Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Karina, Joppe"'
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
The homeostasis of iron is of fundamental importance in the central nervous system (CNS) to ensure biological processes such as oxygen transport, mitochondrial respiration or myelin synthesis. Dyshomeostasis and accumulation of iron can be observed d
Externí odkaz:
https://doaj.org/article/d839000ea7a249298622d0b3b47dcf42
Autor:
Stefan Becker, Shuyu Zhang, Karina Joppe, Anna-Elisa Roser, Hazem El DeBakey, Mathias Bähr, Mojan Parvaz, Lars Tatenhorst, Paul Lingor, Eleonora Carboni, Chi Wang Ip, Katarina Vogel-Mikuš, Markus Zweckstetter, Lucas Caldi Gomes
Publikováno v:
Journal of Neurochemistry
Journal of neurochemistry 159(3), 554-573 (2021). doi:10.1111/jnc.15461
Journal of neurochemistry 159(3), 554-573 (2021). doi:10.1111/jnc.15461
Regional iron accumulation and α‐synuclein (α‐syn) spreading pathology within the central nervous system are common pathological findings in Parkinson's disease (PD). Whereas iron is known to bind to α‐syn, facilitating its aggregation and r
Autor:
Karina, Joppe, Jan-David, Nicolas, Tilman A, Grünewald, Marina, Eckermann, Tim, Salditt, Paul, Lingor
Publikováno v:
Biomed Opt Express
In this work we use scanning X-ray microscopy to study the structure and elemental composition of neuromelanin-positive neurons in substantia nigra tissue of Parkinson patients (PD) and controls. A total of 53 neurons were analyzed with X-ray fluores