that to become active, the protein requires cleavage by two distinct proteolytic enzymes. We d