Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Karine Gombert"'
Autor:
Agnes Cibiel, Nam Nguyen Quang, Karine Gombert, Benoit Thézé, Anikitos Garofalakis, Frédéric Ducongé
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87002 (2014)
BACKGROUND: Cell-SELEX is now widely used for the selection of aptamers against cell surface biomarkers. However, despite negative selection steps using mock cells, this method sometimes results in aptamers against undesirable targets that are expres
Externí odkaz:
https://doaj.org/article/3fd8d52c483644d08bd1ae8b0b388def
Autor:
Laura Cerchia, Frédéric Ducongé, Carine Pestourie, Jocelyne Boulay, Youssef Aissouni, Karine Gombert, Bertrand Tavitian, Vittorio de Franciscis, Domenico Libri
Publikováno v:
PLoS Biology, Vol 3, Iss 4, p e123 (2005)
Targeting large transmembrane molecules, including receptor tyrosine kinases, is a major pharmacological challenge. Specific oligonucleotide ligands (aptamers) can be generated for a variety of targets through the iterative evolution of a random pool
Externí odkaz:
https://doaj.org/article/ead8e11ade264496bfc22f633e942105
Autor:
Frédéric Ducongé, Benoit Thézé, Karine Gombert, Ioanna Theodorou, Edmond Gravel, Parambath Anilkumar, Eric Doris
Publikováno v:
Advanced Functional Materials. 24:5246-5252
The development of a photo-responsive micellar system capable of triggering cell death is reported. Precursors of the micelles are synthesized by connecting a lipophilic chain to a hydrophilic polyethylene glycol via a photo-labile nitrobenzyl group.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e28e638cc918c0de4543e3bd64eff417
https://doi.org/10.1002/adfm.201400840
https://doi.org/10.1002/adfm.201400840
Autor:
Ioanna Theodorou, Nam Nguyen Quang, Benoît Lelandais, Karine Gombert, Frédéric Ducongé, Benoit Thézé
Publikováno v:
Methods in Molecular Biology ISBN: 9781493931965
Fluorescence imaging techniques could be used in different ways to study the interaction of aptamers with biological systems from cell culture to animal models. Here, we present the methods developed in our laboratory for fluorescently labeled aptame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3dd531236d92171c6963274d6d55d50
https://doi.org/10.1007/978-1-4939-3197-2_11
https://doi.org/10.1007/978-1-4939-3197-2_11
Autor:
Bertrand Tavitian, Benoit Mahler, Françoise Hinnen, Laurence Herin, Frédéric Ducongé, Bertrand Kuhnast, Benoit Thézé, Carine Pestourie, Frédéric Dollé, Benoit Dubertret, Thomas Pons, Karine Gombert
Publikováno v:
Bioconjugate Chemistry. 19:1921-1926
We have designed new nanoprobes applicable for both positron emission tomography (PET) and optical fluorescence in vivo imaging. Fluorine-18, which is commonly used for clinical imaging, has been coupled to phospholipid quantum dot (QD) micelles. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b649a85413bacd4b440e0c132cd4684
https://doi.org/10.1021/bc800179j
https://doi.org/10.1021/bc800179j
Autor:
Nam Nguyen Quang, Agnès Cibiel, Anikitos Garofalakis, Frédéric Ducongé, Benoit Thézé, Karine Gombert
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87002 (2014)
PLoS ONE
PLoS ONE
Background Cell-SELEX is now widely used for the selection of aptamers against cell surface biomarkers. However, despite negative selection steps using mock cells, this method sometimes results in aptamers against undesirable targets that are express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afbfff97cfd7d851a3f7fdba61549ec0
http://europepmc.org/articles/PMC3906106?pdf=render
http://europepmc.org/articles/PMC3906106?pdf=render
Autor:
Stéphanie Ricaud, Vincent Chabottaux, Carine Pestourie, Françoise Bruyère, Daniel Lewandowsky, Karine Gombert, Alexandra Paye, Laurent Host, Agnès Noël, Bertrand Tavitian, Frédéric Ducongé, Marc Thiry, Anikitos Garofalakis, Silvia Blacher, Jean-Michel Foidart
Publikováno v:
Journal of Cellular and Molecular Medicine
Journal of Cellular and Molecular Medicine; Vol 13
Journal of Cellular and Molecular Medicine; Vol 13
The present study aims at investigating the mechanism by which membrane-type 4 matrix metalloproteinase (MT4-MMP), a membrane-anchored MMP expressed by human breast tumour cells promotes the metastatic dissemination into lung. We applied experimental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36bea17de88f9f2131565835be91d3ea
https://pubmed.ncbi.nlm.nih.gov/19426156
https://pubmed.ncbi.nlm.nih.gov/19426156
Autor:
Carine Pestourie, Bertrand Kuhnast, Stéphane Le Helleix, Karine Gombert, Frédéric Dollé, Bertrand Tavitian, Frédéric Ducongé, Benoit Thézé
Publikováno v:
European journal of nuclear medicine and molecular imaging. 37(1)
6-[(18)F]Fluoro-3,4-dihydroxy-L-phenylalanine (6-[(18)F]F-L-DOPA) is increasingly used for PET imaging of neuroendocrine tumours. In this study, we investigated the use of 6-[(18)F]F-L-DOPA to detect and to monitor the progression of medullary thyroi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d087e88000f81e5133e4494fec1319
https://pubmed.ncbi.nlm.nih.gov/19690853
https://pubmed.ncbi.nlm.nih.gov/19690853
Autor:
Laura Cerchia, Jocelyne Boulay, Domenico Libri, Karine Gombert, Vittorio de Franciscis, Bertrand Tavitian, Carine Pestourie, Frédéric Ducongé, Youssef Aissouni
Publikováno v:
PLOS Biology. 13:e1002215
The authors and editors retract this publication following an investigation into concerns around the data presented in Figures 3 and 4 that were brought to the editors’ attention. The text below has been agreed to by the editors and authors. Some o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3946e320e7ba2f27f6ac146fa0de03f
https://doi.org/10.1371/journal.pbio.1002215
https://doi.org/10.1371/journal.pbio.1002215
Autor:
Frédéric Ducongé, Domenico Libri, Bertrand Tavitian, Laura Cerchia, Vittorio de Franciscis, Carine Pestourie, Youssef Aissouni, Jocelyne Boulay, Karine Gombert
Publikováno v:
Oligonucleotides
Oligonucleotides, Mary Ann Liebert, 2006, 16 (4), pp.323-35. ⟨10.1089/oli.2006.16.323⟩
Oligonucleotides, 2006, 16 (4), pp.323-35. ⟨10.1089/oli.2006.16.323⟩
Oligonucleotides, Mary Ann Liebert, 2006, 16 (4), pp.323-35. ⟨10.1089/oli.2006.16.323⟩
Oligonucleotides, 2006, 16 (4), pp.323-35. ⟨10.1089/oli.2006.16.323⟩
Binding of aptamers is dependent on their target conformation, which in turn is conditioned by the target's environment. Therefore, selection of aptamers against the active forms of membrane proteins could require their correct membrane insertion in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7b7824b19e8b026c84a1596a0196012
https://hal.archives-ouvertes.fr/hal-00168038
https://hal.archives-ouvertes.fr/hal-00168038