Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Karine Houde"'
Autor:
Cindy Buonomano, Yvan Guindon, Daniel Chapdelaine, François Godin, Jacques Rodrigue, Karine Houde, Thao Trinh, Martin Duplessis, André Boutros
Publikováno v:
Org. Chem. Front.. 1:974-982
Reported herein is the synthesis of all possible stereotriad propionates derived from L-lactic acid and L-alanine. The approach is based on a stereocontrolled Mukaiyama aldol reaction followed by a free radical-mediated hydrogen transfer, for which t
Publikováno v:
ChemInform. 42
A general reaction for the synthesis of target compounds (II) is developed through acid-mediated cyclization of arylaminotriazines (I).
Autor:
Brigitte Grouix, Boulos Zacharie, Shaun D. Abbott, Dannyck Gaudreau, Jean-Simon Duceppe, Marie-Eve Fafard, Abdallah Ezzitouni, Lyne Gagnon, François Sarra-Bournet, Natalie St-Amant, Caroline Lauzon, Nancie Moreau, Valérie Perron, Alan D. Cameron, Christopher Penney, Nicole Wilb, Jean-François Bienvenu, André Doucet, Michel Asselin, Daniel Fortin, Karine Houde, Josée Cloutier
Publikováno v:
Journal of medicinal chemistry. 53(3)
A first-in-class series of low molecular weight trisubstituted triazines were synthesized and evaluated for their ability to mimic protein A binding to human IgG antibody. The structure-activity relationship (SAR) demonstrates that the 1,3-phenylened
Autor:
Kathleen M. Metters, Deborah Slipetz, Nicolas Lachance, Marc Labelle, Danielle Denis, Chi-Chung Chan, Michel Gallant, Robert Zamboni, Sonia Lamontagne, Gillian Greig, Yves Gareau, Nicole Sawyer, Nathalie Tremblay, Helene Juteau, Karine Houde, Chun Li, Marie-Claude Carrière, Nathalie Chauret, Robert Gordon, Michel Belley
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(21)
Two different series of very potent and selective EP(3) antagonists have been reported: a novel series of ortho-substituted cinnamic acids [Belley, M., Gallant, M., Roy, B., Houde, K., Lachance, N., Labelle, M., Trimble, L., Chauret, N., Li, C., Sawy
Autor:
Chun Li, Nicolas Lachance, Gillian Greig, Michel Gallant, Chi-Chung Chan, Sonia Lamontagne, Nicole Sawyer, Danielle Denis, Deborah Slipetz, Laird A. Trimble, Marc Labelle, Marie-Claude Carrière, R. Gordon, Michel Belley, Kathleen M. Metters, Nathalie Chauret, Bruno Roy, Robert Zamboni, Karine Houde, Nathalie Tremblay
Publikováno v:
Bioorganicmedicinal chemistry letters. 15(3)
A series of novel ortho -substituted cinnamic acids have been synthesized, and their binding activity and selectivity on the four prostaglandin E 2 receptors evaluated. Many of them are very potent and selective EP 3 antagonists ( K i 3–10 nM), whi
Autor:
Karine Houde, Brigitte Guérin, Mohammed Bencheqroun, Yvan Guindon, Michel Prévost, Benoit Daoust, Benoit Cardinal-David, Landry Serge
Publikováno v:
Journal of the American Chemical Society. 123(35)
Reported herein is a strategy employing a Mukaiyama reaction in tandem with a hydrogen transfer reaction for the elaboration of propionate motifs. The nature of the protecting groups on the chiral beta-alkoxy aldehyde and the type of Lewis acid used
Autor:
Benoit Cardinal-David, Yvan Guindon, Landry Serge, and Mohammed Bencheqroun, Brigitte Guérin, Benoit Daoust, Karine Houde, Michel Prévost
Publikováno v:
Journal of the American Chemical Society. 124:168-168