Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Karine Merienne"'
Autor:
Estelle Schueller, Iris Grgurina, Brigitte Cosquer, Elodie Panzer, Noémie Penaud, Anne Pereira de Vasconcelos, Aline Stéphan, Karine Merienne, Jean-Christophe Cassel, Chantal Mathis, Frédéric Blanc, Olivier Bousiges, Anne-Laurence Boutillier
Publikováno v:
Neurobiology of Disease, Vol 201, Iss , Pp 106676- (2024)
Background: Dementia with Lewy bodies (DLB) is the second most common age-related neurocognitive pathology after Alzheimer's disease. Animal models characterizing this disease are lacking and their development would ameliorate both the understanding
Externí odkaz:
https://doaj.org/article/d3ffd1bc14cc41549b6e377f048019ea
Autor:
Isabel Paiva, Jonathan Seguin, Iris Grgurina, Akash Kumar Singh, Brigitte Cosquer, Damien Plassard, Laura Tzeplaeff, Stephanie Le Gras, Ludovica Cotellessa, Charles Decraene, Johanne Gambi, Rafael Alcala-Vida, Muthusamy Eswaramoorthy, Luc Buée, Jean-Christophe Cassel, Paolo Giacobini, David Blum, Karine Merienne, Tapas K. Kundu, Anne-Laurence Boutillier
Publikováno v:
Neurobiology of Disease, Vol 198, Iss , Pp 106538- (2024)
Aging is the main risk factor of cognitive neurodegenerative diseases such as Alzheimer's disease, with epigenome alterations as a contributing factor. Here, we compared transcriptomic/epigenomic changes in the hippocampus, modified by aging and by t
Externí odkaz:
https://doaj.org/article/f5714d9bc754442fab0e4c7aa97ead64
Autor:
Rafael Alcalá-Vida, Jonathan Seguin, Caroline Lotz, Anne M. Molitor, Ibai Irastorza-Azcarate, Ali Awada, Nezih Karasu, Aurélie Bombardier, Brigitte Cosquer, Jose Luis Gomez Skarmeta, Jean-Christophe Cassel, Anne-Laurence Boutillier, Thomas Sexton, Karine Merienne
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The dynamics of chromatin and transcriptional changes underlying Huntington’s disease remain poorly understood. Here the authors use a Huntington’s mouse model to profile the striatal chromatin landscape, finding that the Huntington’s mutation
Externí odkaz:
https://doaj.org/article/0ec358ea614448bdbbaf8af73cea827a
Publikováno v:
Neurobiology of Disease, Vol 147, Iss , Pp 105155- (2021)
Neurodegenerative diseases, including Huntington’s disease (HD) and Alzheimer's disease (AD), are progressive conditions characterized by selective, disease-dependent loss of neuronal regions and/or subpopulations. Neuronal loss is preceded by a lo
Externí odkaz:
https://doaj.org/article/99235588a36f42d888c8c81382792a8e
Autor:
Snehajyoti Chatterjee, Raphaelle Cassel, Anne Schneider‐Anthony, Karine Merienne, Brigitte Cosquer, Laura Tzeplaeff, Sarmistha Halder Sinha, Manoj Kumar, Piyush Chaturbedy, Muthusamy Eswaramoorthy, Stéphanie Le Gras, Céline Keime, Olivier Bousiges, Patrick Dutar, Petnoi Petsophonsakul, Claire Rampon, Jean‐Christophe Cassel, Luc Buée, David Blum, Tapas K Kundu, Anne‐Laurence Boutillier
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 11, Pp 1-20 (2018)
Abstract Chromatin acetylation, a critical regulator of synaptic plasticity and memory processes, is thought to be altered in neurodegenerative diseases. Here, we demonstrate that spatial memory and plasticity (LTD, dendritic spine formation) deficit
Externí odkaz:
https://doaj.org/article/3e3bcfa696b14836b0aa51926f42e2db
Autor:
Karine Merienne, James Friedman, Masayuki Akimoto, Gretta Abou-Sleymane, Chantal Weber, Anand Swaroop, Yvon Trottier
Publikováno v:
Neurobiology of Disease, Vol 25, Iss 3, Pp 571-581 (2007)
We have approached the role of cellular stress in neurodegenerative diseases caused by polyglutamine expansion (polyQ) in the context of Spinocerebellar ataxia type 7 (SCA7) that includes retinal degeneration. Using the R7E mouse, in which polyQ-atax
Externí odkaz:
https://doaj.org/article/84a51c9b977f4dfcb3cd189c5200a3f8
Autor:
Agathi-Vasiliki Goula, Agnieszka Stys, Jackson P K Chan, Yvon Trottier, Richard Festenstein, Karine Merienne
Publikováno v:
PLoS Genetics, Vol 8, Iss 11, p e1003051 (2012)
The expansion of CAG/CTG repeats is responsible for many diseases, including Huntington's disease (HD) and myotonic dystrophy 1. CAG/CTG expansions are unstable in selective somatic tissues, which accelerates disease progression. The mechanisms under
Externí odkaz:
https://doaj.org/article/ecfbe1ec91fd47e9a12828ff7a688968
Autor:
Agathi-Vassiliki Goula, Brian R Berquist, David M Wilson, Vanessa C Wheeler, Yvon Trottier, Karine Merienne
Publikováno v:
PLoS Genetics, Vol 5, Iss 12, p e1000749 (2009)
Huntington's disease (HD) is a progressive neurodegenerative disorder caused by expansion of an unstable CAG repeat in the coding sequence of the Huntingtin (HTT) gene. Instability affects both germline and somatic cells. Somatic instability increase
Externí odkaz:
https://doaj.org/article/8a28ce4b4c5143fd9aab888f433d8eb9
Autor:
Karine Merienne, Yvon Trottier
Publikováno v:
PLoS Genetics, Vol 5, Iss 8, p e1000593 (2009)
Externí odkaz:
https://doaj.org/article/eb17056e63594b95897733284dbeca4a
Hippocampal Cannabinoid 1 Receptors Are Modulated Following Cocaine Self-administration in Male Rats
Autor:
David De Sa Nogueira, Romain Bourdy, Rafael Alcala-Vida, Dominique Filliol, Virginie Andry, Yannick Goumon, Jean Zwiller, Pascal Romieu, Karine Merienne, Mary C. Olmstead, Katia Befort
Publikováno v:
Molecular Neurobiology
Molecular Neurobiology, 2022, Online ahead of print. ⟨10.1007/s12035-022-02722-9⟩
Molecular Neurobiology, 2022, Online ahead of print. ⟨10.1007/s12035-022-02722-9⟩
International audience; Cocaine addiction is a complex pathology inducing long-term neuroplastic changes that, in turn, contribute to maladaptive behaviors. This behavioral dysregulation is associated with transcriptional reprogramming in brain rewar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::287ad0e0cf8271a1adf8473e3af735da
https://doi.org/10.1007/s12035-022-02722-9
https://doi.org/10.1007/s12035-022-02722-9