Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Karine Proulx"'
Publikováno v:
Systèmes d'information & management. 24:7-46
Le phenomene du BYOD (Bring Your Own Device, Prenez vos Appareils Personnels) represente une tendance lourde sur le marche du travail. Nombreux sont les employes qui reclament d’utiliser les appareils et logiciels de leur choix : telephones et tabl
Publikováno v:
Diabetes
OBJECTIVE—Evidence links the hypothalamic fatty acid synthase (FAS) pathway to the regulation of food intake and body weight. This includes pharmacological inhibitors that potently reduce feeding and body weight. The mammalian target of rapamycin (
Publikováno v:
Journal of Neuroendocrinology. 17:445-451
Ghrelin is an orexigenic peptide made both in the periphery and in the central nervous system. Relatively little is known about the factors that regulate ghrelin secretion. Because both ghrelin and glucocorticoids are increased during fasting, we hyp
Publikováno v:
Alcoholism: Clinical & Experimental Research. 29:958-964
Background: Alcohol is a caloric compound that can contribute to energy intake. Therefore, peptides that regulate energy balance likely modify the motivation to consume alcohol. Melanin-concentrating hormone (MCH) regulates energy homeostasis and has
Autor:
François Pattou, Barbara Sedgwick, Ruth Gutierrez-Aguilar, Stephen O'Rahilly, Marcella Ma, Hiroko Kawagoe-Takaki, Hélène Choquet, Luc Van Gaal, David Meyre, Philippe Froguel, I. Sadaf Farooqi, Karine Proulx, Wim Van Hul, Sophie Visvikis-Siest, Fritz F. Horber, Giles S.H. Yeo, Beverley Balkau, Debbie Lyon, Vladimir Saudek, Vincent Vatin
Publikováno v:
Diabetes
Diabetes; Vol 59
Diabetes; Vol 59
OBJECTIVE Single nucleotide polymorphisms (SNPs) in intron 1 of fat mass– and obesity-associated gene (FTO) are strongly associated with human adiposity, whereas Fto−/− mice are lean and Fto+/− mice are resistant to diet-induced obesity. We a
Autor:
Christelle Golzio, Tomas Lindahl, Hiroko Kawagoe-Takaki, Laurence Colleaux, Giles S.H. Yeo, Stephen O'Rahilly, I. Sadaf Farooqi, Noman Kadhom, Orit Reish, Philippe Froguel, Heather C. Etchevers, Vladimir Saudek, Sarah Boissel, David Meyre, Florence Molinari, Karine Proulx, Barbara Sedgwick, Arnold Munnich
Publikováno v:
American Journal of Human Genetics
American Journal of Human Genetics, Elsevier (Cell Press), 2009, 85 (1), pp.106-111. ⟨10.1016/j.ajhg.2009.06.002⟩
American Journal of Human Genetics, 2009, 85 (1), pp.106-111. ⟨10.1016/j.ajhg.2009.06.002⟩
American Journal of Human Genetics, Elsevier (Cell Press), 2009, 85 (1), pp.106-111. ⟨10.1016/j.ajhg.2009.06.002⟩
American Journal of Human Genetics, 2009, 85 (1), pp.106-111. ⟨10.1016/j.ajhg.2009.06.002⟩
International audience; FTO is a nuclear protein belonging to the AlkB-related non-haem iron-and 2-oxoglutarate-dependent dioxygenase family. Although polymorphisms within the first intron of the FTO gene have been associated with obesity, the physio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49585ee98fbd98ee0c7ae31f3e7760c0
https://hal.archives-ouvertes.fr/hal-02044723/document
https://hal.archives-ouvertes.fr/hal-02044723/document
Publikováno v:
Gastroenterology. 132(6)
Individual cells must carefully regulate their energy flux to ensure nutrient levels are adequate to maintain normal cellular activity. The same principle holds in multicellular organisms. Thus, for mammals to perform necessary physiological function
Autor:
Stephen C. Woods, George Thomas, Karine Proulx, Randy J. Seeley, Kathi Smith, Sara C. Kozma, Daniela Cota
Publikováno v:
Science (New York, N.Y.). 312(5775)
The mammalian Target of Rapamycin (mTOR) protein is a serine-threonine kinase that regulates cell-cycle progression and growth by sensing changes in energy status. We demonstrated that mTOR signaling plays a role in the brain mechanisms that respond
Autor:
Karine Proulx, Tamara R. Castañeda, Matthias H. Tschöp, Patrick Tso, Randy J. Seeley, Stephen C. Woods, David A. D'Alessio, Daniela Cota
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 289(3)
Oleoylethanolamide (OEA), a lipid synthesized in the intestine, reduces food intake and stimulates lipolysis through peroxisome proliferator-activated receptor-α. OEA also activates transient receptor potential vanilloid type 1 (TRPV1) in vitro. Bec
Autor:
Randy J. Seeley, Karine Proulx
Publikováno v:
The Psychiatric clinics of North America. 28(1)
Obesity is the result of a sustained mismatch in which caloric intake exceeds caloric expenditure. In fact, despite what the growing obesity epidemic might argue, under most circumstances the energy balance equation is regulated with tremendous preci