Biological Activity of Ectodysplasin A Is Conditioned by Its Collagen and Heparan Sulfate Proteoglycan-binding Domains*

Autor: Laure Willen, Pascal Schneider, Aubry Tardivel, Manuel Favre, Lee Kim Swee, Stéphane Demotz, Marja L. Mikkola, Karine Ingold-Salamin, Olivier Gaide

Publikováno v: J Biol Chem
Journal of Biological Chemistry, Vol. 284, No 40 (2009) pp. 27567-27576
Journal of Biological Chemistry, vol. 284, no. 40, pp. 27567-27576

Mutations in the TNF family ligand EDA1 cause X-linked hypohidrotic ectodermal dysplasia (XLHED), a condition characterized by defective development of skin appendages. The EDA1 protein displays a proteolytic processing site responsible for its conve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::068d6b13c26388b5d6b70474d33524c2
https://europepmc.org/articles/PMC2785685/