Short-Term Sustained Hypoxia Elevates Basal and Hypoxia-Induced Ventilation but Not the Carotid Body Chemoreceptor Activity in Rats

Autor: Karine C. Flor, Elaine F. Silva, Miguel F. Menezes, Gustavo R. Pedrino, Eduardo Colombari, Daniel B. Zoccal

Publikováno v: Frontiers in Physiology, Vol 9 (2018)

Exposure to chronic sustained hypoxia (SH), as experienced in high altitudes, elicits an increase in ventilation, named ventilatory acclimatization to hypoxia (VAH). We previously showed that rats exposed to short-term (24 h) SH exhibit enhanced abdo

Externí odkaz: https://doaj.org/article/def07d2ff8fa4c52abc3185a78b20813

Centrally acting adrenomedullin in the long‐term potentiation of sympathetic vasoconstrictor activity induced by intermittent hypoxia in rats

Autor: Daniel B. Zoccal, Melina P. da Silva, Davi J. A. Moraes, Karine C. Flor, David Murphy, Debora S. A. Colombari, Eduardo Colombari, Julian F. R. Paton, Benedito H. Machado, João Henrique Costa-Silva

Publikováno v: Zoccal, D B, Colombari, D S A, Colombari, E, Flor, K C, da Silva, M P, Costa-Silva, J H, Machado, B H, Moraes, D J A, Murphy, D & Paton, J F R 2019, ' Centrally acting adrenomedullin in the long-term potentiation of sympathetic vasoconstrictor activity induced by intermittent hypoxia in rats ', Experimental Physiology, vol. 104, no. 9, pp. 1371-1383 . https://doi.org/10.1113/EP087613
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

NEW FINDINGS What is the central question of this study? Adrenomedullin in the rostral ventrolateral medulla (RVLM) increases sympathetic activity; given that adrenomedullin is released during hypoxia, what are the effects of its agonism and antagoni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5899f5c9118c3023b68708670b05ecf6
https://doi.org/10.1113/ep087613

Inhibitory control of active expiration by the Bötzinger complex in rats

Autor: William H. Barnett, Karine C. Flor, Yaroslav I. Molkov, Daniel B. Zoccal, Marlusa Karlen-Amarante

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2020-12-12T02:16:18Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01 Key points: Contraction of abdominal muscles at the end of expiration during metabolic challenges (such as hypercapnia and hypoxia) improves

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb40def9c8a70f12f722de205bb0bf5
https://doi.org/10.1101/2019.12.19.883199