Výsledky vyhledávání - "Karin R Conradie"

Akademický článek

In black South Africans from rural and urban communities, the 4G/5G PAI-1 polymorphism influences PAI-1 activity, but not plasma clot lysis time.

Autor: Zelda de Lange, Dingeman C Rijken, Tiny Hoekstra, Karin R Conradie, Johann C Jerling, Marlien Pieters

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e83151 (2013)

Data on genetic and environmental factors influencing PAI-1 levels and their consequent effect on clot lysis in black African populations are limited. We identified polymorphisms in the promoter area of the PAI-1 gene and determined their influence o

Externí odkaz: https://doaj.org/article/60698d38e5fc425fb1cc22d24879b8e2

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C679X loss-of-function PCSK9 variant lowers fasting glucose levels in a black South African population: A longitudinal study

Autor: Tinashe Chikowore, Marike Cockeran, Tertia van Zyl, Karin R. Conradie

Publikováno v: Diabetes research and clinical practice. 144

Aims To determine the longitudinal association of the loss-of-function (LOF) PCSK9 variants (C679X and A443T), proxies of PCSK9 inhibitor drugs, with LDL-C, fasting glucose and glycated hemoglobin. Methods We conducted a five year, longitudinal study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264e0fd0e9b7724c36f4d6eff3a7c5d9
https://pubmed.ncbi.nlm.nih.gov/30227170

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Nutrient Patterns Associated with Fasting Glucose and Glycated Haemoglobin Levels in a Black South African Population

Autor: Karin R. Conradie, Pedro T. Pisa, Edelweiss Wentzel-Viljoen, Tertia van Zyl, Tinashe Chikowore, Edith J. M. Feskens

Publikováno v: Nutrients, 9(1):9
Nutrients
Nutrients, 9(1)
Nutrients, Vol 9, Iss 1, p 9 (2017)
Nutrients 9 (2017) 1
Nutrients; Volume 9; Issue 1; Pages: 9

Type 2 diabetes (T2D) burden is increasing globally. However, evidence regarding nutrient patterns associated with the biomarkers of T2D is limited. This study set out to determine the nutrient patterns associated with fasting glucose and glycated ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3b7f0689edd9ea246dc439f99cbb2a5
https://repository.publisso.de/resource/frl:6411607

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The dynamics of toxic Microcystis strains and microcystin production in two hypertrofic South African reservoirs

Autor: Karin R. Conradie, Sandra Barnard

Publikováno v: Harmful Algae. 20:1-10

The South African impoundments of Hartbeespoort and Roodeplaat experience excessive blooms of Microcystis species each year. Microcystins, produced primarily by strains of cyanobacteria belonging to the genera Microcystis, Anabaena and Planktothrix,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cb4fd591a20326afd1e7ef32205d17de
https://doi.org/10.1016/j.hal.2012.03.006

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Predictive utility of a genetic risk score of common variants associated with type 2 diabetes in a black South African population

Autor: Edith J. M. Feskens, Karin R. Conradie, Tinashe Chikowore, Tertia van Zyl

Publikováno v: Diabetes Research and Clinical Practice, 122, 1-8
Diabetes Research and Clinical Practice 122 (2016)

Aims To determine the predictive utility of polygenic risk scores of common variants associated with type 2 diabetes derived from the European and Asian ethnicities among a black South African population. Method Our study was a case-control study nes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259c3569c77a8a80fb4f315aff96f232
https://pubmed.ncbi.nlm.nih.gov/27744072

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Is HIV-1 infection associated with endothelial dysfunction in a population of African ancestry in South Africa?

Autor: J.M. Van Rooyen, Marlien Pieters, T. Hoekstra, Karin R. Conradie, Carla M.T. Fourie, Aletta E. Schutte

Publikováno v: Cardiovascular Journal of Africa

The chronic infection status suffered by HIV-infected individuals promotes chronic arterial inflammation and injury, which leads to dysfunction of the endothelium, atherosclerosis and thrombosis. Although HIV-1 subtype C is prevalent in South Africa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb13dee09088d335a04645886b19c3a
https://doi.org/10.5830/cvja-2010-056

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Common and rare single nucleotide polymorphisms in the LDLR gene are present in a black South African population and associate with low-density lipoprotein cholesterol levels

Autor: Johann C. Jerling, Karin R. Conradie, Tertia van Zyl, Edith J. M. Feskens

Publikováno v: Journal of Human Genetics, 59, 88-94
Journal of Human Genetics 59 (2014)

The LDL receptor has an essential role in regulating plasma LDL-C levels. Genetic variation in the LDLR gene can be associated with either lower or moderately raised plasma levels of LDL-C, or may cause familial hypercholesterolemia. The prevalence o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc81fccecb2aaaaa41970e4404ac272f
https://research.wur.nl/en/publications/common-and-rare-single-nucleotide-polymorphisms-in-the-ldlr-gene-

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In Black South Africans from Rural and Urban Communities, the 4G/5G PAI-1 Polymorphism Influences PAI-1 Activity, but Not Plasma Clot Lysis Time

Autor: Marlien Pieters, Zelda de Lange, Dingeman C. Rijken, Johann C. Jerling, Tiny Hoekstra, Karin R. Conradie

Publikováno v: PLoS One (print), 8(12). Public Library of Science
PLoS ONE, 8(12)
PLoS ONE
PLoS ONE, Vol 8, Iss 12, p e83151 (2013)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d408126772294c2db0d1fd33ce956f89
https://pure.eur.nl/en/publications/aaafb760-f381-43ba-b65d-3a456d8b1e1a

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Genetic diversity of vetiver isolates (Chrysopogon zizanioides/nigritanus) available in South Africa based on ITS, ndhF and rbcL sequencing analyses

Autor: Sandra Barnard, V. Diedericks, Karin R. Conradie

Publikováno v: South African Journal of Botany. :63-67

Vetiver grass (Chrysopogon zizanioides (L.) Roberty) is sterile and only regenerates vegetatively from clumps of the rootstock. Together with its vigorous and deep root system this makes it ideal for use in soil remediation and erosion control. In So

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::561f1c8481aae7a89993343515ec6cdc

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Akademický článek

Interactions between C-Reactive Protein Genotypes with Markers of Nutritional Status in Relation to Inflammation

Autor: Cornelie Nienaber-Rousseau, Bianca Swanepoel, Robin C. Dolman, Marlien Pieters, Karin R. Conradie, G. Wayne Towers

Publikováno v: Nutrients, Vol 6, Iss 11, Pp 5034-5050 (2014)

Inflammation, as indicated by C-reactive protein concentrations (CRP), is a risk factor for chronic diseases. Both genetic and environmental factors affect susceptibility to inflammation. As dietary interventions can influence inflammatory status, we

Externí odkaz: https://doaj.org/article/fe25bf4563d341b19f85f1376529a5ee

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