Time-restricted feeding improves adaptation to chronically alternating light-dark cycles

Autor: Rosa van den Berg, Conny T. M. van Oostrom, Martijn E.T. Dollé, Till Roenneberg, Tom Deboer, Linda W. M. van Kerkhof, Lauren L. Tambyrajah, Gerben Hulsegge, Maaike Schilperoort, Nienke R. Biermasz, Karin I. Proper, Karina Wagner, Harry van Steeg, Sander Kooijman, Paul F.K. Wackers, Patrick C.N. Rensen

Publikováno v: Scientific Reports
Scientific Reports, 9(1):7874. Nature Publishing Group
Scientific Reports, 9
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)

Disturbance of the circadian clock has been associated with increased risk of cardio-metabolic disorders. Previous studies showed that optimal timing of food intake can improve metabolic health. We hypothesized that time-restricted feeding could be a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65887ef9e66de5c7177bf4caf39ab474
http://europepmc.org/articles/PMC6536683

Stepwise Assembly of Dimeric F1Fo-ATP Synthase in Mitochondria Involves the Small Fo-Subunits k and i

Autor: Christiane D. Fichter, Martin van der Laan, Inge Perschil, Karina Wagner

Publikováno v: Molecular Biology of the Cell

Oligomerization of F1Fo-ATP synthase in the inner mitochondrial membrane governs the formation of cristae membrane domains. We show that the F1Fo-subunits Su i and Su k are crucial for the formation and maturation of ATP synthase dimers and oligomers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896d786d30e168f1f4fde1275cb3e7a6
https://doi.org/10.1091/mbc.e09-12-1023

The Assembly Pathway of the Mitochondrial Carrier Translocase Involves Four Preprotein Translocases

Autor: Katrin Brandner, Peter Rehling, Nils Wiedemann, Bernard Guiard, Nikolaus Pfanner, Karina Wagner, Natalia Gebert, Kaye N. Truscott

Publikováno v: Molecular and Cellular Biology. 28:4251-4260

The mitochondrial inner membrane contains preprotein translocases that mediate insertion of hydrophobic proteins. Little is known about how the individual components of these inner membrane preprotein translocases combine to form multisubunit complex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efcca6b5f1a75f40fbc7e720e0b49d33
https://doi.org/10.1128/mcb.02216-07

Shy1 couples Cox1 translational regulation to cytochrome c oxidase assembly

Autor: Inge Perschil, Martin van der Laan, Bettina Warscheid, Karina Wagner, David U. Mick, Ann E. Frazier, Magdalena Pawlas, Peter Rehling, Helmut E. Meyer

Publikováno v: The EMBO Journal. 26:4347-4358

Cytochrome c oxidase (complex IV) of the respiratory chain is assembled from nuclear and mitochondrially-encoded subunits. Defects in the assembly process lead to severe human disorders such as Leigh syndrome. Shy1 is an assembly factor for complex I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e12e1f7e18bf48a0a90faa494c469cec
https://doi.org/10.1038/sj.emboj.7601862

Mitochondrial F1Fo-ATP synthase: the small subunits e and g associate with monomeric complexes to trigger dimerization

Autor: Rebecca D. Taylor, Martin van der Laan, Peter Rehling, Karina Wagner, Nikolaus Pfanner, Luiza K. Sanjuán Szklarz

Publikováno v: Journal of molecular biology. 392(4)

Mitochondrial F 1 F o -ATP synthase catalyzes the formation of ATP from ADP and inorganic phosphate. The enzyme is found in monomeric, dimeric and higher oligomeric forms in the inner mitochondrial membrane. Dimerization of ATP synthase complexes is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f311606efad6ed24690bd17741a64968
https://pubmed.ncbi.nlm.nih.gov/19635484