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pro vyhledávání: '"Karin Storm van´s Gravesande"'
Autor:
Morten Grunnet, Kezhong Wu, Karin Storm van´s Gravesande, Katja E. Odening, Xuwen Peng, Jürgen Biermann, Christoph Bode, Anders Peter Larsen, Gideon Koren, Gerlind Franke, Manfred Zehender, Bo Hjorth Bentzen, Sophia Bahrke, Michael Brunner
Publikováno v:
Journal of Cardiovascular Pharmacology. 57:223-230
Transgenic rabbits expressing pore mutants of K(V)7.1 display a long QT syndrome 1 (LQT1) phenotype. Recently, NS1643 has been described to increase I(Kr).We hypothesized that NS1643 would shorten the action potential duration (APD(90)) in LQT1 rabbi