High soluble HLA-DQB2 levels in posttransplant serum are associated with kidney graft dysfunction

Autor: Karina L Mine, Renato Marco, Tamiris R.F. Raimundo, Julia V. Ernesto, José O. Medina‐Pestana, Hélio Tedesco‐Silva, Maria Gerbase‐DeLima

Publikováno v: International journal of immunogeneticsREFERENCES. 49(2)

HLA-DQB2 is a gene of limited polymorphism, with unknown function that presents at least two transcript variants: v1, which encodes the full-length beta-chain, and v2, which lacks exon 4 and could give rise to a soluble protein. We previously showed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec0632a38808a1a9eddc8e01deb28bcb
https://pubmed.ncbi.nlm.nih.gov/35083872

Heightened expression of HLA-DQB1 and HLA-DQB2 in pre-implantation biopsies predicts poor late kidney graft function

Autor: Helio Tedesco-Silva, Maria Gerbase-DeLima, Larissa A. Salzedas, Erika F. Campos, Claudia Rosso Felipe, Tuíla B. Mourão, Karina L. Mine, Jose O. Medina-Pestana, Bruna L. Aguiar

Publikováno v: Human Immunology. 79:594-601

Accurate pre-transplant prediction of late graft function remains an unmet need in kidney transplantation. The aim of this study was to evaluate HLA genes expression levels in pre-implantation biopsies (PIB) of deceased donor kidneys as markers for l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c8938dd349b72adefd97e29e87ee30
https://doi.org/10.1016/j.humimm.2018.05.002

Unexpected links reflect the noise in networks

Autor: Xiaoxi Dong, Karina L. Mine, Anatoly Yambartsev, Andrey Morgun, Michael A. Perlin, Yevgeniy Kovchegov, Natalia Shulzhenko

Publikováno v: Biology Direct
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Background Gene covariation networks are commonly used to study biological processes. The inference of gene covariation networks from observational data can be challenging, especially considering the large number of players involved and the small num

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212eb6c8654c532167d94cfa69c26559
https://doi.org/10.1186/s13062-016-0155-0

HLA-DQB1 and -DRB1 alleles, cytokine polymorphisms and KIR gene frequencies in a population (Caucasian) from South East Brazil

Autor: Maria Gerbase-DeLima, G.F. Rampim, Andrey Morgun, Karina L. Mine, Natalia Shulzhenko, A. Godcalves-Primo

Publikováno v: Human Immunology. 65:879-882

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::45c2302fa98b611cb0429945c42f8d18
https://doi.org/10.1016/j.humimm.2004.08.017

Gene network reconstruction reveals cell cycle and antiviral genes as major drivers of cervical cancer

Autor: Andrey Morgun, Sylvia Michelina Fernandes Brenna, Ismael Dale Cotrim Guerreiro da Silva, Natalia Shulzhenko, Karina L. Mine, Tao Deng, Heidi Lyng, Natalia Volfovsky, Anatoly Yambartsev, Maria Gerbase-DeLima, Malin Lando, Sudhir Varma, Julisa Chamorro Lascasas Ribalta, Gerdine F. O. Sanson, Michael Bustin, Jeff Skinner, Carmen Carvalho, Polly Matzinger, Mark Rochman

Publikováno v: Nature communications
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Although human papillomavirus was identified as an aetiological factor in cervical cancer, the key human gene drivers of this disease remain unknown. Here we apply an unbiased approach integrating gene expression and chromosomal aberration data. In a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ab6163fd05c20e103fb10a3a0653a7
https://pubmed.ncbi.nlm.nih.gov/23651994