Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Karina Ramalho Bortoluci"'
Autor:
Marcelo Pires Amaral, Felipe Daniel Cardoso, Ingrid Sancho de Farias, Rafael Queiroz de Souza, Kely Catarine Matteucci, Ana Claudia Torrecilhas, Karina Ramalho Bortoluci
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Inflammasomes are large protein complexes that, once activated, initiate inflammatory responses by activating the caspase-1 protease. They play pivotal roles in host defense against pathogens. The well-established role of NAIP/NLRC4 inflammasome in b
Externí odkaz:
https://doaj.org/article/2317948a518d4126a63e6ffdc884b5f0
Autor:
Laura Migliari Branco, Marcelo Pires Amaral, Henning Boekhoff, Ana Beatriz Figueiredo de Lima, Ingrid Sancho Farias, Silvia Lucena Lage, Gustavo José Silva Pereira, Bernardo Simões Franklin, Karina Ramalho Bortoluci
Publikováno v:
Cell Death and Disease, Vol 13, Iss 12, Pp 1-10 (2022)
Abstract The NAIP/NLRC4 inflammasome is classically associated with the detection of bacterial invasion to the cytosol. However, recent studies have demonstrated that NAIP/NLRC4 is also activated in non-bacterial infections, and in sterile inflammati
Externí odkaz:
https://doaj.org/article/0d5a4821332f4b70a59baaf70c4b95da
Autor:
Mariana Teixeira Rodrigues, Ana Paula Picaro Michelli, Gustavo Felisola Caso, Paloma Ramos de Oliveira, Dorival Mendes Rodrigues-Junior, Mirian Galliote Morale, Joel Machado Júnior, Karina Ramalho Bortoluci, Rodrigo Esaki Tamura, Tamiris Reissa Cipriano da Silva, Cristiano Raminelli, Eric Chau, Biana Godin, Jamile Calil-Silveira, Ileana G. Sanchez Rubio
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1687 (2023)
Anaplastic thyroid cancer (ATC) is an aggressive form of thyroid cancer (TC), accounting for 50% of total TC-related deaths. Although therapeutic approaches against TC have improved in recent years, the survival rate remains low, and severe adverse e
Externí odkaz:
https://doaj.org/article/a71652dc442f4d3a9f88edb218ec1cd7
Autor:
Luiza Zainotti Miguel Fahur Bottino, Dorival Mendes Rodrigues-Junior, Ingrid Sancho de Farias, Laura Migliari Branco, N. Gopalakrishna Iyer, Gabriela Estrela de Albuquerque, André Luiz Vettore, Karina Ramalho Bortoluci
Publikováno v:
Current Research in Immunology, Vol 2, Iss , Pp 175-183 (2021)
The content of tumor-derived extracellular vesicles (EVs) can regulate the tumor microenvironment and functionally acts in favor of cancer aggressiveness. To better elucidate the role of EVs in the interplay between immune system and tumor microenvir
Externí odkaz:
https://doaj.org/article/1b730a4945f9407f8a40a7d852131a62
Autor:
Camila Pontes Ferreira, Leonardo Moro Cariste, Isaú Henrique Noronha, Danielle Fernandes Durso, Joseli Lannes-Vieira, Karina Ramalho Bortoluci, Daniel Araki Ribeiro, Douglas Golenbock, Ricardo Tostes Gazzinelli, José Ronnie Carvalho de Vasconcelos
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 4, p e0009326 (2021)
[This corrects the article DOI: 10.1371/journal.pntd.0008414.].
Externí odkaz:
https://doaj.org/article/f8c003fb869b46bb85dbd363e5d5e3a5
Autor:
Camila Pontes Ferreira, Leonardo Moro Cariste, Isaú Henrique Noronha, Danielle Fernandes Durso, Joseli Lannes-Vieira, Karina Ramalho Bortoluci, Daniel Araki Ribeiro, Douglas Golenbock, Ricardo Tostes Gazzinelli, José Ronnie Carvalho de Vasconcelos
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 6, p e0008414 (2020)
Chemokine receptor type 3 (CXCR3) plays an important role in CD8+ T cells migration during intracellular infections, such as Trypanosoma cruzi. In addition to chemotaxis, CXCR3 receptor has been described as important to the interaction between antig
Externí odkaz:
https://doaj.org/article/23e3419d6736425f9d89132b616384fb
Autor:
José Marcos Sanches, Laura Migliari Branco, Gustavo Henrique Bueno Duarte, Sonia Maria Oliani, Karina Ramalho Bortoluci, Vanessa Moreira, Cristiane Damas Gil
Publikováno v:
Cells, Vol 9, Iss 4, p 926 (2020)
Annexin A1 (AnxA1) is a potent anti-inflammatory protein that downregulates proinflammatory cytokine release. This study evaluated the role of AnxA1 in the regulation of NLRP3 inflammasome activation and lipid release by starch-elicited murine perito
Externí odkaz:
https://doaj.org/article/e70cd48e82ee4c4894bf23017f51321c
Autor:
Jonatan Ersching, Alexandre Salgado Basso, Vera Lúcia Garcia Calich, Karina Ramalho Bortoluci, Maurício M Rodrigues
Publikováno v:
PLoS Pathogens, Vol 12, Iss 7, p e1005771 (2016)
[This corrects the article DOI: 10.1371/journal.ppat.1005698.].
Externí odkaz:
https://doaj.org/article/daa8f32b100c47bc97ef7b9f3137e768
Autor:
Jonatan Ersching, Alexandre Salgado Basso, Vera Lucia Garcia Kalich, Karina Ramalho Bortoluci, Maurício M Rodrigues
Publikováno v:
PLoS Pathogens, Vol 12, Iss 6, p e1005698 (2016)
Although CD4+ Foxp3+ T cells are largely described in the regulation of CD4+ T cell responses, their role in the suppression of CD8+ T cell priming is much less clear. Because the induction of CD8+ T cells during experimental infection with Trypanoso
Externí odkaz:
https://doaj.org/article/bf23b7099f3d425da6796448541b8875
Publikováno v:
Frontiers in Immunology, Vol 6 (2015)
Tissue macrophages play a crucial role in the maintenance of tissue homeostasis and also contribute to inflammatory and reparatory responses during pathogenic infection and tissue injury. The high heterogeneity of these macrophages is consistent with
Externí odkaz:
https://doaj.org/article/0c27dac0d36145148070ae14c6a0c8af