Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Karina eClaassen"'
Publikováno v:
Frontiers in Physiology, Vol 4 (2013)
The renin-angiotensin-aldosterone system (RAAS) plays a key role in the pathogenesis of cardiovascular disorders including hypertension and is one of the most important targets for drugs. A whole body physiologically-based pharmacokinetic (wb PBPK) m
Externí odkaz:
https://doaj.org/article/ef0c720d57a64fd3a9a13d1240f59ebd
Autor:
Christoph eNiederalt, Thomas eWendl, Lars eKuepfer, Karina eClaaßen, Roland eLoosen, Stefan eWillmann, Jörg eLippert, Marcus eSchultze-Mosgau, Julia eWinkler, Rolf eBurghaus, Matthias eBräutigam, Hubertus ePietsch, Philipp eLengsfeld
Publikováno v:
Frontiers in Physiology, Vol 3 (2013)
A physiologically-based kidney model was developed to analyze the renal excretion and kidney exposure of hydrophilic agents, in particular contrast media, in rats. In order to study the influence of osmolality and viscosity changes, the model mechani
Externí odkaz:
https://doaj.org/article/5397972ac26b47c5bee4111be6a6fc6b