Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Karina Wright"'
Autor:
Raneem Kalsoum, Catherine J. Minns Lowe, Sophie Gilbert, Andrew W. McCaskie, Martyn Snow, Karina Wright, Geoff Bruce, Deborah J. Mason, Fiona E. Watt
Publikováno v:
Bone & Joint Research, Vol 13, Iss 9, Pp 513-524 (2024)
Aims: To explore key stakeholder views around feasibility and acceptability of trials seeking to prevent post-traumatic osteoarthritis (PTOA) following knee injury, and provide guidance for next steps in PTOA trial design. Methods: Healthcare profess
Externí odkaz:
https://doaj.org/article/a7fb3a391e62420ea564514ad9baa7fd
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Stimulating meniscus regeneration using meniscal progenitor cells has been suggested as a promising new strategy. However, there is a lack of studies which decisively identify and characterize progenitor cell populations in human meniscus tissues. In
Externí odkaz:
https://doaj.org/article/9e9b9385f71e4bc797dbd8f82949a5f6
Autor:
Jingsong Wang, Sally Roberts, Jan Herman Kuiper, Weiguo Zhang, John Garcia, Zhanfeng Cui, Karina Wright
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Meniscus degeneration is closely related to the progression of knee osteoarthritis (OA). However, there is currently a lack of quantitative and objective metrics to assess OA meniscal cell phenotypes. In this study we investigated the phenot
Externí odkaz:
https://doaj.org/article/4b449fd555fd4488a242218d7f8e8683
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-15 (2019)
Abstract Background The manufacture of mesenchymal stem/stromal cells (MSCs) for clinical use needs to be cost effective, safe and scaled up. Current methods of expansion on tissue culture plastic are labour-intensive and involve several ‘open’ p
Externí odkaz:
https://doaj.org/article/2a22d0a0c9fa486881dfd6f3abc6ce1f
Autor:
John Garcia, Charlotte Hulme, Claire Mennan, Sally Roberts, Yvonne M. Bastiaansen-Jenniskens, Gerjo J.V.M. van Osch, Bernhard Tins, Peter Gallacher, Karina Wright
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 2, Iss 2, Pp 100039- (2020)
Objective: The synovial fluid (SF) of patients with focal cartilage defects contains a population of poorly characterised cells that could have pathophysiological implications in early osteoarthritis and joint tissue repair. We have examined the cell
Externí odkaz:
https://doaj.org/article/95b9ac70b09d44f597e1f4e38f418ebf
Autor:
Jade Perry, Anke J. Roelofs, Claire Mennan, Helen S. McCarthy, Alison Richmond, Susan M. Clark, Anna H. K. Riemen, Karina Wright, Cosimo De Bari, Sally Roberts
Publikováno v:
Cells, Vol 10, Iss 8, p 1999 (2021)
Human umbilical cord (hUC)- or bone marrow (hBM)-derived mesenchymal stromal cells (MSCs) were evaluated as an allogeneic source of cells for cartilage repair. We aimed to determine if they could enhance healing of chondral defects with or without th
Externí odkaz:
https://doaj.org/article/7728aff2422f4e3e9ad93776dd2b2f42
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e2934 (2008)
Mesenchymal stem cells (MSCs) are non-haematopoeitic, stromal cells that are capable of differentiating into mesenchymal tissues such as bone and cartilage. They are rare in bone marrow, but have the ability to expand many-fold in culture, and retain
Externí odkaz:
https://doaj.org/article/8a5e38c450954208ad2cbde0d7045a16
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9242
The immunomodulatory properties of MSCs can be recreated using their extracellular vesicles (EVs). Yet, the true capabilities of the MSC EVs cannot be distinguished from contaminating bovine EVs and protein derived from supplemental foetal bovine ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e69a65a8bd3c0a90888b377fe74f4db
Publikováno v:
Cureus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::094704e46e0ea816ec70f262c69f0594
https://doi.org/10.7759/cureus.38788
https://doi.org/10.7759/cureus.38788
Autor:
Charlotte H. Hulme, Claire Mennan, Helen S. McCarthy, Rebecca Davies, Tian Lan, Larissa Rix, Jade Perry, Karina Wright
Publikováno v:
Cytotherapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5498b8f41e7d8de732ff6bfc1486d9ad
https://doi.org/10.1016/j.jcyt.2023.04.004
https://doi.org/10.1016/j.jcyt.2023.04.004