Aqueous extracts of Desmodium adscendens (Fabaceae) possess in vitro antioxidant properties and protect hepatocytes from Carbone tetrachloride-induced injury and Hepatitis C Virus infection

Autor: Gisa Tiegs, Angèle N. Tchana, Karin Seron, Arnaud Fondjo Kouam, Paul F. Moundipa, Brice Fredy Nemg Simo, Pascal Dieudonne Djamen Chuisseu, Jonas Kouamouo, Jean Dubuisson, Nelly C.K. Younang, Boris R.G. Tietcheu

Publikováno v: Investigational Medicinal Chemistry and Pharmacology. 3:1-10

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::592bbc3d311a62f61e78322b2105d9fc
https://doi.org/10.31183/imcp.2020.00036

Functional carbon quantum dots as medical countermeasures to human coronavirus (HCoV)

Autor: Yen-Ting Chen, Jean Dubuisson, Emerson Giovanelli, Karin Seron, Rabah Boukherroub, Sandrine Belouzard, Alexandre Barras, Aleksandra Łoczechin, Sabine Szunerits, Nils Metzler-Nolte

Publikováno v: ACS Applied Materials & Interfaces
ACS Applied Materials & Interfaces, 2019, 11 (46), pp.42964-42974. ⟨10.1021/acsami.9b15032⟩
ACS Applied Materials & Interfaces, Washington, D.C. : American Chemical Society, 2019, 11 (46), pp.42964-42974. ⟨10.1021/acsami.9b15032⟩
ACS Applied Materials & Interfaces, Washington, D.C. : American Chemical Society, 2019, ⟨10.1021/acsami.9b15032⟩

Therapeutic options for the highly pathogenic human coronavirus (HCoV) infections are urgently needed. Anticoronavirus therapy is however challenging, as coronaviruses are biologically diverse and rapidly mutating. In this work, the antiviral activit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cda5877598db15e57475d0e2f5433dc3
https://hal.science/hal-02328361

Khaya grandifoliola C.DC: a potential source of active ingredients against hepatitis C virus in vitro

Autor: Yves Rouillé, Gaspard Deloison, Gisa Tiegs, Karin Seron, Pierre Mkounga, Priscille Brodin, Borris Rosnay Tietcheu Galani, Paul F. Moundipa, Gabriele Sass, Frederic Nico Njayou, Christine E. Loscher, Marie-Emmanuelle Sahuc

Publikováno v: Archives of Virology
Archives of Virology, 2016, 161 (5), pp.1169-1181. ⟨10.1007/s00705-016-2771-5⟩
Archives of Virology, Springer Verlag, 2016, 161 (5), pp.1169-1181. ⟨10.1007/s00705-016-2771-5⟩

International audience; In this study, we examined the antiviral properties of Khaya grandifoliola C.DC (Meliaceae) on the hepatitis C virus (HCV) life cycle in vitro and identified some of the chemical constituents contained in the fraction with the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e31916132db0e1f0d460495e613293
https://doi.org/10.1007/s00705-016-2771-5

Theaflavins, polyphenols of black tea, inhibit entry of hepatitis C virus

Autor: Yves Rouillé, Karin Seron, Jean Dubuisson, Alexandre Vandeputte, Tanoy Bandyopadhyay, Manoranjan Goswami, Priyabrata Chowdhury, Marie-Emmanuelle Sahuc, Priscille Brodin

The treatment of hepatitis C virus (HCV) infection by combination of direct acting antivirals (DAA), with different mode of action, has made substantial progress in the past few years. However, appearance of resistance and high cost of the therapy is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc92522695552744b7a788b7554fa2c
https://doi.org/10.1101/325126

An ecological approach to discover new bioactive extracts and products: the case of extremophile plants

Autor: Céline Rivière, Sevser Sahpaz, Yves Rouillé, Thierry Hennebelle, Christel Neut, Joëlle Quetin-Leclercq, Joanne Bero, Vincent Roumy, Riadh Ksouri, Ramla Sahli, Karin Seron, Abderrazak Smaoui, Claire Beaufay, Marie-Emmanuelle Sahuc

Publikováno v: Journal of Pharmacy and Pharmacology
Journal of Pharmacy and Pharmacology, Royal Pharmaceutical Society of Great Britain, 2017, 69 (8), pp.1041-1055. ⟨10.1111/jphp.12728⟩
Journal of Pharmacy and Pharmacology, 2017, 69 (8), pp.1041-1055. ⟨10.1111/jphp.12728⟩

Objectives Eight extremophile plants from Tunisia were screened to find natural products with benefits in human health. Methods These plants were collected in different areas in Tunisia. Their methanolic extracts were evaluated for their total phenol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd8f8c0d57e254d2b73d1c5e52d5cc04
https://hal.archives-ouvertes.fr/hal-02104464