Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Karina Kubiak-Ossowska"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The structures of the Fc base of various IgG antibodies have been examined with a view to understanding how this region can be used to conjugate IgG to nanoparticles. The base structure is found to be largely consistent across a range of spe
Externí odkaz:
https://doaj.org/article/ef239524ae0b4060a8497467731b4148
Publikováno v:
ACS Omega, Vol 9, Iss 3, Pp 4123-4136 (2024)
Externí odkaz:
https://doaj.org/article/7296b7f0eaa14a99aea56b6b30a0bda1
Estimating Binding Energies of π-Stacked Aromatic Dimers Using Force Field-Driven Molecular Dynamics
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5783 (2024)
π–π stacking are omnipresent interactions, crucial in many areas of chemistry, and often studied using quantum chemical methods. Here, we report a simple and computationally efficient method of estimating the binding energies of stacked polycycli
Externí odkaz:
https://doaj.org/article/cd90d4dfbd89472ab6a7dd35ed951cf3
Autor:
Daniel Doveiko, Alan R. G. Martin, Vladislav Vyshemirsky, Simon Stebbing, Karina Kubiak-Ossowska, Olaf Rolinski, David J. S. Birch, Yu Chen
Publikováno v:
Materials, Vol 17, Iss 7, p 1686 (2024)
We investigate the nanometrology of sub-nanometre particle sizes in industrially manufactured sodium silicate liquors at high pH using time-resolved fluorescence anisotropy. Rather than the previous approach of using a single dye label, we investigat
Externí odkaz:
https://doaj.org/article/668fbba561dc4108ae08f577b424db1c
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Antibodies are well known for their high specificity that has enabled them to be of significant use in both therapeutic and diagnostic applications. Antibodies can recognize different antigens, including proteins, carbohydrates, peptides, nucleic aci
Externí odkaz:
https://doaj.org/article/b7cbf6c641b141e8ba31d276066e6fbc
Autor:
Mohammed A. H. Farouq, Karina Kubiak-Ossowska, Mohammed M. Al Qaraghuli, Valerie A. Ferro, Paul A. Mulheran
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4832 (2022)
Staphylococcus protein A (SpA) is found in the cell wall of Staphylococcus aureus bacteria. Its ability to bind to the constant Fc regions of antibodies means it is useful for antibody extraction, and further integration with inorganic materials can
Externí odkaz:
https://doaj.org/article/7def18df693e47639e4f7134d21c3a48
Publikováno v:
ACS Omega, Vol 3, Iss 11, Pp 16046-16056 (2018)
Externí odkaz:
https://doaj.org/article/1c342bc19aed461aad5f395a60057421
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5523 (2021)
Molecular dynamics (MD) simulations can provide a detailed view of molecule behaviour at an atomic level, which can be useful when attempting to interpret experiments or design new systems. The decapeptide gonadotrophin-releasing hormone I (GnRH-I) i
Externí odkaz:
https://doaj.org/article/4bd5572012c341b9966c2edd1431379c
Autor:
Evangelos Liamas, Karina Kubiak-Ossowska, Richard A. Black, Owen R.T. Thomas, Zhenyu J. Zhang, Paul A. Mulheran
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3321 (2018)
The effect of surface chemistry on the adsorption characteristics of a fibronectin fragment (FNIII8⁻10) was investigated using fully atomistic molecular dynamics simulations. Model surfaces were constructed to replicate self-assembled monolayers te
Externí odkaz:
https://doaj.org/article/69329c1d04174ff4ac955b9966cd6a18
Publikováno v:
Antibodies, Vol 7, Iss 3, p 21 (2018)
Monoclonal antibodies (mAbs) have revolutionized the biomedical field, directly influencing therapeutics and diagnostics in the biopharmaceutical industry, while continuing advances in computational efficiency have enabled molecular dynamics (MD) sim
Externí odkaz:
https://doaj.org/article/c7616e8f66934b9f9cb628506eab7baa