Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Karin Weijers"'
Autor:
Margaretha G.M. Roemer, Tim van de Brug, Erik Bosch, Daniella Berry, Nathalie Hijmering, Phylicia Stathi, Karin Weijers, Jeannette Doorduijn, Jacoline Bromberg, Mark van de Wiel, Bauke Ylstra, Daphne de Jong, Yongsoo Kim
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107331- (2023)
Summary: To understand the clinical significance of the tumor microenvironment (TME), it is essential to study the interactions between malignant and non-malignant cells in clinical specimens. Here, we established a computational framework for a mult
Externí odkaz:
https://doaj.org/article/b93f9e05d3bf4bc2823b75234a29a36d
Autor:
Willem E Corver, Dina Ruano, Karin Weijers, Wietske C E den Hartog, Merlijn P van Nieuwenhuizen, Noel de Miranda, Ronald van Eijk, Anneke Middeldorp, Ekaterina S Jordanova, Jan Oosting, Ellen Kapiteijn, Guido Hovens, Jan Smit, Tom van Wezel, Hans Morreau
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38287 (2012)
Recurrent non-medullary thyroid carcinoma (NMTC) is a rare disease. We initially characterized 27 recurrent NMTC: 13 papillary thyroid cancers (PTC), 10 oncocytic follicular carcinomas (FTC-OV), and 4 non-oncocytic follicular carcinomas (FTC). A vali
Externí odkaz:
https://doaj.org/article/aaf6514059d6488988d616a175c73ad8
Autor:
Margaretha G.M. Roemer, Tim van de Brug, Erik Bosch, Daniella Berry, Nathalie Hijmering, Phylicia Stathi, Karin Weijers, Jeannette Doorduijn, Jacoline Bromberg, Mark van de Wiel, Bauke Ylstra, Daphne de Jong, Yongsoo Kim
To understand the clinical significance of the tumor microenvironment (TME), it is essential to study the interactions between malignant and non-malignant cells in clinical specimens. Here, we established a computational framework for a multiplex ima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::485a918579920a60ac647e64c195bf89
https://doi.org/10.1101/2022.09.27.509403
https://doi.org/10.1101/2022.09.27.509403
Autor:
Paul Roepman, Danielle Cohen, Stephen P. Finn, Cathal O'Brien, Hein F.B.M. Sleddens, Kim Monkhorst, Karin Weijers, Guido M.J.M. Roemen, Isabelle C. Meijssen, Ernst-Jan M. Speel, Tom van Wezel, Winand N.M. Dinjens, Mirjam C. Boelens, H.J. Dubbink, Willemina R. R. Geurts-Giele, Jan H. von der Thüsen, Kris G. Samsom, Erik Thunnissen, Teodora Radonic
Publikováno v:
Radonic, T, Geurts-Giele, W R R, Samsom, K G, Roemen, G M J M, von der Thüsen, J H, Thunnissen, E, Meijssen, I C, Sleddens, H F B M, Dinjens, W N M, Boelens, M C, Weijers, K, Speel, E J M, Finn, S P, O'Brien, C, van Wezel, T, Cohen, D, Monkhorst, K, Roepman, P & Dubbink, H J 2021, ' RET Fluorescence In Situ Hybridization Analysis Is a Sensitive but Highly Unspecific Screening Method for RET Fusions in Lung Cancer ', Journal of Thoracic Oncology, vol. 16, no. 5, pp. 798-806 . https://doi.org/10.1016/j.jtho.2021.01.1619
Journal of Thoracic Oncology, 16(5), 798-806. Elsevier Science
Journal of Thoracic Oncology, 16(5), 798-806. International Association for the Study of Lung Cancer
Journal of Thoracic Oncology, 16(5), 798-806. Elsevier Science
Journal of Thoracic Oncology, 16(5), 798-806. International Association for the Study of Lung Cancer
Introduction: RET gene fusions are established oncogenic drivers in 1% of NSCLC. Accurate detection of advanced patients with RET fusions is essential to ensure optimal therapy choice. We investigated the performance of fluorescence in situ hybridiza
Autor:
Adriaan A. Lammertsma, Conny J. van der Laken, Yoony Y. J. Gent, Gerrit Jansen, Inge de Greeuw, Carla F. M. Molthoff, Durga M.S.H. Chandrupatla, Karin Weijers
Publikováno v:
BioMed Research International, Vol 2015 (2015)
BioMed Research International
BioMed Research International, 2015:509295. Hindawi Publishing Corporation
Chandrupatla, D M S H, Weijers, K, Gent, Y, de Greeuw, I, Lammertsma, A A, Jansen, G, van der Laken, C J & Molthoff, C F M 2015, ' Sustained Macrophage Infiltration upon Multiple Intra-Articular Injections: An Improved Rat Model of Rheumatoid Arthritis for PET Guided Therapy Evaluation ', BioMed Research International, vol. 2015, 509295 . https://doi.org/10.1155/2015/509295
BioMed Research International
BioMed Research International, 2015:509295. Hindawi Publishing Corporation
Chandrupatla, D M S H, Weijers, K, Gent, Y, de Greeuw, I, Lammertsma, A A, Jansen, G, van der Laken, C J & Molthoff, C F M 2015, ' Sustained Macrophage Infiltration upon Multiple Intra-Articular Injections: An Improved Rat Model of Rheumatoid Arthritis for PET Guided Therapy Evaluation ', BioMed Research International, vol. 2015, 509295 . https://doi.org/10.1155/2015/509295
To widen the therapeutic window for PET guided evaluation of novel anti-RA agents, modifications were made in a rat model of rheumatoid arthritis (RA). Arthritis was induced in the right knee of Wistar rats with repeated boosting to prolong articular
Autor:
Cornelis L. Verweij, G.J. Peters, Gerrit Jansen, Alexandre E. Voskuyl, Y. Gent, M. Blits, Karin Weijers, J.G.M. van der Heijden, Rik J. Scheper, W.F. Lems, Marjon Al, Carla F. M. Molthoff, B A C Dijkmans, Y. Aassaraf, J. van der Laken, Manohar Ratnam
Publikováno v:
Pteridines, Vol 24, Iss 1, Pp 21-26 (2013)
Jansen, G, Weijers, K, Blits, M, van der Heijden, J, Gent, Y, Al, M C M, van der Laken, J, Molthoff, C F M, Verweij, C L, Voskuyl, A E, Lems, W F, Scheper, R J, Peters, G J, Ratnam, M, Aassaraf, Y & Dijkmans, B A C 2013, ' Folates and antifolates in rheumatoid arthritis ', Pteridines, vol. 24, no. 1, pp. 21-26 . https://doi.org/10.1515/pterid-2013-0012
Pteridines, 24(1), 21-26. International Society of Pteridinology
Jansen, G, Weijers, K, Blits, M, van der Heijden, J, Gent, Y, Al, M C M, van der Laken, J, Molthoff, C F M, Verweij, C L, Voskuyl, A E, Lems, W F, Scheper, R J, Peters, G J, Ratnam, M, Aassaraf, Y & Dijkmans, B A C 2013, ' Folates and antifolates in rheumatoid arthritis ', Pteridines, vol. 24, no. 1, pp. 21-26 . https://doi.org/10.1515/pterid-2013-0012
Pteridines, 24(1), 21-26. International Society of Pteridinology
Almost all current standard treatment of care for patients with chronic inflammatory diseases such as rheumatoid arthritis (RA) includes the folate antagonist methotrexate (MTX). Despite the proven efficacy of MTX in RA treatment, it is anticipated t
Autor:
Marc C. Huisman, Conny J. van der Laken, Michael Kassiou, Yoony Y. J. Gent, Adriaan A. Lammertsma, Gerrit Jansen, Albert D. Windhorst, Karin Weijers, Carla F. M. Molthoff
Publikováno v:
Gent, Y, Weijers, K, Molthoff, C F M, Windhorst, A D, Huisman, M C, Kassiou, M, Jansen, G, Lammertsma, A A & van der Laken, C J 2014, ' Promising potential of new generation translocator protein tracers providing enhanced contrast of arthritis imaging by positron emission tomography in a rat model of arthritis ', Arthritis Research & Therapy, vol. 16, no. 2, R70 . https://doi.org/10.1186/ar4509
Arthritis Research & Therapy, 16(2):R70. BioMed Central
Arthritis Research & Therapy
Arthritis Research & Therapy, 16(2):R70. BioMed Central
Arthritis Research & Therapy
Introduction Early diagnosis of and subsequent monitoring of therapy for rheumatoid arthritis (RA) could benefit from detection of (sub)clinical synovitis. Imaging of (sub)clinical arthritis by targeting the translocator protein (TSPO) on activated m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2266bb7fec256d33b9aa0b329b913f2
https://research.vumc.nl/en/publications/77dc9d9b-a884-4a3f-81b2-93f7c6166689
https://research.vumc.nl/en/publications/77dc9d9b-a884-4a3f-81b2-93f7c6166689
Autor:
Albert D. Windhorst, Yoony Y. J. Gent, Desirée E.C. Smith, Carla F. M. Molthoff, Marc C. Huisman, Conny J. van der Laken, Sumith A. Kularatne, Adriaan A. Lammertsma, Gerrit Jansen, Karin Weijers, Philip S. Low
Publikováno v:
Department of Chemistry Faculty Publications
Arthritis Research & Therapy, 15(2):R37. BioMed Central
Gent, Y, Weijers, K, Molthoff, C F M, Windhorst, A D, Huisman, M C, Smith, D E C, Kularatne, S, Jansen, G, Low, P S, Lammertsma, A A & van der Laken, C J 2013, ' Evaluation of the novel folate receptor ligand [18F]fluoro-PEG-folate for macrophage targeting in a rat model of arthritis ', Arthritis Research & Therapy, vol. 15, no. 2, R37 . https://doi.org/10.1186/ar4191
Arthritis Research & Therapy
Arthritis Research & Therapy, 15(2):R37. BioMed Central
Gent, Y, Weijers, K, Molthoff, C F M, Windhorst, A D, Huisman, M C, Smith, D E C, Kularatne, S, Jansen, G, Low, P S, Lammertsma, A A & van der Laken, C J 2013, ' Evaluation of the novel folate receptor ligand [18F]fluoro-PEG-folate for macrophage targeting in a rat model of arthritis ', Arthritis Research & Therapy, vol. 15, no. 2, R37 . https://doi.org/10.1186/ar4191
Arthritis Research & Therapy
Introduction Detection of (subclinical) synovitis is relevant for both early diagnosis and monitoring of therapy of rheumatoid arthritis (RA). Previously, the potential of imaging (sub)clinical arthritis was demonstrated by targeting the translocator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4bb066dd46166dfae610f8d6f1f07b0
http://docs.lib.purdue.edu/cgi/viewcontent.cgi?article=1004&context=chempubs
http://docs.lib.purdue.edu/cgi/viewcontent.cgi?article=1004&context=chempubs
Autor:
Rik J. Scheper, Tanja D. de Gruijl, Karin Weijers, Klaas Hoekman, Cynthia M. Fehres, Hester van Cruijsen, Dinja Oosterhoff, Sinéad M. Lougheed, Giuseppe Giaccone, Robert A.A. van Boerdonk, Jelle J. Lindenberg
Publikováno v:
van Cruijsen, H, Oosterhoff, D, Lindenberg, J J, Lougheed, S M, Fehres, C M, Weijers, K, van Boerdonk, R A A, Giaccone, G, Scheper, R J, Hoekman, K & de Gruijl, T D 2011, ' Glioblastoma-induced inhibition of Langerhans cell differentiation from CD34(+) precursors is mediated by IL-6 but unaffected by JAK2/STAT3 inhibition. ', Immunotherapy, vol. 3, no. 9, pp. 1051-1061 . https://doi.org/10.2217/IMT.11.107
Immunotherapy, 3(9), 1051-1061. Future Medicine Ltd.
Immunotherapy, 3(9), 1051-1061. Future Medicine Ltd.
Aims: Langerhans cell (LC) infiltration has been observed in glioblastoma, but the glioblastoma microenvironment may be conditioned to resist antitumor immune responses. As little is known about how glioblastoma may affect dendritic cell differentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d63be9f152f85b98553277e230de1b
https://research.vumc.nl/en/publications/6385f69b-428c-4662-9ffc-0ff73d152d08
https://research.vumc.nl/en/publications/6385f69b-428c-4662-9ffc-0ff73d152d08
Autor:
Maya Huijberts, Johannes W. A. Smit, Ellen Kapiteijn, Johannes A. Romijn, Hendrieke C. Hoftijzer, Alberto M. Pereira, Hans Gelderblom, Marcel P. M. Stokkel, Karin Weijers, Hans Morreau, Karen A. Heemstra, Eleonora P M Corssmit
Publikováno v:
European journal of endocrinology / European Federation of Endocrine Societies, 161(6), 923-931. BioScientifica Ltd.
ObjectiveTreatment options for patients with radioactive iodine (RaI) refractory metastases of differentiated thyroid carcinoma (DTC) are limited. We studied the effects of the multitarget tyrosine kinase inhibitor sorafenib on the reinduction of RaI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a752f4f4ba70b6e52a8304dd2d39f9
https://pure.amc.nl/en/publications/beneficial-effects-of-sorafenib-on-tumor-progression-but-not-on-radioiodine-uptake-in-patients-with-differentiated-thyroid-carcinoma(c0227446-2851-4bc8-b73d-9e2459f6e690).html
https://pure.amc.nl/en/publications/beneficial-effects-of-sorafenib-on-tumor-progression-but-not-on-radioiodine-uptake-in-patients-with-differentiated-thyroid-carcinoma(c0227446-2851-4bc8-b73d-9e2459f6e690).html