Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Karin Ute Jooss"'
Autor:
Tanja D. de Gruijl, Kim M. van Pul, Ronald J.C.L.M. Vuylsteke, Petrousjka van den Tol, Alfons J.M. van den Eertwegh, Dafni Chondronasiou, Karin Ute Jooss, Jessica Notohardjo, Sinéad M. Lougheed, Anita G.M. Stam
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background The sentinel lymph node (SLN) is the first node to receive lymphatic drainage from the primary tumor and the site where naive T cells are first primed. As such it is of great importance in initiating an effective anti-tumor immune response
Autor:
Erica L. Bradshaw-Pierce, Peter J. O'Brien, Timothy P. Hickling, Paolo Vicini, Bernhard O. Palsson, Karin Ute Jooss, Michael G. Zager, Mary E. Spilker, Sirus Palsson
Publikováno v:
BMC Systems Biology
Palsson, Sirus; Hickling, Timothy P; Bradshaw-Pierce, Erica L; Zager, Michael; Jooss, Karin; O’Brien, Peter J; et al.(2013). The development of a fully-integrated immune response model (FIRM) simulator of the immune response through integration of multiple subset models. BMC Systems Biology, 7(1), 95. doi: http://dx.doi.org/10.1186/1752-0509-7-95. Retrieved from: http://www.escholarship.org/uc/item/15q2g4t1
Palsson, Sirus; Hickling, Timothy P; Bradshaw-Pierce, Erica L; Zager, Michael; Jooss, Karin; O’Brien, Peter J; et al.(2013). The development of a fully-integrated immune response model (FIRM) simulator of the immune response through integration of multiple subset models. BMC Systems Biology, 7(1), 95. doi: http://dx.doi.org/10.1186/1752-0509-7-95. Retrieved from: http://www.escholarship.org/uc/item/15q2g4t1
Background The complexity and multiscale nature of the mammalian immune response provides an excellent test bed for the potential of mathematical modeling and simulation to facilitate mechanistic understanding. Historically, mathematical models of th
Publikováno v:
Cancer Research. 76:LB-093
A successful cancer vaccine will activate the host immune system to induce a balanced T- and B-cell response to tumor-specific antigens that can lead to tumor regression. Effective cancer vaccines will need to overcome several challenges to accomplis
Autor:
Bas D. Koster, Dafni Chondronasiou, M. Petrousjka van den Tol, Alfons J.M. van den Eertwegh, Ronald J.C.L.M. Vuylsteke, Tanja D. de Gruijl, Kim M. van Pul, Sinéad M. Lougheed, Anita G.M. Stam, Karin Ute Jooss
Publikováno v:
Cancer Immunology Research. 4:B138-B138
While systemic immune checkpoint blockade is unsurpassed in the induction of clinically effective T cell immunity in advanced-stage melanoma patients, the risk of autoimmune-related side effects precludes its application in earlier stages. In a Phase
Autor:
A.J.M. van den Eertwegh, Anita G.M. Stam, Thomas Harding, N. Sacks, Sinéad M. Lougheed, Karin Ute Jooss, Saskia J. A. M. Santegoets, Winald R. Gerritsen, Kristen Hege, T.D. de Gruijl
Publikováno v:
Journal for Immunotherapy of Cancer
Meeting abstracts Immunotherapeutic approaches such as vaccination or immune checkpoint blockade have proven to be clinically active in prostate cancer, but only in fractions of treated patients; this calls for personalized application of these novel