Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Karin Zins"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 1825 (2023)
Telomerase reverse transcriptase (TERT) plays a key role in the maintenance of telomere DNA length. The rs10069690 single nucleotide variant, located in intron 4 of TERT, was found to be associated with telomere length and the risk of estrogen recept
Externí odkaz:
https://doaj.org/article/99d2345cc9a845cd8685ca8402ddbd04
Autor:
Karin Zins, Barbara Frech, Eva Taubenschuss, Christian Schneeberger, Dietmar Abraham, Martin Schreiber
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 12, Pp 29643-29653 (2015)
Like other RECQ helicases, WRN/RECQL2 plays a crucial role in DNA replication and the maintenance of genome stability. Inactivating mutations in RECQL2 lead to Werner syndrome, a rare autosomal disease associated with premature aging and an increased
Externí odkaz:
https://doaj.org/article/5c5be7d810c244c2b237681fafe67c6f
Autor:
Karin Zins, Dietmar Abraham
Publikováno v:
Cancers, Vol 12, Iss 2, p 342 (2020)
Macrophages form a major component of the leukocyte infiltrate in solid tumors and it has become increasingly clear that tumor-associated macrophages (TAMs) have tumor-promoting effects within the stroma [...]
Externí odkaz:
https://doaj.org/article/3a92b32d13f1421da0c42c7e7893aa30
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 1, Pp 712-724 (2014)
The CYP19 gene encodes aromatase, an enzyme catalyzing the conversion of androgens to estrogens. Studies analyzing associations between single nucleotide polymorphisms in CYP19 and breast cancer risk have shown inconsistent results. The rs10046 polym
Externí odkaz:
https://doaj.org/article/272cc54f396e46e5913ed2b2f94b0d13
Autor:
Karin Zins, Jiri Pomyje, Erhard Hofer, Dietmar Abraham, Trevor Lucas, Seyedhossein Aharinejad
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 1, Pp 1538-1553 (2014)
The early growth response transcription factor Egr-1 controls cell specific responses to proliferation, differentiation and apoptosis. Expression of Egr-1 and downstream transcription is closely controlled and cell specific upregulation induced by pr
Externí odkaz:
https://doaj.org/article/e6f7244a6e21424997c73a4b5c5bd647
Autor:
Dietmar Abraham, Seyedhossein Aharinejad, Mouldy Sioud, Trevor Lucas, Anita Thomas, Karin Zins
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 9, Pp 17958-17971 (2013)
The growth and vascularization of prostate cancer is dependent on interactions between cancer cells and supporting stromal cells. The primary stromal cell type found in prostate tumors is the carcinoma-associated fibroblast, which produces placental
Externí odkaz:
https://doaj.org/article/0764318a4fdf46368c42fc1e31edf540
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 10, p 1613 (2016)
Neuroblastoma (NB) is the most common extracranial solid tumor of childhood and is a rapidly growing, highly-vascularized cancer. NBs frequently express angiogenic factors and high tumor angiogenesis has been associated with poor outcomes. Placental
Externí odkaz:
https://doaj.org/article/e7df4b7add464c41a7903ee70b718527
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74924 (2013)
Deregulated Rho GTPases Rac1 and Cdc42 have been discovered in various tumors, including prostate and Rac protein expression significantly increases in prostate cancer. The Rac and Cdc42 pathways promote the uncontrolled proliferation, invasion and m
Externí odkaz:
https://doaj.org/article/37ad2db3a49b41a8a22a2c324bd52c3e
The interplay between malignant and stromal cells is essential in tumorigenesis. We have previously shown that colony-stimulating factor (CSF)-1, matrix metalloprotease (MMP)-2, and vascular endothelial growth factor (VEGF)-A production by stromal ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a8097761f302ad13d6c23041f2da56
https://doi.org/10.1158/0008-5472.c.6495120.v1
https://doi.org/10.1158/0008-5472.c.6495120.v1
Supplementary Figure 2 from Colon Cancer Cell–Derived Tumor Necrosis Factor-α Mediates the Tumor Growth–Promoting Response in Macrophages by Up-regulating the Colony-Stimulating Factor-1 Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a14b85c56148b4cbe3a1b0e6623da8be
https://doi.org/10.1158/0008-5472.22366386.v1
https://doi.org/10.1158/0008-5472.22366386.v1