Výsledky vyhledávání - "Karina A. Haas"

Essential requirements for the detection and degradation of invaders by the Haloferax volcanii CRISPR/Cas system I-B

Autor: Lisa-Katharina Maier, Susan Fischer, Eike Fischer, Jens Wöhnert, Britta Stoll, Elke Duchardt-Ferner, Karina A. Haas, Anita Marchfelder, Sita J. Lange, Rolf Backofen

Publikováno v: RNA Biology

To fend off foreign genetic elements, prokaryotes have developed several defense systems. The most recently discovered defense system, CRISPR/Cas, is sequence-specific, adaptive and heritable. The two central components of this system are the Cas pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93db7dffa76a96b9563585e6ea35cd73
http://europepmc.org/articles/PMC3737343

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Genome-wide identification of transcriptional start sites in the haloarchaeon Haloferax volcanii based on differential RNA-Seq (dRNA-Seq)

Autor: Rolf Hilker, Friedhelm Pfeiffer, Jörg Soppa, Daniela Näther-Schindler, Anita Marchfelder, Anke Becker, Matthias Hammelmann, Cynthia M. Sharma, Karina A. Haas, Julia Babski, Konrad U. Förstner

Publikováno v: BMC Genomics

Background Differential RNA-Seq (dRNA-Seq) is a recently developed method of performing primary transcriptome analyses that allows for the genome-wide mapping of transcriptional start sites (TSSs) and the identification of novel transcripts. Although

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8718486d1fd24a7ff641ef93bfc20bd
http://publikationen.ub.uni-frankfurt.de/files/45043/container.zip

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Carboxyl- and amino-functionalized polystyrene nanoparticles differentially affect the polarization profile of M1 and M2 macrophage subsets

Autor: Thomas Simmet, Karina A. Haas, Ann-Kathrin Fuchs, Tatiana Syrovets, Anna Musyanovych, Katharina Landfester, Cornelia Loos, Volker Mailänder

Macrophages are key regulators of innate and adaptive immune responses. Exposure to microenvironmental stimuli determines their polarization into proinflammatory M1 and anti-inflammatory M2 macrophages. M1 exhibit high expression of proinflammatory T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf473ddefc1168c09bf0be4b3299fb39
https://publica.fraunhofer.de/handle/publica/244124

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Differential Effects of Nanoparticle Surface-Functionalization on the Polarization Profiles of M1 and M2 Macrophages

Autor: Karina A. Haas, Thomas Simmet, Katharina Landfester, Anna Musyanovych, Cornelia Loos, Tatiana Syrovets, Volker Mailänder

Publikováno v: CIÊNCIAVITAE
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Exposure of macrophages to various cytokines initiates their polarization into either the classical proinflammatory M1 or the alternative anti-inflammatory M2 phenotype, which promotes wound healing and supports cancer growth. Here, we explored the e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d532d0da18baab13d7264441a9d62d
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000361722701154&KeyUID=WOS:000361722701154

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