Zobrazeno 1 - 6
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pro vyhledávání: '"Karine Aupeix"'
Autor:
Karine Aupeix, Jean-Jacques Toulmé
Publikováno v:
Scopus-Elsevier
We monitored the binding of triplex-forming oligopyrimidines to the double-stranded stem of the RNA hairpin responsible for the gag-pol frameshift in HIV-1. Whereas the substitution of 5, propynyl-C for C had a limited effect, the use of a Peptide Nu
Publikováno v:
Scopus-Elsevier
Benzo[g]quinazoline-2,4-(1H,3H)-dione (BgQ), a fluorescent thymine analog, was incorporated into an oligopyrimidine (III) able to give rise to a triple-stranded structure by clamping a purine 11-mer (I). The formation of the I-III complex resulted in
Autor:
Karine Aupeix, Jean-Marie Freyssinet, Marielle Christ, D. Weltin, José E. Mejía, Jean Marchal, Pierre Bischoff
Publikováno v:
Immunobiology. 194:415-428
Oxysterols constitute a large family of natural compounds, endowed with various biological activities including cholesterol regulation, immunosuppression and antitumoral potency. In the present study, we examine and compare the cytotoxic effects of t
Publikováno v:
The Biochemical journal. 314
Oxidized cholesterol compounds or oxysterols are thought to be potent membrane-destabilizing agents. Anionic phospholipids, chiefly phosphatidylserine, have a procoagulant potential due to their ability to favour the membrane assembly of the characte
Publikováno v:
FEBS Letters. (2-3):169-174
The 12 bp stem of the RNA hairpin responsible for the gag-pol frameshifting of the ribosomes during translation of the polycistronic HIV-1 mRNA has a pyrimidine-rich 5′ strand and, consequently, a purine-rich 3′ strand. Electrophoretic mobility s
Autor:
Laure Bidou, Sandrine Chabas, Jean-Jacques Toulmé, Marc Leng, Karine Aupeix-Scheidler, Jean-Pierre Rousset
Publikováno v:
Scopus-Elsevier
A 2'-O-methylribooligonucleotide containing a G1.U.G3 triad modified by trans-diamminedichloro-platinum(II) was targeted to the RNA region responsible for the gag-pol frameshifting during translation of the HIV-1 mRNA. The binding of the platinated o
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