Comprehensive DNA methylation study identifies novel progression-related and prognostic markers for cutaneous melanoma

Autor: Jasper Wouters, Miguel Vizoso, Anna Martinez-Cardus, F. Javier Carmona, Olivier Govaere, Teresa Laguna, Jesuchristopher Joseph, Peter Dynoodt, Claudia Aura, Mona Foth, Roy Cloots, Karin van den Hurk, Balazs Balint, Ian G. Murphy, Enda W. McDermott, Kieran Sheahan, Karin Jirström, Bjorn Nodin, Girish Mallya-Udupi, Joost J. van den Oord, William M. Gallagher, Manel Esteller

Publikováno v: BMC Medicine, Vol 15, Iss 1, Pp 1-16 (2017)

Abstract Background Cutaneous melanoma is the deadliest skin cancer, with an increasing incidence and mortality rate. Currently, staging of patients with primary melanoma is performed using histological biomarkers such as tumor thickness and ulcerati

Externí odkaz: https://doaj.org/article/c8d582e4e15a4836ac917268c4fb77a8

Voorpret

Autor: Karin van den Hurk

Publikováno v: Laboratoriumgeneeskunde. 5:4-4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::267d4af9378fe977b930327896b52895
https://doi.org/10.24078/labgeneeskunde.2022.5.128833

Successful Treatment of Hereditary Folate Malabsorption With Intramuscular Folinic Acid

Autor: Charlotte M A Lubout, Malika Chegary, Nynke G.L. Jager, Susanna M. I. Goorden, Clara D.M. van Karnebeek, Silvana van Koningsbruggen, Bregje Jaeger, Karin van den Hurk

Publikováno v: Pediatric Neurology, 102, pp. 62-66
Pediatric Neurology, 102, 62-66
Pediatric neurology, 102, 62-66. Elsevier Inc.
Pediatric neurology, 102, 62-66. ELSEVIER SCIENCE INC

Item does not contain fulltext BACKGROUND: Hereditary folate malabsorption is a multisystem disease owing to biallelic variants in the gene encoding the proton-coupled folate transporter. Hereditary folate malabsorption is treated with folinic acid,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225277dbd7e40913865d3b1b371b1877
https://hdl.handle.net/2066/229209

Comprehensive DNA methylation study identifies novel progression-related and prognostic markers for cutaneous melanoma

Autor: Olivier Govaere, Teresa Laguna, Mona Foth, F. Javier Carmona, Karin Jirström, Balázs Bálint, Kieran Sheahan, Manel Esteller, William M. Gallagher, Joost van den Oord, Girish Mallya-Udupi, Anna Martínez-Cardús, Roy Cloots, Claudia Aura, Jasper Wouters, Jesuchristopher Joseph, Ian G. Murphy, Peter Dynoodt, Karin van den Hurk, Björn Nodin, Miguel Vizoso, Enda W. McDermott

Publikováno v: BMC Medicine, Vol 15, Iss 1, Pp 1-16 (2017)
BMC Medicine, 15:101. BioMed Central Ltd
BMC Medicine
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname

Background Cutaneous melanoma is the deadliest skin cancer, with an increasing incidence and mortality rate. Currently, staging of patients with primary melanoma is performed using histological biomarkers such as tumor thickness and ulceration. As di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5870f2cac57623879029b50371f98559
http://link.springer.com/article/10.1186/s12916-017-0851-3

High-throughput oncogene mutation profiling shows demographic differences in BRAF mutation rates among melanoma patients

Autor: Kieran Sheahan, Mairin Rafferty, Paul Donnellan, Elaine W. Kay, Owen MacEneaney, Derek G. Power, Julie Moran, Stephen P. Finn, Allan O'Keeffe, John Crown, Karin van den Hurk, Ian G. Murphy, Michelle Murphy, Balázs Bálint, Zsolt Orosz, Cynthia Heffron, Patrick O’Leary, William M. Gallagher, Joost van den Oord, Sinead Toomey, Clodagh M. McDermott, Cathal O'Brien, Louise Unwin, Padraic J. Regan, Ruben Yela, Dara M. FitzGerald, Robert Cummins, Enda W. McDermott, Bryan T. Hennessy

Publikováno v: Melanoma Research, 25(3), 189-199. LIPPINCOTT WILLIAMS & WILKINS

Because of advances in targeted therapies, the clinical evaluation of cutaneous melanoma is increasingly based on a combination of traditional histopathology and molecular pathology. Therefore, it is necessary to expand our knowledge of the molecular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::972ca0c773d198beee7caed45905902a
https://doi.org/10.1097/cmr.0000000000000149