Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Karin P. Potoka"'
Autor:
William E Truog, Huayan Zhang, Beth Haberman, Sara Mūnoz-Blanco, Joanne Lagatta, Erica Wymore, Leif D. Nelin, Nicolas F M Porta, Robert DiGeronimo, Karna Murthy, Joana Machry, Rashmin C. Savani, Sushmita Yallapragada, Shilpa Vyas-Read, Karin P Potoka, Girija Natarajan
Publikováno v:
Journal of Perinatology
BACKGROUND The decision to pursue chronic mechanical ventilation involves a complex mix of clinical and social considerations. Understanding the medical indications to pursue tracheostomy would reduce the ambiguity for both providers and families and
Autor:
Johannes-Peter Stasch, Tim Bachman, Eva-Maria Becker-Pelster, Matthias Beat Wittwer, Grant C. Bullock, Scott A. Hahn, Hubert Truebel, Mark T. Gladwin, Grace M Mallampalli, Katherine C. Wood, Valerie Schrott, Jeffrey J. Baust, Ilka Mathar, Karin P. Potoka, Jan Stampfuss, Peter Sandner, Adam C. Straub, Ana L. Mora, Marta Bueno, Bin Sun, David O. Osei-Hwedieh, Rebecca Vanderpool
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 58:636-647
Sickle cell disease (SCD) is associated with intravascular hemolysis and oxidative inhibition of nitric oxide (NO) signaling. BAY 54-6544 is a small-molecule activator of oxidized soluble guanylate cyclase (sGC), which, unlike endogenous NO and the s
Autor:
William E. Truog, Robert DiGeronimo, William A. Engle, Joanne Lagatta, Michael A. Padula, Leif D. Nelin, Karna Murthy, Shilpa Vyas-Read, Rashmin C. Savani, Isabella Zaniletti, Erica Wymore, Erik B. Hysinger, Sushmita Yallapragada, Girija Natarajan, Theresa R. Grover, Karin P Potoka, Huayan Zhang, J. Wells Logan, Nicolas F M Porta
Publikováno v:
Journal of Perinatology
Objective To determine the relationship between interventricular septal position (SP) and right ventricular systolic pressure (RVSP) and mortality in infants with severe BPD (sBPD). Study design Infants with sBPD in the Children’s Hospitals Neonata
Autor:
Mark T. Gladwin, Natasha M. Rogers, Lynda Little-Ihrig, Daniel N. Meijles, Evan DeVallance, George Miles, Mingyi Yao, Mark A. Ross, Jeffrey J. Baust, Karin P. Potoka, Patrick J. Pagano, Claudette M. St. Croix, Heather E. Knupp, Jeffrey S. Isenberg, Enrico M. Novelli
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Pulmonary hypertension (PH) is a leading cause of death in sickle cell disease (SCD) patients. Hemolysis and oxidative stress contribute to SCD-associated PH. We have reported that the protein thrombospondin-1 (TSP1) is elevated in the plasma of pati
Autor:
Mark T. Gladwin, Karin P. Potoka
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 308:L314-L324
Sickle cell disease (SCD) is an autosomal recessive disorder in the gene encoding the β-chain of hemoglobin. Deoxygenation causes the mutant hemoglobin S to polymerize, resulting in rigid, adherent red blood cells that are entrapped in the microcirc
Autor:
Rashmin C. Savani, Isabella Zaniletti, Shilpa Vyas-Read, Sushmita Yallapragada, William E Truog, Huayan Zhang, Theresa R. Grover, Erik B. Hysinger, William A. Engle, Michael A. Padula, Nicolas F M Porta, Girija Natarajan, Erica Wymore, Steven M. Kawut, Robert DiGeronimo, Karna Murthy, Joanne Lagatta, Leif D. Nelin, Karin P Potoka
Publikováno v:
The Journal of Pediatrics. 203:218-224.e3
Objectives To assess the effect of pulmonary hypertension on neonatal intensive care unit mortality and hospital readmission through 1 year of corrected age in a large multicenter cohort of infants with severe bronchopulmonary dysplasia. Study design
Publikováno v:
Blood. 132:1060-1060
Sickle cell anemia results from a point mutation in both alleles of the β-globin gene. This homozygous mutation ultimately leads to a structural alteration of the hemoglobin protein that promotes polymerization of the mutant sickle hemoglobin tetram
Autor:
Mingyi Yao, Jeffrey S. Isenberg, Mark A. Ross, Heather E. Knupp, Karin P. Potoka, Patrick J. Pagano, Claudette M. St. Croix, Daniel N. Meijles, Enrico M. Novelli, George Miles, Jeffrey J. Baust, Lynda Ihrig, Hunter C. Champion, Mark T. Gladwin, Xiaojun Huang, Natasha M. Rogers
Publikováno v:
Web of Science
Pulmonary hypertension (PH) is a chronic pulmonary complication of sickle cell disease (SCD) and a leading cause of death in adults. The exact molecular causes of SCD-associated PH are unknown although pathologic hemolysis related to chronic nitric o