Zobrazeno 1 - 10
of 240
pro vyhledávání: '"Karin R, Sipido"'
Autor:
Dylan Vermoortele, Camilla Olianti, Matthew Amoni, Francesco Giardini, Stijn De Buck, Chandan K. Nagaraju, Rik Willems, H. Llewellyn Roderick, Karin R. Sipido, Leonardo Sacconi, Piet Claus
Publikováno v:
Communications Engineering, Vol 3, Iss 1, Pp 1-13 (2024)
Abstract Ventricular arrhythmias after myocardial infarction (MI) originate from discrete areas within the MI border zone (BZ), identified during functional electrophysiology tests. Accurate sampling of arrhythmogenic sites for ex-vivo study remains
Externí odkaz:
https://doaj.org/article/3a440345c44b4fcaa974c43e8964c968
Autor:
Luc Leybaert, Maarten A.J. De Smet, Alessio Lissoni, Rosalie Allewaert, H. Llewelyn Roderick, Geert Bultynck, Mario Delmar, Karin R. Sipido, Katja Witschas
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 6 (2023)
Connexins are crucial cardiac proteins that form hemichannels and gap junctions. Gap junctions are responsible for the propagation of electrical and chemical signals between myocardial cells and cells of the specialized conduction system in order to
Externí odkaz:
https://doaj.org/article/c31bdf27fc3543e5b9392e8b80979d2e
Autor:
Guillaume Gilbert, Chandan Kadur Nagaraju, Robin Duelen, Matthew Amoni, Pierre Bobin, Thomas Eschenhagen, H. Llewelyn Roderick, Maurilio Sampaolesi, Karin R. Sipido
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Human induced pluripotent stem cells derived cardiomyocytes (hiPSC-CM) are increasingly used to study genetic diseases on a human background. However, the lack of a fully mature adult cardiomyocyte phenotype of hiPSC-CM may be limiting the scope of t
Externí odkaz:
https://doaj.org/article/b35c150cb7c84d46b27ae8cd2dd0d249
Autor:
Chandan K. Nagaraju, Eef Dries, Guillaume Gilbert, Mouna Abdesselem, Nan Wang, Matthew Amoni, Ronald B. Driesen, Karin R. Sipido
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract After myocardial infarction, resident fibroblasts (Fb) differentiate towards myofibroblasts (MyoFb), generating the scar tissue and the interstitial fibrosis seen in the adjacent myocardium. Fb and MyoFb have the potential to interact with c
Externí odkaz:
https://doaj.org/article/d7d7434f9c4241de92ebb91f7526f189
Autor:
Emma L. Robinson, Faye M. Drawnel, Saher Mehdi, Caroline R. Archer, Wei Liu, Hanneke Okkenhaug, Kanar Alkass, Jan Magnus Aronsen, Chandan K. Nagaraju, Ivar Sjaastad, Karin R. Sipido, Olaf Bergmann, J. Simon C. Arthur, Xin Wang, H. Llewelyn Roderick
Publikováno v:
Cells, Vol 11, Iss 4, p 604 (2022)
Heart failure is a leading cause of death that develops subsequent to deleterious hypertrophic cardiac remodelling. MAPK pathways play a key role in coordinating the induction of gene expression during hypertrophy. Induction of the immediate early ge
Externí odkaz:
https://doaj.org/article/a244854a2c694e5daf4f6e2ef48d4de1
Autor:
Matthew Amoni, Eef Dries, Sebastian Ingelaere, Dylan Vermoortele, H. Llewelyn Roderick, Piet Claus, Rik Willems, Karin R. Sipido
Publikováno v:
Cells, Vol 10, Iss 10, p 2629 (2021)
Ischemic heart disease is the most common cause of lethal ventricular arrhythmias and sudden cardiac death (SCD). In patients who are at high risk after myocardial infarction, implantable cardioverter defibrillators are the most effective treatment t
Externí odkaz:
https://doaj.org/article/0f097316d9bc420dac4b8642e6727c44
Autor:
Sophie Deckx, Daniel M Johnson, Marieke Rienks, Paolo Carai, Elza Van Deel, Jolanda Van der Velden, Karin R Sipido, Stephane Heymans, Anna-Pia Papageorgiou
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0209534 (2019)
Secreted protein acidic and rich in cysteine (SPARC) is a non-structural extracellular matrix protein that regulates interactions between the matrix and neighboring cells. In the cardiovascular system, it is expressed by cardiac fibroblasts, endothel
Externí odkaz:
https://doaj.org/article/1d9d07c7f7c14ca887495945e5664644
Autor:
Dylan Vermoortele, Matthew Amoni, Sebastian Ingelaere, Karin R. Sipido, Rik Willems, Piet Claus
Publikováno v:
JACC: Clinical Electrophysiology.
Autor:
Tim De Coster, Piet Claus, Gunnar Seemann, Rik Willems, Karin R. Sipido, Alexander V. Panfilov
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
The onset of cardiac arrhythmias depends on the electrophysiological and structural properties of cardiac tissue. Electrophysiological remodeling of myocytes due to the presence of adipocytes constitutes a possibly important pathway in the pathogenes
Externí odkaz:
https://doaj.org/article/6c49514d010b4af682b0cd8cda247b83
Autor:
Karin R. Sipido, Rik Willems, Piet Claus, Kanigula Mubagwa, Roisin Kelly-Laubscher, Arieh A. Katz, Asfree Gwanyanya
Publikováno v:
Heart Rhythm. 20:793-794