Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Karin Mitosch"'
Autor:
Karin Mitosch, Martin Beyß, Prasad Phapale, Bernhard Drotleff, Katharina Nöh, Theodore Alexandrov, Kiran R Patil, Athanasios Typas
Publikováno v:
PLoS Biology, Vol 21, Iss 8, p e3002198 (2023)
Pathogenic bacteria proliferating inside mammalian host cells need to rapidly adapt to the intracellular environment. How they achieve this and scavenge essential nutrients from the host has been an open question due to the difficulties in distinguis
Externí odkaz:
https://doaj.org/article/eb9d89e1b0b643e18e61f852a3fec525
Autor:
S Andreas Angermayr, Tin Yau Pang, Guillaume Chevereau, Karin Mitosch, Martin J Lercher, Tobias Bollenbach
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 9, Pp n/a-n/a (2022)
Abstract Dose–response relationships are a general concept for quantitatively describing biological systems across multiple scales, from the molecular to the whole‐cell level. A clinically relevant example is the bacterial growth response to anti
Externí odkaz:
https://doaj.org/article/38e5047417c44c76b6e1a35a6ea93e6e
Autor:
Joel Selkrig, Megan Stanifer, André Mateus, Karin Mitosch, Inigo Barrio‐Hernandez, Mandy Rettel, Heeyoung Kim, Carlos G P Voogdt, Philipp Walch, Carmon Kee, Nils Kurzawa, Frank Stein, Clément Potel, Anna Jarzab, Bernhard Kuster, Ralf Bartenschlager, Steeve Boulant, Pedro Beltrao, Athanasios Typas, Mikhail M Savitski
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 2, Pp n/a-n/a (2021)
Abstract The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a global threat to human health and has compromised economic stability. In addition to the development of an effective vaccine, it is imperative to understand how SARS
Externí odkaz:
https://doaj.org/article/afece9f0c9684154826067b58f6e27a7
Publikováno v:
Molecular Systems Biology, Vol 15, Iss 2, Pp n/a-n/a (2019)
Abstract Sudden stress often triggers diverse, temporally structured gene expression responses in microbes, but it is largely unknown how variable in time such responses are and if genes respond in the same temporal order in every single cell. Here,
Externí odkaz:
https://doaj.org/article/defd8ab26a4c4e198e0955c4ea5c4d39
Autor:
Jacob Bobonis, Karin Mitosch, André Mateus, Nicolai Karcher, George Kritikos, Joel Selkrig, Matylda Zietek, Vivian Monzon, Birgit Pfalz, Sarela Garcia-Santamarina, Marco Galardini, Anna Sueki, Callie Kobayashi, Frank Stein, Alex Bateman, Georg Zeller, Mikhail M. Savitski, Johanna R. Elfenbein, Helene L. Andrews-Polymenis, Athanasios Typas
Publikováno v:
Nature. 609:144-150
Autor:
Elisabetta Cacace, Vladislav Kim, Michael Knopp, Manuela Tietgen, Amber Brauer-Nikonow, Kemal Inecik, André Mateus, Alessio Milanese, Marita Torrissen Mårli, Karin Mitosch, Joel Selkrig, Ana Rita Brochado, Oscar P. Kuipers, Morten Kjos, Georg Zeller, Mikhail M. Savitski, Stephan Göttig, Wolfgang Huber, Athanasios Typas
Drug combinations present a powerful strategy to tackle antimicrobial resistance, but have not been systematically tested in many bacterial species. Here, we used an automated high-throughput setup to profile ∼ 8000 combinations between 65 antibact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69940cd54719419b5b92db68ebc2407d
https://doi.org/10.1101/2022.12.23.521747
https://doi.org/10.1101/2022.12.23.521747
Publikováno v:
BIOspektrum. 27:355-357
VAAM-Forschungspreis 2021Bacterial retrons are operons containing reverse transcriptases. Despite three decades of research, their physiological role remained mysterious. Recently, retrons have been uncovered as a widespread novel class of antiphage
Autor:
Max Frank, Sibylle C. Vonesch, Vladimir Benes, Kim Remans, Julia Kornienko, Ferris Jung, Danila Bredikhin, Juergen Zimmermann, Hans-Georg Kraeusslich, Rozemarijn Kleinendorst, Arnaud R Krebs, Axel Hamprecht, Elisabetta Cacace, Julia Flock, Mireia Osuna-Lopez, Laura Villacorta, Karin Mitosch, Lars M. Steinmetz, Stephan Goettig, Nikolay Dobrev, Athanasios Typas, Michael Knop
McQ is a SARS-CoV-2 quantification assay that couples early-stage barcoding with high-throughput sequencing to enable multiplexed processing of thousands of samples. McQ is based on homemade enzymes to enable low-cost testing of large sample pools, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a17caa490b5364c13b862b79218eb5e4
https://doi.org/10.1101/2020.12.02.20242628
https://doi.org/10.1101/2020.12.02.20242628
Autor:
Megan L. Stanifer, Joel Selkrig, Anna Jarzab, Philipp Walch, Bernhard Kuster, Heeyoung Kim, Pedro Beltrao, Mikhail M. Savitski, Inigo Barrio-Hernandez, Frank Stein, Mandy Rettel, Ralf Bartenschlager, Athanasios Typas, Karin Mitosch, André Mateus, Carmon Kee, Nils Kurzawa, Clement M. Potel, Carlos G P Voogdt, Steeve Boulant
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 2, Pp n/a-n/a (2021)
Research Square
Molecular systems biology, 17(2):e10188
Molecular Systems Biology
Molecular systems biology 17(2), e10188 (2021). doi:10.15252/msb.202010188
Molecular Systems Biology, 17 (2)
Research Square
Molecular systems biology, 17(2):e10188
Molecular Systems Biology
Molecular systems biology 17(2), e10188 (2021). doi:10.15252/msb.202010188
Molecular Systems Biology, 17 (2)
The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a global threat to human health and has compromised economic stability. In addition to the development of an effective vaccine, it is imperative to understand how SARS‐CoV‐2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ca0d52e28e9055e1fab6128cacaac9
https://doi.org/10.21203/rs.3.rs-105193/v1
https://doi.org/10.21203/rs.3.rs-105193/v1
Autor:
Jacob Bobonis, André Mateus, Mikhail M. Savitski, George Kritikos, Elfenbein, Athanasios Typas, Karin Mitosch, Helene Andrews-Polymenis
Bacteria carry dozens of Toxin/Antitoxin systems (TAs) in their chromosomes. Upon growth, the antitoxin is co-expressed and neutralizes the toxin. TAs can be activated and inhibit growth, but when and how this occurs has largely remained enigmatic, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32877382a3ba2cbb52ab39c6110dbd5b
https://doi.org/10.1101/2020.06.22.160242
https://doi.org/10.1101/2020.06.22.160242