VPA/PLGA microfibers produced by coaxial electrospinning for the treatment of central nervous system injury

Autor: Cristian Euzebio Teixeira, Karina Pires Reis, Letícia Scherer Koester, Laura-Elena Sperling, L. Sommer, M. Colombo, Patricia Pranke

Publikováno v: Brazilian Journal of Medical and Biological Research, Volume: 53, Issue: 4, Article number: e8993, Published: 09 APR 2020
Brazilian Journal of Medical and Biological Research, Vol 53, Iss 4 (2020)
Brazilian Journal of Medical and Biological Research v.53 n.4 2020
Brazilian Journal of Medical and Biological Research
Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC

The central nervous system shows limited regenerative capacity after injury. Spinal cord injury (SCI) is a devastating traumatic injury resulting in loss of sensory, motor, and autonomic function distal from the level of injury. An appropriate combin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56fdbe3183a849f656858fb2bde85e07
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2020000400606&lng=en&tlng=en

Galantamine improves functional recovery and reduces lesion size in a rat model of spinal cord injury

Autor: Cristian Euzebio Teixeira, Laura E. Sperling, Marcelo Garrido dos Santos, Carlos Alexandre Netto, Eduardo Luis Konrath, Fabrício do Couto Nicola, Gabriele Gulielmin Didó, Karina Pires Reis, Patricia Pranke

Publikováno v: Brain research. 1724

Spinal cord injury (SCI) is a medical condition that currently lacks effective treatment. Galantamine is a reversible, competitive acetylcholinesterase inhibitor, used to treat patients with Alzheimeŕs disease. It has been demonstrated that galantam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12af58a00c64e8b194cd4b7bdba187e2
https://pubmed.ncbi.nlm.nih.gov/31472112

Repeated three-hour maternal deprivation as a model of early-life stress alters maternal behavior, olfactory learning and neural development

Autor: Débora Czarnabay, Jeferson Dalmago, Arthur Sardi Martins, Karina Pires Reis, Fernando Benetti, Ariley Queiroz, Laura-Elena Sperling, Patricia Pranke

Publikováno v: Neurobiology of learning and memory. 163

Early life stress such as physical abuse, trauma or neglect during a critical period of development can elicit negative long-lasting effects on health. Neonatal maternal deprivation (MD) is a stressful event capable of triggering structural and neuro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82cea0ec95b50e34bbedaec48b4e3f72
https://pubmed.ncbi.nlm.nih.gov/31310813

Effect of co-culture of mesenchymal stem/stromal cells with pancreatic islets on viability and function outcomes: a systematic review and meta-analysis

Autor: Daisy Crispim, Bianca Marmontel de Souza, Patricia Klarmann Ziegelmann, Fernanda dos Santos de Oliveira, Karina Pires Reis, Ana Paula Bouças, Andrea Carla Bauer

The maintenance of viable and functional pancreatic islets is crucial for successful islet transplantation from brain-dead donors. To overcome islet quality loss during culture, some studies have co-cultured islets with mesenchymal stem/stromal cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78f5f3805a7b916e3c9ec07f3a1241c3
https://europepmc.org/articles/PMC5345749/

Signaling mechanisms downstream of quinolinic acid targeting the cytoskeleton of rat striatal neurons and astrocytes

Autor: Paula Pierozan, Moacir Wajner, Regina Pessoa-Pureur, Karina Pires Reis, Fernanda Zamboni, Ariane Zamoner, Bárbara Ortiz de Lima, Ângela Krombauer Soska

Publikováno v: Experimental Neurology. 233(1):391-399

The studies of signaling mechanisms involved in the disruption of the cytoskeleton homeostasis were performed in a model of quinolinic acid (QUIN) neurotoxicity in vitro. This investigation focused on the phosphorylation level of intermediate filamen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75644aaf94760b60e6b5e1be355de1f6