Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Karina Kawka"'
Publikováno v:
Membranes, Vol 12, Iss 4, p 359 (2022)
Efficient downstream processing represents a significant challenge in the rapidly developing field of therapeutic viruses. While it is known that the terminal sterile filtration step can be a major cause of product loss, there is little known about t
Externí odkaz:
https://doaj.org/article/5e0413f6e0c0411383c54d81bb0d8356
Autor:
Raja Ghosh, Karina Kawka, Umatheny Umatheva, Pedram Madadkar, Brian D. Lichty, Maria Fe C. Medina, Shabnam Shoaebargh, David R. Latulippe
Publikováno v:
Journal of Membrane Science. 579:351-358
Viruses are an emerging class of biotherapeutics with the potential to treat cancer, genetic, cardiovascular and other diseases. Their commercial success depends on cost-effective purification processes. Membrane chromatography processes offer great
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2ce401aabec17396ed96700668b3c3f
https://doi.org/10.1016/j.memsci.2019.02.056
https://doi.org/10.1016/j.memsci.2019.02.056
Autor:
Karina Kawka, A. Noelle Wilton, Eric J. Redmond, Maria Fe C. Medina, Brian D. Lichty, Raja Ghosh, David R. Latulippe
Publikováno v:
Biochemical Engineering Journal. 182:108417
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4a98ba9a3c3fb1f1cdf3ba4f740e26f
https://doi.org/10.1016/j.bej.2022.108417
https://doi.org/10.1016/j.bej.2022.108417
Autor:
A. Noelle Wilton, Brian D. Lichty, Karina Kawka, Maria Fe C. Medina, Raja Ghosh, David R. Latulippe, Pedram Madadkar
Publikováno v:
Separation and Purification Technology. 254:117503
High titer and purity levels are key requirements for virus-based cancer and gene therapy biopharmaceuticals. However, the task of removing enough host-cell DNA from therapeutic viruses in order to comply with the FDA’s 10 ng/dose limit is particul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de7ee8d615e7a157946dd61e492bb9db
https://doi.org/10.1016/j.seppur.2020.117503
https://doi.org/10.1016/j.seppur.2020.117503
Publikováno v:
Biotechnology and Bioengineering. 113:2131-2139
There is considerable interest in developing microscale (i.e., high-throughput) methods that enable multiple filtration experiments to be run in parallel with smaller sample amounts and thus reduce the overall required time and associated cost to run
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2cc047c5f4f535771755241aeb8bf96
https://doi.org/10.1002/bit.25975
https://doi.org/10.1002/bit.25975
Publikováno v:
Biotechnology and bioengineering. 113(10)
There is considerable interest in developing microscale (i.e., high-throughput) methods that enable multiple filtration experiments to be run in parallel with smaller sample amounts and thus reduce the overall required time and associated cost to run
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2638875e904a8667271f657f2ba5750f
https://pubmed.ncbi.nlm.nih.gov/27563852
https://pubmed.ncbi.nlm.nih.gov/27563852