Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Karina Pombo-García"'
Biomolecular condensates enable cell compartmentalization by acting as membrane-less organelles1. How cells control the interactions of condensates with other cellular structures such as membranes to drive morphological transitions remains poorly und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0494c6495e44325df36048057fdcbad8
https://doi.org/10.1101/2022.12.16.520750
https://doi.org/10.1101/2022.12.16.520750
Autor:
Shaon Basu, Paula Martínez-Cristóbal, Mireia Pesarrodona, Marta Frigolé-Vivas, Michael Lewis, Elzbieta Szulc, C. Adriana Bañuelos, Carolina Sánchez-Zarzalejo, Stasė Bielskutė, Jiaqi Zhu, Karina Pombo-García, Carla Garcia-Cabau, Cristina Batlle, Borja Mateos, Mateusz Biesaga, Albert Escobedo, Lídia Bardia, Xavier Verdaguer, Alessandro Ruffoni, Nasrin R. Mawji, Jun Wang, Teresa Tam, Isabelle Brun-Heath, Salvador Ventura, David Meierhofer, Jesús García, Paul Robustelli, Travis H. Stracker, Marianne D. Sadar, Antoni Riera, Denes Hnisz, Xavier Salvatella
SummaryTranscription factors are among the most attractive therapeutic targets but are considered largely undruggable due to the intrinsically disordered nature of their activation domains. Here we show that the aromatic character of the activation d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::647a49166ea017e1660f5ae923fe0668
https://doi.org/10.1101/2022.08.18.504385
https://doi.org/10.1101/2022.08.18.504385
Publikováno v:
Current opinion in cell biology. 77
Epithelial junctions are transmembrane protein complexes that regulate cell adhesion, cell polarity, tissue permeability, and tissue mechanics. Most junctional complexes contain membrane attached cytoplasmic plaques that regulate junction assembly an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3df3355608bc6b34d6bc95402c19079
https://pubmed.ncbi.nlm.nih.gov/35696872
https://pubmed.ncbi.nlm.nih.gov/35696872
Autor:
Leone Spiccia, Peter Comba, Raymond W. Lam, Carmen L. Rühl, José A. Barreto, Tanmaya Joshi, Peter J. Scammells, Karina Pombo-García, Ching-Seng Ang, Bim Graham, Holger Stephan
Publikováno v:
ChemPlusChem. 82:638-646
Polyacrylic-acid-coated ultra-small super-paramagnetic iron oxide nanoparticles were surface-modified with low-molecular-weight sulfobetaines or 3-(diethylamino)propylamine in order to generate nanoparticles with zwitterionic character (ZW-NPs). The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d4a8f9db1f730a48d79904ce0e99fb
https://doi.org/10.1002/cplu.201700052
https://doi.org/10.1002/cplu.201700052
Autor:
Johanna Pufe, Jens Pietzsch, Holger Stephan, Jürgen Seidel, Stephan Weiss, Karina Pombo-García, Kristof Zarschler, Leone Spiccia, Sebastian Meister, Bim Graham, René Hübner, Ching-Seng Ang
Publikováno v:
ChemNanoMat. 2:959-971
We report the synthesis and detailed in vitro evaluation of zwitterionic ultrasmall superparamagnetic iron oxide NPs (USPIONs) comprised of oleic acid/oleyl alcohol-stabilized magnetite particles (5 nm core diameter) coated with an amphiphilic zwitte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f48b60cad8b7eaaab4a8167c38dfedf9
https://doi.org/10.1002/cnma.201600233
https://doi.org/10.1002/cnma.201600233
Autor:
Holger Stephan, Ester Polo, Louise Rocks, Luca Boselli, Nadia Licciardello, Karina Pombo García, Kristof Zarschler, Kenneth A. Dawson, Luisa De Cola
Publikováno v:
Nanomedicine: Nanotechnology, Biology, and Medicine 12(2016)6, 1663-1701
Nanomedicine: Nanotechnology, Biology and Medicine
Nanomedicine: Nanotechnology, Biology and Medicine
Ultrasmall nanoparticulate materials with core sizes in the 1-3 nm range bridge the gap between single molecules and classical, larger-sized nanomaterials, not only in terms of spatial dimension, but also as regards physicochemical and pharmacokineti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d6ce0c1072691b88ed32a446b0f3d8
https://doi.org/10.1016/j.nano.2016.02.019
https://doi.org/10.1016/j.nano.2016.02.019
Autor:
Bim Graham, Katrin Viehweger, Leone Spiccia, Lisa Barbaro, Jörg Steinbach, Holger Stephan, Tanmaya Joshi, Gerhard Geipel, Karina Pombo García
Publikováno v:
Bioconjugate chemistry. 25(5)
A new Boc-protected 1,4,7-triazacyclononane (TACN)-based pro-chelator compound featuring a "clickable" azidomethylpyridine pendant has been developed as a building block for the construction of multimodal imaging agents. Conjugation to a model alkyne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdf94352473862bf1484e1f3583b4a76
https://pubmed.ncbi.nlm.nih.gov/24758412
https://pubmed.ncbi.nlm.nih.gov/24758412
Autor:
Holger Stephan, Karina Pombo García, José A. Barreto, Leone Spiccia, Kristof Zarschler, Lisa Barbaro, William O'Malley, Bim Graham
Publikováno v:
Small 10(2014), 2516-2529
Nanoparticles represent highly promising platforms for the development of imaging and therapeutic agents, including those that can either be detected via more than one imaging technique (multi-modal imaging agents) or used for both diagnosis and ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd583a80bc40b8bd1ad21f1437b7249
https://www.hzdr.de/publications/Publ-20719-1
https://www.hzdr.de/publications/Publ-20719-1
Autor:
Leone Spiccia, William O'Malley, Holger Stephan, Kristof Zarschler, José A. Barreto, Lisa Barbaro, Karina Pombo García, Bim Graham
Publikováno v:
Small. 10:2505-2505
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::144c2578cc73df95794e758a7edad1a9
https://doi.org/10.1002/smll.201470074
https://doi.org/10.1002/smll.201470074
Autor:
Holger Stephan, Bim Graham, Karina Pombo-García, Julia Hesse, Leone Spiccia, Kristof Zarschler, José A. Barreto
Publikováno v:
RSC Advances 3(2013), 22443-22454
The application of ultra-small super-paramagnetic iron oxide nanoparticles (USPIONs) as versatile diagnostic probes for multimodal imaging in biomedicine, including via magnetic resonance imaging (MRI) and positron emission tomography (PET), requires
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fde40f3d785e2336227c921f95c65f0
https://doi.org/10.1039/c3ra43726d
https://doi.org/10.1039/c3ra43726d