Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Karin Willeit"'
Autor:
Amand F. Schmidt, Michael V. Holmes, David Preiss, Daniel I. Swerdlow, Spiros Denaxas, Ghazaleh Fatemifar, Rupert Faraway, Chris Finan, Dennis Valentine, Zammy Fairhurst-Hunter, Fernando Pires Hartwig, Bernardo Lessa Horta, Elina Hypponen, Christine Power, Max Moldovan, Erik van Iperen, Kees Hovingh, Ilja Demuth, Kristina Norman, Elisabeth Steinhagen-Thiessen, Juri Demuth, Lars Bertram, Christina M. Lill, Stefan Coassin, Johann Willeit, Stefan Kiechl, Karin Willeit, Dan Mason, John Wright, Richard Morris, Goya Wanamethee, Peter Whincup, Yoav Ben-Shlomo, Stela McLachlan, Jackie F. Price, Mika Kivimaki, Catherine Welch, Adelaida Sanchez-Galvez, Pedro Marques-Vidal, Andrew Nicolaides, Andrie G. Panayiotou, N. Charlotte Onland-Moret, Yvonne T. van der Schouw, Giuseppe Matullo, Giovanni Fiorito, Simonetta Guarrera, Carlotta Sacerdote, Nicholas J. Wareham, Claudia Langenberg, Robert A. Scott, Jian’an Luan, Martin Bobak, Sofia Malyutina, Andrzej Pająk, Ruzena Kubinova, Abdonas Tamosiunas, Hynek Pikhart, Niels Grarup, Oluf Pedersen, Torben Hansen, Allan Linneberg, Tine Jess, Jackie Cooper, Steve E. Humphries, Murray Brilliant, Terrie Kitchner, Hakon Hakonarson, David S. Carrell, Catherine A. McCarty, Kirchner H. Lester, Eric B. Larson, David R. Crosslin, Mariza de Andrade, Dan M. Roden, Joshua C. Denny, Cara Carty, Stephen Hancock, John Attia, Elizabeth Holliday, Rodney Scott, Peter Schofield, Martin O’Donnell, Salim Yusuf, Michael Chong, Guillaume Pare, Pim van der Harst, M. Abdullah Said, Ruben N. Eppinga, Niek Verweij, Harold Snieder, Lifelines Cohort authors, Tim Christen, D. O. Mook-Kanamori, the ICBP Consortium, Stefan Gustafsson, Lars Lind, Erik Ingelsson, Raha Pazoki, Oscar Franco, Albert Hofman, Andre Uitterlinden, Abbas Dehghan, Alexander Teumer, Sebastian Baumeister, Marcus Dörr, Markus M. Lerch, Uwe Völker, Henry Völzke, Joey Ward, Jill P. Pell, Tom Meade, Ingrid E. Christophersen, Anke H. Maitland-van der Zee, Ekaterina V. Baranova, Robin Young, Ian Ford, Archie Campbell, Sandosh Padmanabhan, Michiel L. Bots, Diederick E. Grobbee, Philippe Froguel, Dorothée Thuillier, Ronan Roussel, Amélie Bonnefond, Bertrand Cariou, Melissa Smart, Yanchun Bao, Meena Kumari, Anubha Mahajan, Jemma C. Hopewell, Sudha Seshadri, the METASTROKE Consortium of the ISGC, Caroline Dale, Rui Providencia E. Costa, Paul M. Ridker, Daniel I. Chasman, Alex P. Reiner, Marylyn D. Ritchie, Leslie A. Lange, Alex J. Cornish, Sara E. Dobbins, Kari Hemminki, Ben Kinnersley, Marc Sanson, Karim Labreche, Matthias Simon, Melissa Bondy, Philip Law, Helen Speedy, James Allan, Ni Li, Molly Went, Niels Weinhold, Gareth Morgan, Pieter Sonneveld, Björn Nilsson, Hartmut Goldschmidt, Amit Sud, Andreas Engert, Markus Hansson, Harry Hemingway, Folkert W. Asselbergs, Riyaz S. Patel, Brendan J. Keating, Naveed Sattar, Richard Houlston, Juan P. Casas, Aroon D. Hingorani
Publikováno v:
BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background We characterised the phenotypic consequence of genetic variation at the PCSK9 locus and compared findings with recent trials of pharmacological inhibitors of PCSK9. Methods Published and individual participant level data (300,000+
Externí odkaz:
https://doaj.org/article/6496ec7ef17e440a938a2e70da19e20c
Autor:
Peter Willeit, Thomas Toell, Christian Boehme, Stefan Krebs, Lukas Mayer, Clemens Lang, Lisa Seekircher, Lena Tschiderer, Karin Willeit, Gerhard Rumpold, Gudrun Schoenherr, Andrea Griesmacher, Julia Ferrari, Michael Knoflach, Wilfried Lang, Stefan Kiechl, Johann Willeit
Publikováno v:
EClinicalMedicine, Vol 25, Iss , Pp 100476- (2020)
Background: Patients with ischaemic stroke or transient ischaemic attack (TIA) are at high risk of recurrent stroke and other cardiovascular diseases and commonly suffer from reduced quality of life. We aimed to determine whether the disease manageme
Externí odkaz:
https://doaj.org/article/41ab5946a48a4fee8d4a79019c79e2e8
Autor:
Xu Yang, Wei Yang, David G. McVey, Guojun Zhao, Jinfu Hu, Robin N. Poston, Meixia Ren, Karin Willeit, Stefan Coassin, Johann Willeit, Thomas R. Webb, Nilesh J. Samani, Manuel Mayr, Stefan Kiechl, Shu Ye
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 4 (2020)
Background Genome‐wide association studies have shown an association between the single‐nucleotide polymorphism rs17514846 on chromosome 15q26.1 and coronary artery disease susceptibility. The underlying biological mechanism is, however, not full
Externí odkaz:
https://doaj.org/article/837636ef05be4041bef1817b8e6f444d
Autor:
Thomas Toell, Christian Boehme, Lukas Mayer, Stefan Krebs, Clemens Lang, Karin Willeit, Barbara Prantl, Michael Knoflach, Gerhard Rumpold, Gudrun Schoenherr, Andrea Griesmacher, Peter Willeit, Julia Ferrari, Wilfried Lang, Stefan Kiechl, Johann Willeit
Publikováno v:
BMC Neurology, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Patients with ischaemic stroke or transient ischaemic attack (TIA) are at high risk of future cardiovascular events. Despite compelling evidence about the efficacy of secondary prevention, a substantial gap exists between risk fac
Externí odkaz:
https://doaj.org/article/57458bc02b6f4bed9f5b031c02fc40ce
Autor:
Wilfried Lang, Stefan Krebs, Andrea Griesmacher, Lisa Seekircher, Peter Willeit, Lukas Mayer, Stefan Kiechl, Gerhard Rumpold, Thomas Toell, Karin Willeit, Clemens Lang, Lena Tschiderer, Johann Willeit, Christian Boehme, Michael Knoflach, Julia Ferrari, Gudrun Schoenherr
Publikováno v:
Willeit, Peter; Toell, Thomas; Boehme, Christian; Krebs, Stefan; Mayer, Lukas; Lang, Clemens; Seekircher, Lisa; Tschiderer, Lena; Willeit, Karin; Rumpold, Gerhard; Schoenherr, Gudrun; Griesmacher, Andrea; Ferrari, Julia; Knoflach, Michael; Lang, Wilfried; Kiechl, Stefan; Willeit, Johann (2020). STROKE-CARD care to prevent cardiovascular events and improve quality of life after acute ischaemic stroke or TIA: A randomised clinical trial. EClinicalMedicine, 25, p. 100476. Elsevier 10.1016/j.eclinm.2020.100476
EClinicalMedicine
EClinicalMedicine, Vol 25, Iss, Pp 100476-(2020)
EClinicalMedicine
EClinicalMedicine, Vol 25, Iss, Pp 100476-(2020)
Background Patients with ischaemic stroke or transient ischaemic attack (TIA) are at high risk of recurrent stroke and other cardiovascular diseases and commonly suffer from reduced quality of life. We aimed to determine whether the disease managemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9df74ec1ac08b4cba534b8ae8418a1e
Autor:
Meixia Ren, Jinfu Hu, Stefan Kiechl, David G. McVey, Shu Ye, Manuel Mayr, Guojun Zhao, Robin N. Poston, Nilesh J. Samani, Karin Willeit, Tom R. Webb, Wei Yang, Johann Willeit, Xu Yang, Stefan Coassin
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Yang, Xu; Yang, Wei; McVey, David G; Zhao, Guojun; Hu, Jinfu; Poston, Robin N; Ren, Meixia; Willeit, Karin; Coassin, Stefan; Willeit, Johann; Webb, Thomas R; Samani, Nilesh J; Mayr, Manuel; Kiechl, Stefan; Ye, Shu (2020). FURIN Expression in Vascular Endothelial Cells Is Modulated by a Coronary Artery Disease-Associated Genetic Variant and Influences Monocyte Transendothelial Migration. Journal of the American Heart Association, 9(4), e014333. American Heart Association 10.1161/JAHA.119.014333
Yang, Xu; Yang, Wei; McVey, David G; Zhao, Guojun; Hu, Jinfu; Poston, Robin N; Ren, Meixia; Willeit, Karin; Coassin, Stefan; Willeit, Johann; Webb, Thomas R; Samani, Nilesh J; Mayr, Manuel; Kiechl, Stefan; Ye, Shu (2020). FURIN Expression in Vascular Endothelial Cells Is Modulated by a Coronary Artery Disease-Associated Genetic Variant and Influences Monocyte Transendothelial Migration. Journal of the American Heart Association, 9(4), e014333. American Heart Association 10.1161/JAHA.119.014333
Background Genome‐wide association studies have shown an association between the single‐nucleotide polymorphism rs17514846 on chromosome 15q26.1 and coronary artery disease susceptibility. The underlying biological mechanism is, however, not full
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::843ac914f5cf84b4e1796b6c23000701
Autor:
Hermann Stuppner, Johann Willeit, Raimund Pechlaner, Friedrich Oberhollenzer, Slaven Stekovic, Monika Chmelíková, Ludmilla Kedenko, Guido Kroemer, Frank Madeo, Barbara Mairhofer, Karin Willeit, Herbert Tilg, Markus Gartner, Marlene Notdurfter, Peter Willeit, Siegfried Weger, Christoph Ruckenstuhl, Manuel Mayr, Bernhard Iglseder, Stefan Kiechl, Bernhard Paulweber, Tobias Eisenberg, Philipp Werner
Publikováno v:
The American Journal of Clinical Nutrition. 108:371-380
Background Spermidine administration is linked to increased survival in several animal models. Objective The aim of this study was to test the potential association between spermidine content in diet and mortality in humans. Design This prospective c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad917170fd1c4feb323951a0eb4928b3
https://doi.org/10.1093/ajcn/nqy102
https://doi.org/10.1093/ajcn/nqy102
Autor:
Thomas Toell, Karin Willeit, Christian Boehme, Philipp Fuchs, Lukas Mayer, Stefan Krebs, Wolfgang Prokop, Wilfried Lang, Julia Ferrari, Stefan Kiechl, Clemens Lang, Barbara Prantl, Raimund Pechlaner, Andrea Griesmacher, Johann Willeit, Michael Knoflach
Publikováno v:
European Journal of Neurology. 25:260-267
Background and aims Identification of patients with familial hypercholesterolemia (FH) is a prerequisite for the appropriate management of their excess cardiovascular risk. It is currently unknown how many patients with acute ischemic stroke or trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51bde4588949d3a0662107e74498cc53
https://doi.org/10.1111/ene.13485
https://doi.org/10.1111/ene.13485
Autor:
Ruifang Lu, Philipp Skroblin, Gerard Pasterkamp, Sarah R. Langley, Catherine M. Shanahan, Peter Willeit, Mariette Lengquist, Chris Molenaar, Joseph Shalhoub, Manuel Mayr, Alexander N. Kapustin, Ljubica Perisic Matic, Karin Willeit, Ulf Hedin, Claudia Monaco, Johann Willeit, Athanasios Didangelos, Bernhard Iglseder, Temo Barwari, Stefan Kiechl, Xiaoke Yin, Bernhard Paulweber, Javier Barallobre-Barreiro, Alun H. Davies, Ludmilla Kedenko, Gonca Suna, Gregor Rungger
Publikováno v:
The Journal of Clinical Investigation
Journal of Clinical Investigation, 127(4), 1546. The American Society for Clinical Investigation
Langley, S R, Willeit, K, Didangelos, A, Matic, L P, Skroblin, P, Barallobre-barreiro, J, Lengquist, M, Rungger, G, Kapustin, A, Kedenko, L, Molenaar, C, Lu, R, Barwari, T, Suna, G, Yin, X, Iglseder, B, Paulweber, B, Willeit, P, Shalhoub, J, Pasterkamp, G, Davies, A H, Monaco, C, Hedin, U, Shanahan, C M, Willeit, J, Kiechl, S & Mayr, M 2017, ' Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques ', Journal of Clinical Investigation, vol. 127, no. 4, pp. 1546-1560 . https://doi.org/10.1172/JCI86924
Journal of Clinical Investigation, 127(4), 1546. The American Society for Clinical Investigation
Langley, S R, Willeit, K, Didangelos, A, Matic, L P, Skroblin, P, Barallobre-barreiro, J, Lengquist, M, Rungger, G, Kapustin, A, Kedenko, L, Molenaar, C, Lu, R, Barwari, T, Suna, G, Yin, X, Iglseder, B, Paulweber, B, Willeit, P, Shalhoub, J, Pasterkamp, G, Davies, A H, Monaco, C, Hedin, U, Shanahan, C M, Willeit, J, Kiechl, S & Mayr, M 2017, ' Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques ', Journal of Clinical Investigation, vol. 127, no. 4, pp. 1546-1560 . https://doi.org/10.1172/JCI86924
Background The identification of patients with high-risk atherosclerotic plaques prior to the manifestation of clinical events remains challenging. Recent findings question histology- and imaging-based definitions of the "vulnerable plaque," necessit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06bd6507360d0b7346be45c1a632f84c
https://doi.org/10.1172/jci86924
https://doi.org/10.1172/jci86924
Autor:
Chris Finan, Yoav Ben-Shlomo, Eric B. Larson, Tine Jess, Richard W Morris, Daniel I. Chasman, Fernando Pires Hartwig, Catherine Welch, Rodney J. Scott, Helen E. Speedy, Andrzej Pajak, Raha Pazoki, André G. Uitterlinden, Torben Hansen, Marc Sanson, Hakon Hakonarson, Claudia Langenberg, Joey Ward, John Wright, Dorothée Thuillier, Ben Kinnersley, Diederick E. Grobbee, Yvonne T. van der Schouw, Pieter Sonneveld, Michiel L. Bots, Harold Snieder, Karim Labreche, Dan M. Roden, Archie Campbell, Melissa C. Smart, Christine Power, Pim van der Harst, Amélie Bonnefond, Ingrid E. Christophersen, Riyaz S. Patel, Uwe Völker, Stephen Hancock, Niels Grarup, Dennis O. Mook-Kanamori, Mariza de Andrade, Caroline Dale, N. Charlotte Onland-Moret, David R. Crosslin, Meena Kumari, Erik Ingelsson, Michael V. Holmes, Spiros Denaxas, Sudha Seshadri, Kees Hovingh, Marcus Dörr, Paul M. Ridker, Stefan Coassin, Albert Hofman, Andrew N. Nicolaides, Oluf Pedersen, Philippe Froguel, Simonetta Guarrera, Murray H. Brilliant, Sara E. Dobbins, Salim Yusuf, Kari Hemminki, Erik P A Van Iperen, Abbas Dehghan, Jill P. Pell, Alexander Teumer, Peter W. Schofield, Aroon D. Hingorani, Dan Mason, Amand F. Schmidt, Rui Bebiano Da Providencia E Costa, James M. Allan, Leslie A. Lange, Niels Weinhold, Stefan Gustafsson, Jackie F. Price, Mika Kivimäki, Hynek Pikhart, Kirchner H. Lester, Lars Lind, Philip J. Law, Cara L. Carty, David Preiss, Richard S. Houlston, Robin Young, Tom W. Meade, Martin O'Donnell, Alexander P. Reiner, Ni Li, Oscar H. Franco, Zammy Fairhurst-Hunter, Ronan Roussel, Tim Christen, Ilja Demuth, David Carrell, Catherine A. McCarty, Juan P. Casas, Johann Willeit, Peter H. Whincup, Stela McLachlan, Adelaida Sanchez-Galvez, Hartmut Goldschmidt, Guillaume Paré, Harry Hemingway, Anubha Mahajan, Elisabeth Steinhagen-Thiessen, Elizabeth G. Holliday, Giuseppe Matullo, Henry Völzke, Ian Ford, Martin Bobak, Pedro Marques-Vidal, Bertrand Cariou, Bernardo L. Horta, Melissa L. Bondy, Goya Wanamethee, Naveed Sattar, Steve E. Humphries, Marylyn D. Ritchie, Kristina Norman, Carlotta Sacerdote, Giovanni Fiorito, Sebastian E. Baumeister, Amit Sud, Dennis Valentine, Andreas Engert, Juri Demuth, Rupert Faraway, Abdonas Tamosiunas, Andrie G. Panayiotou, Terrie Kitchner, Lars Bertram, Sandosh Padmanabhan, Sofia Malyutina, Anke H. Maitland-van der Zee, Alex J. Cornish, Joshua C. Denny, Jian'an Luan, Robert A. Scott, Daniel I. Swerdlow, John Attia, Karin Willeit, Gareth J. Morgan, Michael Chong, Ruben N. Eppinga, Elina Hyppönen, Ekaterina V. Baranova, Jackie A. Cooper, Ghazaleh Fatemifar, Niek Verweij, Max Moldovan, Brendan J. Keating, M. Abdullah Said, Markus M. Lerch, Christina M. Lill, Markus Hansson, Jemma C. Hopewell, Björn Nilsson, Folkert W. Asselbergs, Ruzena Kubinova, Molly Went, Nicholas J. Wareham, Stefan Kiechl, Yanchun Bao, Allan Linneberg, Matthias Simon
Publikováno v:
BMC Cardiovascular Disorders, 19(1). BMC
Schmidt, Amand F; Holmes, Michael V; Preiss, David; Swerdlow, Daniel I; Denaxas, Spiros; Fatemifar, Ghazaleh; Faraway, Rupert; Finan, Chris; Valentine, Dennis; Fairhurst-Hunter, Zammy; Hartwig, Fernando Pires; Horta, Bernardo Lessa; Hypponen, Elina; Power, Christine; Moldovan, Max; van Iperen, Erik; Hovingh, Kees; Demuth, Ilja; Norman, Kristina; Steinhagen-Thiessen, Elisabeth; ... (2019). Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9. BMC cardiovascular disorders, 19(1), p. 240. BioMed Central 10.1186/s12872-019-1187-z
BMC cardiovascular disorders, 19(1):240. BioMed Central
BMC cardiovascular disorders, London : BioMed Central, 2019, vol. 19, no. 1, 240, p. 1-10
BMC Cardiovascular Disorders
BMC Cardiovascular Disorders, 19(1). BioMed Central
BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-10 (2019)
Schmidt, A F, Holmes, M V, Preiss, D, Swerdlow, D I, Denaxas, S, Fatemifar, G, Faraway, R, Finan, C, Valentine, D, Fairhurst-Hunter, Z, McLachlan, S & Price, J 2019, ' Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9 ', Bmc cardiovascular disorders . https://doi.org/10.1186/s12872-019-1187-z
BMC Cardiovascular Disorders, 19(1):240. BioMed Central Ltd.
Schmidt, A F, Holmes, M V, Preiss, D, Swerdlow, D I, Denaxas, S, Fatemifar, G, Faraway, R, Finan, C, Valentine, D, Fairhurst-Hunter, Z, Hartwig, F P, Horta, B L, Hypponen, E, Power, C, Moldovan, M, Van Iperen, E, Hovingh, K, Demuth, I, Norman, K, Steinhagen-Thiessen, E, Demuth, J, Bertram, L, Lill, C M, Coassin, S, Willeit, J, Kiechl, S, Willeit, K, Mason, D, Wright, J, Morris, R, Wanamethee, G, Whincup, P, Ben-Shlomo, Y, McLachlan, S, Price, J F, Kivimaki, M, Welch, C, Sanchez-Galvez, A, Marques-Vidal, P, Nicolaides, A, Panayiotou, A G, Onland-Moret, N C, Van Der Schouw, Y T, Matullo, G, Fiorito, G, Guarrera, S, Sacerdote, C, Wareham, N J, Langenberg, C, Scott, R A, Luan, JA, Bobak, M, Malyutina, S, Pajak, A, Kubinova, R, Tamosiunas, A, Pikhart, H, Grarup, N, Pedersen, O, Hansen, T, Linneberg, A, Jess, T, Cooper, J, Humphries, S E, Brilliant, M, Kitchner, T, Hakonarson, H, Carrell, D S, McCarty, C A, Lester, K H, Larson, E B, Crosslin, D R, De Andrade, M, Roden, D M, Denny, J C, Carty, C, Hancock, S, Attia, J, Holliday, E, Scott, R, Schofield, P, O'Donnell, M, Yusuf, S, Chong, M, Pare, G, Van Der Harst, P, Said, M A, Eppinga, R N, Verweij, N, Snieder, H, Christen, T, Mook-Kanamori, D O, Gustafsson, S, Lind, L, Ingelsson, E, Pazoki, R, Franco, O, Hofman, A, Uitterlinden, A, Dehghan, A, Teumer, A, Baumeister, S, Dörr, M, Lerch, M M, Völker, U, Völzke, H, Ward, J, Pell, J P, Meade, T, Christophersen, I E, Maitland-Van Der Zee, A H, Baranova, E V, Young, R, Ford, I, Campbell, A, Padmanabhan, S, Bots, M L, Grobbee, D E, Froguel, P, Thuillier, D, Roussel, R, Bonnefond, A, Cariou, B, Smart, M, Bao, Y, Kumari, M, Mahajan, A, Hopewell, J C, Seshadri, S, Dale, C, Costa, R P E, Ridker, P M, Chasman, D I, Reiner, A P, Ritchie, M D, Lange, L A, Cornish, A J, Dobbins, S E, Hemminki, K, Kinnersley, B, Sanson, M, Labreche, K, Simon, M, Bondy, M, Law, P, Speedy, H, Allan, J, Li, N, Went, M, Weinhold, N, Morgan, G, Sonneveld, P, Nilsson, B, Goldschmidt, H, Sud, A, Engert, A, Hansson, M, Hemingway, H, Asselbergs, F W, Patel, R S, Keating, B J, Sattar, N, Houlston, R, Casas, J P & Hingorani, A D 2019, ' Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9 ', BMC Cardiovascular Disorders, vol. 19, no. 1, 240 . https://doi.org/10.1186/s12872-019-1187-z
Schmidt, Amand F; Holmes, Michael V; Preiss, David; Swerdlow, Daniel I; Denaxas, Spiros; Fatemifar, Ghazaleh; Faraway, Rupert; Finan, Chris; Valentine, Dennis; Fairhurst-Hunter, Zammy; Hartwig, Fernando Pires; Horta, Bernardo Lessa; Hypponen, Elina; Power, Christine; Moldovan, Max; van Iperen, Erik; Hovingh, Kees; Demuth, Ilja; Norman, Kristina; Steinhagen-Thiessen, Elisabeth; ... (2019). Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9. BMC cardiovascular disorders, 19(1), p. 240. BioMed Central 10.1186/s12872-019-1187-z
BMC cardiovascular disorders, 19(1):240. BioMed Central
BMC cardiovascular disorders, London : BioMed Central, 2019, vol. 19, no. 1, 240, p. 1-10
BMC Cardiovascular Disorders
BMC Cardiovascular Disorders, 19(1). BioMed Central
BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-10 (2019)
Schmidt, A F, Holmes, M V, Preiss, D, Swerdlow, D I, Denaxas, S, Fatemifar, G, Faraway, R, Finan, C, Valentine, D, Fairhurst-Hunter, Z, McLachlan, S & Price, J 2019, ' Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9 ', Bmc cardiovascular disorders . https://doi.org/10.1186/s12872-019-1187-z
BMC Cardiovascular Disorders, 19(1):240. BioMed Central Ltd.
Schmidt, A F, Holmes, M V, Preiss, D, Swerdlow, D I, Denaxas, S, Fatemifar, G, Faraway, R, Finan, C, Valentine, D, Fairhurst-Hunter, Z, Hartwig, F P, Horta, B L, Hypponen, E, Power, C, Moldovan, M, Van Iperen, E, Hovingh, K, Demuth, I, Norman, K, Steinhagen-Thiessen, E, Demuth, J, Bertram, L, Lill, C M, Coassin, S, Willeit, J, Kiechl, S, Willeit, K, Mason, D, Wright, J, Morris, R, Wanamethee, G, Whincup, P, Ben-Shlomo, Y, McLachlan, S, Price, J F, Kivimaki, M, Welch, C, Sanchez-Galvez, A, Marques-Vidal, P, Nicolaides, A, Panayiotou, A G, Onland-Moret, N C, Van Der Schouw, Y T, Matullo, G, Fiorito, G, Guarrera, S, Sacerdote, C, Wareham, N J, Langenberg, C, Scott, R A, Luan, JA, Bobak, M, Malyutina, S, Pajak, A, Kubinova, R, Tamosiunas, A, Pikhart, H, Grarup, N, Pedersen, O, Hansen, T, Linneberg, A, Jess, T, Cooper, J, Humphries, S E, Brilliant, M, Kitchner, T, Hakonarson, H, Carrell, D S, McCarty, C A, Lester, K H, Larson, E B, Crosslin, D R, De Andrade, M, Roden, D M, Denny, J C, Carty, C, Hancock, S, Attia, J, Holliday, E, Scott, R, Schofield, P, O'Donnell, M, Yusuf, S, Chong, M, Pare, G, Van Der Harst, P, Said, M A, Eppinga, R N, Verweij, N, Snieder, H, Christen, T, Mook-Kanamori, D O, Gustafsson, S, Lind, L, Ingelsson, E, Pazoki, R, Franco, O, Hofman, A, Uitterlinden, A, Dehghan, A, Teumer, A, Baumeister, S, Dörr, M, Lerch, M M, Völker, U, Völzke, H, Ward, J, Pell, J P, Meade, T, Christophersen, I E, Maitland-Van Der Zee, A H, Baranova, E V, Young, R, Ford, I, Campbell, A, Padmanabhan, S, Bots, M L, Grobbee, D E, Froguel, P, Thuillier, D, Roussel, R, Bonnefond, A, Cariou, B, Smart, M, Bao, Y, Kumari, M, Mahajan, A, Hopewell, J C, Seshadri, S, Dale, C, Costa, R P E, Ridker, P M, Chasman, D I, Reiner, A P, Ritchie, M D, Lange, L A, Cornish, A J, Dobbins, S E, Hemminki, K, Kinnersley, B, Sanson, M, Labreche, K, Simon, M, Bondy, M, Law, P, Speedy, H, Allan, J, Li, N, Went, M, Weinhold, N, Morgan, G, Sonneveld, P, Nilsson, B, Goldschmidt, H, Sud, A, Engert, A, Hansson, M, Hemingway, H, Asselbergs, F W, Patel, R S, Keating, B J, Sattar, N, Houlston, R, Casas, J P & Hingorani, A D 2019, ' Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9 ', BMC Cardiovascular Disorders, vol. 19, no. 1, 240 . https://doi.org/10.1186/s12872-019-1187-z
BackgroundWe characterised the phenotypic consequence of genetic variation at the PCSK9 locus and compared findings with recent trials of pharmacological inhibitors of PCSK9.MethodsPublished and individual participant level data (300,000+ participant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8a7b3e5163aceb6019624e27507e6b
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-401186
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-401186