Výsledky vyhledávání - "Karine Valliant-Saunders"

Limitations of a Transgenic Breast Cancer Model for Studies Erythropoietin-Induced Tumor Progression

Autor: Chris P. Miller, Karine Valliant-Saunders, Carl Anthony Blau

Publikováno v: Translational Oncology. 3:176-180

Adverse effects of erythropoietin (EPO) on tumor progression and survival were observed in recent phase 3 oncology trials. However, mechanisms remain poorly understood. We tested the effects of exogenous EPO on murine B16F10 melanoma growth in a subc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab91a20a83792762e6b9349c4a6952c
https://doi.org/10.1593/tlo.09304

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Stoichiometric oxidations of σ-bonds: Radical and possible non-radical pathways

Autor: Jasmine R. Bryant, Eric J. Watson, Takao Osako, Justine P. Roth, David A. Hrovat, Elizabeth A. Mader, Karine Valliant-Saunders, Ahmad Dehestani, Wai Han Lam, Brian C. Bales, Ernest R. Davidson, Weston Thatcher Borden, Takashi Matsuo, James M. Mayer

Publikováno v: Journal of Molecular Catalysis A: Chemical. 251:24-33

Many transition metal complexes accomplish or catalyze the oxidation of C H, O H, and other σ-bonds. Under aerobic conditions, metal complexes typically modulate an autoxidation radical chain. In anaerobic reactions, a metal complex can be the react

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::61993b9a51a174b25ddfcffd18971d2c
https://doi.org/10.1016/j.molcata.2006.02.010

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Expanding the scope of WT1- and cyclin A1-specific TCR gene therapy for AML and other cancers

Autor: Rachel Perret, Karine Valliant-Saunders, Jennifer W Cao, Philip D Greenberg

Publikováno v: The Journal of Immunology. 196:143.5-143.5

TCR gene therapy hastens the reproducible generation of tumor-specific T cells from patients, creating a promising avenue for treating hematological and solid tumors. Several hurdles remain to making this a broadly effective modality, including varia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::27ed78f916735aeec0ea510b2525cd70
https://doi.org/10.4049/jimmunol.196.supp.143.5

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Paradoxically increased FOXP3+ T cells in IBD do not preferentially express the isoform of FOXP3 lacking exon 2

Autor: James D. Lord, Steven F. Ziegler, Karine Valliant-Saunders, Richard C. Thirlby, Hejin Hahn

Publikováno v: Digestive diseases and sciences. 57(11)

Forkhead box P3 (FOXP3)+ regulatory T cells (Tregs) are critical for controlling inflammation in the gastrointestinal tract. There is a paradoxical increase of mucosal FOXP3+ T cells in patients with inflammatory bowel disease (IBD). These FOXP3+ cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3f0532b65c9ce198dc0284623808447
https://pubmed.ncbi.nlm.nih.gov/22736020

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Evaluating erythropoietin-associated tumor progression using archival tissues from a phase III clinical trial

Autor: C. Anthony Blau, Joringel F. Kaiser, Michael Henke, Nicole Urban, Karine Valliant-Saunders, Chris P. Miller, Dominik Mattern, Kimberly A. Lowe

Publikováno v: Stem cells (Dayton, Ohio). 27(9)

Despite the prevalence of anemia in cancer, recombinant erythropoietin (Epo) has declined in use because of recent Phase III trials showing more rapid cancer progression and reduced survival in subjects randomized to Epo. Since Epo receptor (EpoR), J

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162a8886cd89435a2eb8639da944168a
https://pubmed.ncbi.nlm.nih.gov/19544471

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Oxidation of tertiary silanes by osmium tetroxide

Autor: Erica Gunn, David A. Hrovat, Karine Valliant-Saunders, G. Robert Shelton, James M. Mayer, Weston Thatcher Borden

Publikováno v: Inorganic chemistry. 46(13)

In the presence of an excess of pyridine ligand L, osmium tetroxide oxidizes tertiary silanes (Et(3)SiH, (i)Pr(3)SiH, Ph(3)SiH, or PhMe(2)SiH) to the corresponding silanols. With L = 4-tert-butylpyridine ((t)Bupy), OsO(4)((t)Bupy) oxidizes Et(3)SiH a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::930181d3ef4328da784fc1c158bbc5ea
https://pubmed.ncbi.nlm.nih.gov/17511445

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