Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Karin Siegmund"'
Publikováno v:
Animals, Vol 14, Iss 13, p 2012 (2024)
International development organisations have improved billions of human lives in the Global South. However, in both their projects and advice to governments, most of these organisations neglect animal welfare. This blindspot matters. Poor welfare sta
Externí odkaz:
https://doaj.org/article/cf2b8ae34fb5422b9a82e7d730c2b6fb
Autor:
Etienne Galemou Yoga, Kristian Parey, Amina Djurabekova, Outi Haapanen, Karin Siegmund, Klaus Zwicker, Vivek Sharma, Volker Zickermann, Heike Angerer
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Respiratory complex I plays a key role in energy metabolism. Cryo-EM structure of a mutant accessory subunit LYRM6 from the yeast Yarrowia lipolytica and molecular dynamics simulations reveal conformational changes at the interface between LYRM6 and
Externí odkaz:
https://doaj.org/article/89bb52ee11ed43a19deeb0190964dfe0
Autor:
Alfredo Cabrera-Orefice, Etienne Galemou Yoga, Christophe Wirth, Karin Siegmund, Klaus Zwicker, Sergio Guerrero-Castillo, Volker Zickermann, Carola Hunte, Ulrich Brandt
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Proton pumping of mitochondrial complex I depends on the reduction of ubiquinone but the molecular mechanism of energy conversion is unclear. Here, the authors provide structural and biochemical evidence showing that movement of loop TMH1-2 in comple
Externí odkaz:
https://doaj.org/article/6efa54739f774befb5b738b28df7f4b2
Autor:
Kristian Parey, Ulrich Brandt, Hao Xie, Deryck J Mills, Karin Siegmund, Janet Vonck, Werner Kühlbrandt, Volker Zickermann
Publikováno v:
eLife, Vol 7 (2018)
Mitochondrial complex I has a key role in cellular energy metabolism, generating a major portion of the proton motive force that drives aerobic ATP synthesis. The hydrophilic arm of the L-shaped ~1 MDa membrane protein complex transfers electrons fro
Externí odkaz:
https://doaj.org/article/90f86f9129bc42aeb31d0ee493f2f270
Autor:
Kristian Parey, Volker Zickermann, Outi Haapanen, Werner Kühlbrandt, Janet Vonck, Ilka Wittig, Karin Siegmund, Deryck J. Mills, Vivek Sharma, Thomas Züllig, Simone Prinz, Harald Köfeler
Publikováno v:
Science Advances
Cryo-EM, yeast genetics, and simulations offer an integrated approach to assess structure, function, and assembly of complex I.
Respiratory complex I is a redox-driven proton pump, accounting for a large part of the electrochemical gradient that
Respiratory complex I is a redox-driven proton pump, accounting for a large part of the electrochemical gradient that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d81f03c73d61bba2406dd0a7b216026
https://doi.org/10.1126/sciadv.aax9484
https://doi.org/10.1126/sciadv.aax9484
Autor:
Outi Haapanen, Vivek Sharma, Volker Zickermann, Ilka Wittig, Etienne Galemou Yoga, Karin Siegmund
Respiratory complex I catalyses the reduction of ubiquinone (Q) from NADH coupled to proton pumping across the inner membrane of mitochondria. The electrical charging of the inner mitochondrial membrane drives the synthesis of ATP, which is used to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6772f594fd8c9f80e70becc80f5ddc54
http://hdl.handle.net/10138/304764
http://hdl.handle.net/10138/304764
Autor:
Deryck J. Mills, Hao Xie, Janet Vonck, Ulrich Brandt, Werner Kühlbrandt, Volker Zickermann, Kristian Parey, Karin Siegmund
Publikováno v:
eLife, Vol 7 (2018)
Elife, 7
eLife
Elife, 7
eLife
Mitochondrial complex I has a key role in cellular energy metabolism, generating a major portion of the proton motive force that drives aerobic ATP synthesis. The hydrophilic arm of the L-shaped ~1 MDa membrane protein complex transfers electrons fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1229d5421c070cd803a2a5502b43fa7
https://doi.org/10.7554/elife.39213
https://doi.org/10.7554/elife.39213
Autor:
Hamid R. Nasiri, Carola Hunte, Ulrich Brandt, Volker Zickermann, Karin Siegmund, Christophe Wirth, Harald Schwalbe
Publikováno v:
Science, 347, 6217, pp. 44-9
Science, 347, 44-9
Science, 347, 44-9
Energy conversion in complex 1 ATP, the energy source of the cell, is synthesized by a protein residing in the mitochondrial inner membrane. The synthesis is driven by a proton gradient generated by redox reactions that transfer electrons between a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a44508898beddb08d911c55a33536db3
https://hdl.handle.net/2066/153364
https://hdl.handle.net/2066/153364
Autor:
Kristian Parey, Karin Siegmund, Ulrich Brandt, Deryck J. Mills, Hao Xie, Volker Zickermann, Werner Kühlbrandt, Janet Vonck
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1859:e44
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70f80066b1f434db910d9def3a4a1141
https://doi.org/10.1016/j.bbabio.2018.09.133
https://doi.org/10.1016/j.bbabio.2018.09.133