Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Karina Kulangara"'
Autor:
Javier Cortes, Eric P Winer, Oleg Lipatov, Seock‐Ah Im, Anthony Gonçalves, Eva Muñoz‐Couselo, Keun Seok Lee, Peter Schmid, Kenji Tamura, Laura Testa, Isabell Witzel, Shoichiro Ohtani, Stephanie Hund, Karina Kulangara, Vassiliki Karantza, Jaime A Mejia, Junshui Ma, Petar Jelinic, Lingkang Huang, Scott K Pruitt, Kenneth Emancipator
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 10, Iss 3, Pp n/a-n/a (2024)
Abstract The efficacy of pembrolizumab monotherapy versus chemotherapy increased with increasing programmed death ligand 1 (PD‐L1) expression, as quantified by combined positive score (CPS; PD‐L1 expression on both tumour cells and immune cells)
Externí odkaz:
https://doaj.org/article/42c035448af94e8fbfc51bd921ef67f3
Autor:
Jay Milo, Stephanie Hund, Angeliki Apostolaki, Siena Tabuena-Frolli, Karina Kulangara, Francisco Ponce, Lindsay Peltz, Chris La Placa, Monika Vilardo, Brittany Watts, Grant Toland, Alex Posch
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/80da51855d394fd2935f25e7b9e94f61
Autor:
Jonathan Juco, Kenneth Emancipator, Jay Milo, Christopher LaPlaca, Julia Hand, Stephanie Hund, Angeliki Apostolaki, Lindsay Guerrero, Bryce Portier, Siena Tabuena-Frolli, Karina Kulangara
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/7b9b4320493b422aa39f3364a327caac
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114698 (2014)
Mesenchymal stem/stromal cells respond to physical cues present in their microenvironment such as substrate elasticity, geometry, or topography with respect to morphology, proliferation, and differentiation. Although studies have demonstrated the rol
Externí odkaz:
https://doaj.org/article/d62175a867bf481f9dff6848d22c7221
Autor:
Andrew F Adler, Christopher L Grigsby, Karina Kulangara, Hong Wang, Ryohei Yasuda, Kam W Leong
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)
Transdifferentiation, where differentiated cells are reprogrammed into another lineage without going through an intermediate proliferative stem cell-like stage, is the next frontier of regenerative medicine. Wernig et al. first described the direct c
Externí odkaz:
https://doaj.org/article/956c4741f3364f53a0a5c1b811ea11c9
Autor:
Julia Hand, Francisco Ponce, Stephanie Hund, Lindsay Peltz, Micki Adams, Deanna Moquin, Megan Kalpakoff, Siena Tabuena-Frolli, Jay Milo, Angeliki Apostolaki, Karina Kulangara
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Greg Cherryholmes, Alexander Posch, Siena Tabuena-Frolli, Jesse Vasquez, Tiffany Evans, Chris La Placa, Kristopher Kersch, Angeliki Apostolaki, Jonathan Juco, Karina Kulangara
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Chris LaPlaca, Siena Tabuena-Frolli, Karina Kulangara, Jeanette Musser, Lindsay Peltz, Michael A. DiMaio, Rosanne Welcher, Angeliki Apostolaki, Charlotte Roach, Brittany Watts, Monika Vilardo, Stephanie Hund, Megan Kalpakoff
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology
Tumor heterogeneity may impact immunohistochemical (IHC) interpretation, thus potentially affecting decision making by treating oncologists for cancer patient management. Programmed cell death ligand-1 (PD-L1) IHC 22C3 pharmDx is a companion diagnost
Autor:
Fan Jin, Malinka Jansson, Burak Gumuscu, Michael A. DiMaio, Christopher J. La Placa, Brittany Watts, Joy Yang Ge, Monika D. Polewski, Monika Vilardo, Kenneth Emancipator, Karina Kulangara, Siena Tabuena-Frolli
Publikováno v:
Journal of Cancer Treatment and Diagnosis. 5:9-17
Objectives: FDA approval of PD-L1 IHC 22C3 pharmDx for use as an aid in identifying head and neck squamous cell carcinoma (HNSCC) patients for treatment with pembrolizumab was based on the results of rigorous analytical and clinical validation testin
Autor:
Karina Kulangara, Stephanie Hund, Siena Tabuena-Frolli, Jonathon Juco, Bryce Portier, Kenneth Emancipator, Darlene Krohn, Tiffany Evans
Publikováno v:
Cancer Research. 81:PS4-15
Background: The Tumor Proportion Score (TPS) and Combined Positive Score (CPS) scoring algorithms are used in conjunction with PD-L1 IHC 22C3 pharmDx for the immunohistochemical evaluation of PD-L1 in certain human cancer tissues; both algorithms inc