Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Karina Thieme"'
Autor:
Guilherme Lopes-Gonçalves, Juliana Martins Costa-Pessoa, Ruan Pimenta, Ana Flavia Tostes, Eloisa Martins da Silva, Felipe Lourenço Ledesma, Denise Maria Avancini Costa Malheiros, Roberto Zatz, Karina Thieme, Niels Olsen Saraiva Câmara, Maria Oliveira-Souza
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Focal segmental glomerulosclerosis (FSGS) is the leading cause of nephrotic syndrome, which is characterized by podocyte injury. Given that the pathophysiology of nondiabetic glomerulosclerosis is poorly understood and targeted therapies to
Externí odkaz:
https://doaj.org/article/7c2b6a9725664b6681f6b38bddc8992b
Autor:
Beatriz Maria Veloso Pereira, Mariana Charleaux de Ponte, Ana Paula Malavolta Luz, Karina Thieme
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Diabetic kidney disease (DKD) is the leading cause of the end-stage renal disease. Recent studies have shown that epigenetic modifications contribute to alterations in gene expression and the development of DKD. This study aimed to show an expression
Externí odkaz:
https://doaj.org/article/a82e5ba8773145e7a7e390818d7b483a
Autor:
Guiomar Nascimento Gomes, Karina Thieme, Syamantak Majumder, Mychel Raony Paiva Teixeira Morais
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/9ac6ca2bd4ed4d88b8aa7a7eb3284969
Autor:
Niyati Pandya Thakkar, Beatriz Maria Veloso Pereira, Yash T. Katakia, Shyam Kumar Ramakrishnan, Sumukh Thakar, Ashima Sakhuja, Gayathry Rajeev, S. Soorya, Karina Thieme, Syamantak Majumder
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Endothelial-to-mesenchymal transition (EndMT) is a hallmark of diabetes-associated vascular complications. Epigenetic mechanisms emerged as one of the key pathways to regulate diabetes-associated complications. In the current study, we aimed to deter
Externí odkaz:
https://doaj.org/article/623d8cb70f3d4f6698c765c80d8b86b5
Autor:
Guiomar Nascimento Gomes, Minolfa C. Prieto, Karina Thieme, Heloisa Della Coletta Francescato
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/53ad424974f344eda4d1dc33ea8e7216
Autor:
Rogério Argeri, Fernanda Thomazini, Débora Conte Kimura Lichtenecker, Karina Thieme, Maria do Carmo Franco, Guiomar Nascimento Gomes
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The Barker hypothesis strongly supported the influence of fetal environment on the development of chronic diseases in later life. Multiple experimental and human studies have identified that the deleterious effect of fetal programming commonly leads
Externí odkaz:
https://doaj.org/article/12faf185a5794f07866134a06ac9b2ea
Autor:
Maria Beatriz Monteiro, Tatiana S. Pelaes, Daniele P. Santos-Bezerra, Karina Thieme, Antonio M. Lerario, Sueli M. Oba-Shinjo, Ubiratan F. Machado, Marisa Passarelli, Suely K. N. Marie, Maria Lúcia Corrêa-Giannella
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Introduction: Using a discovery/validation approach we investigated associations between a panel of genes selected from a transcriptomic study and the estimated glomerular filtration rate (eGFR) decline across time in a cohort of type 1 diabetes (T1D
Externí odkaz:
https://doaj.org/article/5a4e3390fcd54a8196ea42af99e1dff6
Autor:
Vanessa Gerolde Cardoso, Guilherme Lopes Gonçalves, Juliana Martins Costa-Pessoa, Karina Thieme, Bruna Bezerra Lins, Fernando Augusto Malavazzi Casare, Mariana Charleaux de Ponte, Niels Olsen Saraiva Camara, Maria Oliveira-Souza
Publikováno v:
BMC Nephrology, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background Angiotensin II (Ang II) contributes to the progression of renal diseases associated with proteinuria and glomerulosclerosis mainly by inducing podocyte apoptosis. In the present study, we investigated whether the chronic effects o
Externí odkaz:
https://doaj.org/article/e9b4fd1bd60f4caa81f7d5450e467fb8
Autor:
Mariana Charleaux de Ponte, Fernando Augusto Malavazzi Casare, Juliana Martins Costa-Pessoa, Vanessa Gerolde Cardoso, Gerhard Malnic, Margarida Mello-Aires, Rildo Aparecido Volpini, Karina Thieme, Maria Oliveira-Souza
Publikováno v:
Kidney & Blood Pressure Research, Vol 42, Iss 6, Pp 1277-1289 (2017)
Background/Aims: To assess the possible contribution of the β-adrenergic overstimulation in early stages of renal injury, the present study evaluated, in rats, the effects of the β-adrenoceptor agonist isoproterenol (ISO) on renal function and morp
Externí odkaz:
https://doaj.org/article/c82e859372ba46f39dce0474bcc93383
Autor:
Karina Thieme, Syamantak Majumder, Angela S. Brijmohan, Sri N. Batchu, Bridgit B. Bowskill, Tamadher A. Alghamdi, Suzanne L. Advani, M. Golam Kabir, Youan Liu, Andrew Advani
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The therapeutic targeting of prostanoid subtype receptors may slow the development of chronic kidney disease (CKD) through mechanisms that are distinct from those of upstream COX inhibition. Here, employing multiple experimental models of CK
Externí odkaz:
https://doaj.org/article/3c7f7c6c5c3f478c808baefc6898c731