An exome-wide study of renal operational tolerance

Autor: Annick Massart, Richard Danger, Catharina Olsen, Mary J. Emond, Ondrej Viklicky, Valérie Jacquemin, Julie Soblet, Sarah Duerinckx, Didier Croes, Camille Perazzolo, Petra Hruba, Dorien Daneels, Ben Caljon, Mehmet Sukru Sever, Julio Pascual, Marius Miglinas, the Renal Tolerance Investigators, Isabelle Pirson, Lidia Ghisdal, Guillaume Smits, Magali Giral, Daniel Abramowicz, Marc Abramowicz, Sophie Brouard, Maria Aguilar Rodríguez, Friederike Bachmann, Rajendra Bahadur Shahi, Frederike Bemelman, Luboslav Bena, Luigi Biancone, Laura Braun, Klemens Budde, Alejandro Camargo-Salamanca, Katia Clemente, Hulya Colak, Adrian Covic, Jacques Degreve, Philippe Gatault, François Glowacki, Karine Hadaya, Marc Hazzan, Bénédicte Janbon, Christophe Legendre, Umberto Maggiore, Anja Mühlfeld, Maarten Naesens, Christian Noël, Rainer Oberbauer, Evangeline Pillebout, Gian Benedetto Piredda, Francesco Pisani, Ana Ramírez Puga, Tomas Reischig, Francisco González-Roncero, Søren Schwartz Sørensen, Daniel Seron Micas, Nurhan Seyahi, Dimitrie Siriopol, Goce Spasovski, Jean-François Subra, Erik Teugels, Serhan Tuǧlular, Sonia Van Dooren, Catheline Vilain, Florence Villemain, Xavier Warling, Bruno Watschinger, Laurent Weekers

Publikováno v: Frontiers in Medicine, Vol 9 (2023)

BackgroundRenal operational tolerance is a rare and beneficial state of prolonged renal allograft function in the absence of immunosuppression. The underlying mechanisms are unknown. We hypothesized that tolerance might be driven by inherited protein

Externí odkaz: https://doaj.org/article/728d19d9593f48acbfe88073eed48e31

Donation type and the effect of pre-transplant donor specific antibodies – Data from the Swiss Transplant Cohort Study

Autor: Olivier de Rougemont, Yun Deng, Lukas Frischknecht, Caroline Wehmeier, Jean Villard, Sylvie Ferrari-Lacraz, Déla Golshayan, Monique Gannagé, Isabelle Binet, Urs Wirthmueller, Daniel Sidler, Thomas Schachtner, Stefan Schaub, Jakob Nilsson, the Swiss Transplant Cohort Study, Patrizia Amico, Andres Axel, John David Aubert, Vanessa Banz, Beckmann Sonja, Guido Beldi, Christoph Berger, Ekaterine Berishvili, Pierre-Yves Bochud, Sanda Branca, Heiner Bucher, Thierry Carrel, Emmanuelle Catana, Yves Chalandon, Sabina De Geest, Olivier De Rougemont, Michael Dickenmann, Joëlle Lynn Dreifuss, Michel Duchosal, Thomas Fehr, Nicola Franscini, Christian Garzoni, Paola Gasche Soccal, Christophe Gaudet, Nicolas Goossens, Karine Hadaya, Jörg Halter, Dominik Heim, Christoph Hess, Sven Hillinger, Hans Hirsch, Patricia Hirt, Günther Hofbauer, Uyen Huynh-Do, Franz Immer, Michael Koller, Mirjam Laager, Bettina Laesser, Roger Lehmann, Alexander Leichtle, Christian Lovis, Oriol Manuel, Hans-Peter Marti, Pierre Yves Martin, Michele Martinelli, Valérie McLin, Katell Mellac, Aurelia Mercay, Karin Mettler, Nicolas Mueller, Antonia Müller, Thomas Müller, Ulrike Müller-Arndt, Beat Müllhaupt, Mirjam Nägeli, Graziano Oldani, Manuel Pascual, Klara Posfay-Barbe, Juliane Rick, Anne Rosselet, Simona Rossi, Silvia Rothlin, Frank Ruschitzka, Urs Schanz, Aurelia Schnyder, Macé Schuurmans, Thierry Sengstag, Federico Simonetta, Katharina Staufer, Susanne Stampf, Jürg Steiger, Guido Stirniman, Ueli Stürzinger, Christian Van Delden, Jean-Pierre Venetz, Julien Vionnet, Madeleine Wick, Markus Wilhlem, Patrick Yerly

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

IntroductionThe type of donation may affect how susceptible a donor kidney is to injury from pre-existing alloimmunity. Many centers are, therefore, reluctant to perform donor specific antibody (DSA) positive transplantations in the setting of donati

Externí odkaz: https://doaj.org/article/4477ab4529c049ca9d56bbf4349cc853

Demographic, psychosocial and health disparities between living and deceased renal allograft recipients in Switzerland

Autor: Rita Achermann, Michael Koller, Sabina De Geest, Karine Hadaya, Thomas F. Müller, Uyen Huynh-Do, Manuel Pascual, Jürg Steiger, Alexander Kiss, Isabelle Binet

Publikováno v: Swiss Medical Weekly, Vol 151, Iss 3132 (2021)

BACKGROUND Living donor renal transplantation is widely performed in Switzerland with a superior long-term outcome and lower waiting time compared with deceased renal transplantation. However the chances of receiving a living donor kidney transplant

Externí odkaz: https://doaj.org/article/accd59aa146b402694fbf67b31ac83da

Immunosuppression management in renal transplant recipients with normal-immunological risk: 10-year results from the Swiss Transplant Cohort Study

Autor: Andreas Krisl, Susanne Stampf, Dimitri Hauri, Isabelle Binet, Thomas Mueller, Daniel Sidler, Karine Hadaya, Déla Golshayan, Manuel Pascual, Michael Koller, Michael Dickenmann, the Swiss Transplant Cohort Study (STCS)

Publikováno v: Swiss Medical Weekly, Vol 150, Iss 4950 (2020)

AIMS OF THE STUDY Primary maintenance immunosuppressive therapies for renal transplant recipients underwent significant changes in recent years. We aimed to assess time trends and the impact of immunosuppressive regimens in first renal transplant re

Externí odkaz: https://doaj.org/article/df022b1e9a8546cea82a492b3953a241

Preservation of kidney function in kidney transplant recipients by alkali therapy (Preserve-Transplant Study): rationale and study protocol

Autor: Anna Wiegand, Alexander Ritter, Nicole Graf, Spyridon Arampatzis, Daniel Sidler, Karine Hadaya, Thomas F. Müller, Carsten A. Wagner, Rudolf P. Wüthrich, Nilufar Mohebbi

Publikováno v: BMC Nephrology, Vol 19, Iss 1, Pp 1-7 (2018)

Abstract Background Graft survival after kidney transplantation has significantly improved within the last decades but there is a substantial number of patients with declining transplant function and graft loss. Over the past years several studies ha

Externí odkaz: https://doaj.org/article/1aaa4e6ad34a440c9d408bd09d2d19bd