Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Karin Schuster-Gossler"'
Autor:
Karin Schuster-Gossler, Karsten Boldt, Dorothee Bornhorst, Patricia Delany-Heiken, Marius Ueffing, Achim Gossler
Publikováno v:
BMC Research Notes, Vol 14, Iss 1, Pp 1-8 (2021)
Abstract Objective The mammalian Notch ligand DLL1 has essential functions during development. To visualise DLL1 in tissues, for sorting and enrichment of DLL1-expressing cells, and to efficiently purify DLL1 protein complexes we tagged DLL1 in mice
Externí odkaz:
https://doaj.org/article/594a58d95cca4b0a9f8c0a6997325e83
Autor:
Anja Beckers, Franziska Fuhl, Tim Ott, Karsten Boldt, Magdalena Maria Brislinger, Peter Walentek, Karin Schuster-Gossler, Jan Hegermann, Leonie Alten, Elisabeth Kremmer, Adina Przykopanski, Katrin Serth, Marius Ueffing, Martin Blum, Achim Gossler
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Cilia are protrusions of the cell surface and composed of hundreds of proteins many of which are evolutionary and functionally well conserved. In cells assembling motile cilia the expression of numerous ciliary components is under the contro
Externí odkaz:
https://doaj.org/article/4e99c332b9ed4435a10fd923ac28beb1
Autor:
Anja Beckers, Tim Ott, Karin Schuster-Gossler, Karsten Boldt, Leonie Alten, Marius Ueffing, Martin Blum, Achim Gossler
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract The transcription factor FOXJ1 is essential for the formation of motile cilia throughout the animal kingdom. Target genes therefore likely constitute an important part of the motile cilia program. Here, we report on the analysis of one of th
Externí odkaz:
https://doaj.org/article/136882a3519e42bc9a7e2b67c949699d
Autor:
Lena Tveriakhina, Karin Schuster-Gossler, Sanchez M Jarrett, Marie B Andrawes, Meike Rohrbach, Stephen C Blacklow, Achim Gossler
Publikováno v:
eLife, Vol 7 (2018)
DLL1 and DLL4 are Notch ligands with high structural similarity but context-dependent functional differences. Here, we analyze their functional divergence using cellular co-culture assays, biochemical studies, and in vivo experiments. DLL1 and DLL4 a
Externí odkaz:
https://doaj.org/article/3e44a1b2e4f44a3eb3307bd5a10ef345
Autor:
Tobias Bohnenpoll, Anna B Wittern, Tamrat M Mamo, Anna-Carina Weiss, Carsten Rudat, Marc-Jens Kleppa, Karin Schuster-Gossler, Irina Wojahn, Timo H-W Lüdtke, Mark-Oliver Trowe, Andreas Kispert
Publikováno v:
PLoS Genetics, Vol 13, Iss 8, p e1006951 (2017)
The differentiated cell types of the epithelial and mesenchymal tissue compartments of the mature ureter of the mouse arise in a precise temporal and spatial sequence from uncommitted precursor cells of the distal ureteric bud epithelium and its surr
Externí odkaz:
https://doaj.org/article/0b615fa6c4cc4a169b539894b62f7ea2
Autor:
Kristina Preuße, Lena Tveriakhina, Karin Schuster-Gossler, Cláudia Gaspar, Alexandra Isabel Rosa, Domingos Henrique, Achim Gossler, Michael Stauber
Publikováno v:
PLoS Genetics, Vol 11, Iss 6, p e1005328 (2015)
Notch signalling is a fundamental pathway that shapes the developing embryo and sustains adult tissues by direct communication between ligand and receptor molecules on adjacent cells. Among the ligands are two Delta paralogues, DLL1 and DLL4, that ar
Externí odkaz:
https://doaj.org/article/2ffcaf61c0d248b7a18b07854ece2d6f
Autor:
Katrin Serth, Karin Schuster-Gossler, Elisabeth Kremmer, Birte Hansen, Britta Marohn-Köhn, Achim Gossler
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123776 (2015)
Delta-like 3 (DLL3) is a member of the DSL family of Notch ligands in amniotes. In contrast to DLL1 and DLL4, the other Delta-like proteins in the mouse, DLL3 does not bind in trans to Notch and does not activate the receptor, but shows cis-interacti
Externí odkaz:
https://doaj.org/article/c446dd5f1da446f5af324aedb19bd5d0
Autor:
Manoj B Menon, Akihiro Sawada, Anuhar Chaturvedi, Pooja Mishra, Karin Schuster-Gossler, Melanie Galla, Axel Schambach, Achim Gossler, Reinhold Förster, Michael Heuser, Alexey Kotlyarov, Makoto Kinoshita, Matthias Gaestel
Publikováno v:
PLoS Genetics, Vol 10, Iss 8, p e1004558 (2014)
Cytokinesis terminates mitosis, resulting in separation of the two sister cells. Septins, a conserved family of GTP-binding cytoskeletal proteins, are an absolute requirement for cytokinesis in budding yeast. We demonstrate that septin-dependence of
Externí odkaz:
https://doaj.org/article/68172a3feed04f899b4f231c4b470dcf
Autor:
Carsten Rudat, Thomas Grieskamp, Christian Röhr, Rannar Airik, Christoph Wrede, Jan Hegermann, Bernhard G Herrmann, Karin Schuster-Gossler, Andreas Kispert
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112112 (2014)
The mesothelium, the lining of the coelomic cavities, and the urothelium, the inner lining of the urinary drainage system, are highly specialized epithelia that protect the underlying tissues from mechanical stress and seal them from the overlying fl
Externí odkaz:
https://doaj.org/article/1b83fd4de97948f4bc673f43b46c3fff
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e79050 (2013)
The Notch signaling pathway mediates the direct communication between adjacent cells and regulates multiple developmental processes. Interaction of the Notch receptor with its ligands induces the liberation of the intracellular portion of Notch (NICD
Externí odkaz:
https://doaj.org/article/5b4e2ccf3b5c44a6851a5c31f3ff5671