Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Karin Valmsen"'
Autor:
Julia Smirnova, Julia Gavrilova, Andra Noormägi, Karin Valmsen, Hegne Pupart, Jinghui Luo, Vello Tõugu, Peep Palumaa
Publikováno v:
Molecules, Vol 27, Iss 10, p 3160 (2022)
The tight binding of Cu and Zn ions to superoxide dismutase 1 (SOD1) maintains the protein stability, associated with amyotrophic lateral sclerosis (ALS). Yet, the quantitative studies remain to be explored for the metal-binding affinity of wild-type
Externí odkaz:
https://doaj.org/article/ecf9baf0e71d4ec49be0493fac5d34c1
Autor:
Julia, Smirnova, Julia, Gavrilova, Andra, Noormägi, Karin, Valmsen, Hegne, Pupart, Jinghui, Luo, Vello, Tõugu, Peep, Palumaa
Publikováno v:
Molecules (Basel, Switzerland). 27(10)
The tight binding of Cu and Zn ions to superoxide dismutase 1 (SOD1) maintains the protein stability, associated with amyotrophic lateral sclerosis (ALS). Yet, the quantitative studies remain to be explored for the metal-binding affinity of wild-type
Autor:
Nigulas Samel, Külliki Varvas, Karin Valmsen, Helike Lõhelaid, Kristella Hansen, Reet Järving, Ivar Järving, Reet Kurg
Publikováno v:
Insect Biochemistry and Molecular Biology. 39:851-860
Prostaglandins, well-known lipid mediators in vertebrate animals, have also shown to play certain regulatory roles in insects and other arthropods acting on reproduction, immune system and ion transport. However, knowledge of their biosynthetic pathw
Autor:
Helike Lõhelaid, Ivar Järving, Karin Valmsen, Külliki Varvas, Reet Järving, Nigulas Samel, Malle Kreen
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1780:315-321
The conversion of fatty acid hydroperoxides to allene epoxides is catalysed by a cytochrome P450 in plants. In contrast, in the coral Plexaura homomalla, a catalase-related hemoprotein fused to the lipoxygenase (LOX) was found to function as an allen
Publikováno v:
The protein journal. 34(6)
Formation of amyloid-like fibrils by insulin was studied at different insulin concentrations, pH and temperatures. At low pH (pH 2.5) the insulin fibrillization occurred only at high (>10 μM) peptide concentrations, whereas at physiological pH value
Autor:
Nigulas Samel, Külliki Varvas, Claus Schneider, Alan R. Brash, William E. Boeglin, Ivar Järving, Karin Valmsen
Publikováno v:
European Journal of Biochemistry. 271:3533-3538
It has been known for 30 years that the gorgonian coral Plexaura homomalla contains either 15S- or 15R-configuration prostaglandins (PGs), depending on its location in the Caribbean. Recently we showed that the 15R-PGs in the R-variety of P. homomall
Autor:
William E. Boeglin, Alan R. Brash, Nigulas Samel, Karin Valmsen, Tõnis Pehk, Külliki Varvas, Ivar Järving, Reet Koljak
Publikováno v:
Proceedings of the National Academy of Sciences. 98:7700-7705
The highest concentrations of prostaglandins in nature are found in the Caribbean gorgonian Plexaura homomalla . Depending on its geographical location, this coral contains prostaglandins with typical mammalian stereochemistry (15 S -hydroxy) or the
Autor:
Nigulas Samel, Alan R. Brash, Külliki Varvas, Reet Koljak, Mart Ustav, Ivar Järving, William E. Boeglin, Reet Kurg, Karin Valmsen
Publikováno v:
Journal of Biological Chemistry. 276:7033-7040
In vertebrates, the synthesis of prostaglandin hormones is catalyzed by cyclooxygenase (COX)-1, a constitutively expressed enzyme with physiological functions, and COX-2, induced in inflammation and cancer. Prostaglandins have been detected in high c
Publikováno v:
Journal of Biological Chemistry. 274:9923-9929
Certain corals are rich natural sources of prostaglandins, the metabolic origin of which has remained undefined. By analogy with the lipoxygenase/allene oxide synthase pathway to jasmonic acid in plants, the presence of (8R)-lipoxygenase and allene o
Publikováno v:
Natural Product Letters. 2:111-114
A novel natural E-prostaglandin - 1a-1b-dihomo-2,3 didehydro-PGE2 (1) was isolated from ram seminal vesicles and its structure was elucidated by MS and NMR analysis.