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Endothelial‐derived von Willebrand factor accelerates fibrin clotting within engineered microvessels
Autor:
Samuel G. Rayner, Zackary Scholl, Christian J. Mandrycky, Junmei Chen, Karina N. LaValley, Peter J. Leary, William A. Altemeier, W. Conrad Liles, Dominic W. Chung, José A. López, Hongxia Fu, Ying Zheng
Publikováno v:
Journal of Thrombosis and Haemostasis. 20:1627-1637
Von Willebrand factor (VWF) is classically associated with primary hemostasis and platelet-rich arterial thromboses, but recently has also been implicated in fibrin clotting and venous thrombosis. Direct interaction between fibrin and VWF may mediate