Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Karin Nienhaus"'
Autor:
Martin Štefl, Masanari Takamiya, Volker Middel, Miyase Tekpınar, Karin Nienhaus, Tanja Beil, Sepand Rastegar, Uwe Strähle, Gerd Ulrich Nienhaus
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108849- (2024)
Summary: Repair of lesions in the plasma membrane is key to sustaining cellular homeostasis. Cells maintain cytoplasmic as well as membrane-bound stores of repair proteins that can rapidly precipitate at the site of membrane lesions. However, little
Externí odkaz:
https://doaj.org/article/b4511a54e95f4dbc9f67e39a510c4315
Autor:
Nane C. Kuznik, Valeria Solozobova, Irene I. Lee, Nicole Jung, Linxiao Yang, Karin Nienhaus, Emmanuel A. Ntim, Jaice T. Rottenberg, Claudia Muhle-Goll, Amrish Rajendra Kumar, Ravindra Peravali, Simone Gräßle, Victor Gourain, Célia Deville, Laura Cato, Antje Neeb, Marco Dilger, Christina A. Cramer von Clausbruch, Carsten Weiss, Bruno Kieffer, G. Ulrich Nienhaus, Myles Brown, Stefan Bräse, Andrew C.B. Cato
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104175- (2022)
Summary: BAG1 is a family of polypeptides with a conserved C-terminal BAG domain that functions as a nucleotide exchange factor for the molecular chaperone HSP70. BAG1 proteins also control several signaling processes including proteostasis, apoptosi
Externí odkaz:
https://doaj.org/article/ef7d174a265a47ad8c77177cd0835a85
Autor:
Antonia Franziska Eckert, Peng Gao, Janine Wesslowski, Xianxian Wang, Jasmijn Rath, Karin Nienhaus, Gary Davidson, Gerd Ulrich Nienhaus
Publikováno v:
eLife, Vol 9 (2020)
Development and homeostasis of multicellular organisms is largely controlled by complex cell-cell signaling networks that rely on specific binding of secreted ligands to cell surface receptors. The Wnt signaling network, as an example, involves multi
Externí odkaz:
https://doaj.org/article/eda06825faa94ae3b299d7bc550f4be1
Autor:
Karin Nienhaus, G. Ulrich Nienhaus
Publikováno v:
Frontiers in Molecular Biosciences, Vol 4 (2018)
The human heme enzymes tryptophan 2,3-dioxygenase (hTDO) and indoleamine 2,3 dioxygenase (hIDO) catalyze the initial step in L-tryptophan (L-Trp) catabolism, the insertion of dioxygen into L-Trp. Overexpression of these enzymes causes depletion of L-
Externí odkaz:
https://doaj.org/article/26a0bcd950074c4e8de5d1c424a54f2a
Autor:
Li Shang, Karin Nienhaus, Xiue Jiang, Linxiao Yang, Katharina Landfester, Volker Mailänder, Thomas Simmet, G. Ulrich Nienhaus
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 5, Iss 1, Pp 2388-2397 (2014)
Engineered nanomaterials are known to enter human cells, often via active endocytosis. Mechanistic details of the interactions between nanoparticles (NPs) with cells are still not well enough understood. NP size is a key parameter that controls the e
Externí odkaz:
https://doaj.org/article/d030bfc0ba5b4fa0bb0703f375a68dc1
Autor:
Pauline Maffre, Stefan Brandholt, Karin Nienhaus, Li Shang, Wolfgang J. Parak, G. Ulrich Nienhaus
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 5, Iss 1, Pp 2036-2047 (2014)
By using fluorescence correlation spectroscopy (FCS), we have studied the adsorption of human serum albumin (HSA) onto Fe–Pt nanoparticles (NPs, 6 nm radius), CdSe/ZnS quantum dots (QDs, 5 nm radius) and Au and Ag nanoclusters (1–4 nm radius), wh
Externí odkaz:
https://doaj.org/article/c25676f8ae9044b082e673eb4fd23c18
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 2, Iss 1, Pp 374-383 (2011)
Using dual-focus fluorescence correlation spectroscopy, we have analyzed the adsorption of three human blood serum proteins, namely serum albumin, apolipoprotein A-I and apolipoprotein E4, onto polymer-coated, fluorescently labeled FePt nanoparticles
Externí odkaz:
https://doaj.org/article/29f1f9673f054139aa172b40340f912f
Publikováno v:
F1000Research, Vol 3 (2014)
Inducible nitric oxide synthase (iNOS) is a homodimeric heme enzyme that catalyzes the formation of nitric oxide (NO) from dioxygen and L-arginine (L-Arg) in a two-step process. The produced NO can either diffuse out of the heme pocket into the surro
Externí odkaz:
https://doaj.org/article/19e9d6f41c57448bad113598a94c5918
Autor:
Simone Kredel, Franz Oswald, Karin Nienhaus, Karen Deuschle, Carlheinz Röcker, Michael Wolff, Ralf Heilker, G Ulrich Nienhaus, Jörg Wiedenmann
Publikováno v:
PLoS ONE, Vol 4, Iss 2, p e4391 (2009)
A monomeric variant of the red fluorescent protein eqFP611, mRuby, is described. With excitation and emission maxima at 558 nm and 605 nm, respectively, and a large Stokes shift of 47 nm, mRuby appears particularly useful for imaging applications. Th
Externí odkaz:
https://doaj.org/article/a78ff627c6f9449e8a1031c882d8b63a
Publikováno v:
Chinese Journal of Chemistry, 40 (22), 2685-2693
We have studied interactions between positively charged MUTAB-stabilized quantum dots (QDs) and model proteins, serum and live cells using fluorescence correlation spectroscopy (FCS), dynamic light scattering (DLS), time-resolved photoluminescence (P