Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Karin M.L. Gaensler"'
Autor:
Li-Wen Huang, Ying Sheng, Charalambos Andreadis, Aaron C. Logan, Gabriel N. Mannis, Catherine C. Smith, Karin M.L. Gaensler, Thomas G. Martin, Lloyd E. Damon, Chiung-Yu Huang, Rebecca L. Olin
Publikováno v:
Transplantation and cellular therapy, vol 28, iss 6
As allogeneic hematopoietic cell transplantation (alloHCT) is increasingly offered to older adults, geriatric assessment (GA) has been identified as a useful tool for predicting outcomes, particularly functional status. However, very few studies have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40baf3ecbaa984ca3a114943e60a30b3
https://escholarship.org/uc/item/1fd8x22h
https://escholarship.org/uc/item/1fd8x22h
Autor:
Karin M.L. Gaensler, Charalambos Andreadis, Ravi K. Patel, Michael Flanders, Chun Jimmie Ye, Arjun A. Rao, Rebecca L. Olin, Vivian Weinberg, Bradley W. Blaser, Tommy Jiang, Frank McCormick, David P. Carbone, Pamela N. Munster, Aaron C Logan, Victoria E. Wang, Gregory K. Behbehani, Lloyd E. Damon, Blythe Durbin-Johnson, Matthew L. Settles, Peter H. Sayre, Gabriel N. Mannis, Thomas G. Martin, Gabriela K. Fragiadakis, Emma McMahon
Publikováno v:
Blood Cancer Discov
Blood cancer discovery, vol 2, iss 5
Blood cancer discovery, vol 2, iss 5
Acute myeloid leukemia (AML) patients refractory to induction therapy or relapsed within 1 year have poor outcomes. Autocrine production of hepatocyte growth factor by myeloid blasts drives leukemogenesis in preclinical models. A phase Ib trial evalu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af9f5ea3caf0d25186aa2f35c09bf3b
https://pubmed.ncbi.nlm.nih.gov/34514432
https://pubmed.ncbi.nlm.nih.gov/34514432
Autor:
Charalambos Andreadis, Gabriel N. Mannis, Chiung Yu Huang, Thomas G. Martin, Lloyd E. Damon, Aaron C Logan, Catherine C. Smith, Karin M.L. Gaensler, Rebecca L. Olin, Li-Wen Huang, Michael A. Steinman, Ying Sheng
Publikováno v:
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, vol 26, iss 1
Biol Blood Marrow Transplant
Biol Blood Marrow Transplant
Allogeneic hematopoietic cell transplantation (alloHCT) has been increasingly offered to older adults with hematologic malignancies. However, optimal methods to determine fitness for alloHCT have yet to be defined. We evaluated the ability of a compr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8437a715e14a4c5dae9980637aab5071
https://escholarship.org/uc/item/57p569hf
https://escholarship.org/uc/item/57p569hf
Autor:
Karin M.L. Gaensler, Yimin Shi, Cristina Bergamaschi, George N. Pavlakis, Farzin Farzaneh, Jeffrey P. Fung, Charles E. Ayemoba, Lillia Dincheva-Vogel
Publikováno v:
Blood Advances. 2:3177-3192
Engineered autologous acute myeloid leukemia (AML) cells present multiple leukemia-associated and patient-specific antigens and as such hold promise as immunotherapeutic vaccines. However, prior vaccines have not reliably induced effective antileukem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c86d0f8c0ee7e49fef3952f1a2dc3444
https://doi.org/10.1182/bloodadvances.2018019026
https://doi.org/10.1182/bloodadvances.2018019026
Autor:
Lori J. Maness, Paul J. Shami, Peter Westervelt, H. Joachim Deeg, Virginia M. Klimek, Guillermo Garcia-Manero, Amer M. Zeidan, Hetty E. Carraway, Daniel A. Pollyea, Rami S. Komrokji, John M. Bennett, Karin M.L. Gaensler, Amir T. Fathi, Olga Frankfurt, Peter L. Greenberg, Carlos M. de Castro, Aref Al-Kali, Margaret R. O'Donnell, Lisa Kujawski, Alison Walker, Richard Stone, Robert A. Johnson, Ruth Horsfall, Amy E. DeZern, David R. Head, Elizabeth A. Griffiths, Mark B. Juckett, Rafael Bejar, Dorothy A. Shead, Brady L. Stein, Stefan K. Barta, Courtney Smith
Publikováno v:
Journal of the National Comprehensive Cancer Network. 15:60-87
The myelodysplastic syndromes (MDS) comprise a heterogenous group of myeloid disorders with a highly variable disease course. Diagnostic criteria to better stratify patients with MDS continue to evolve, based on morphology, cytogenetics, and the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca174dfbe5200b5801e70bf1d0111d61
https://doi.org/10.6004/jnccn.2017.0007
https://doi.org/10.6004/jnccn.2017.0007
Autor:
Charalambos Andreadis, Scott Thomas, McNancy Kang, Aaron C Logan, Matthew J. Wieduwilt, Nela Pawlowska, Karin M.L. Gaensler, Pamela N. Munster, Thomas Martin, Wanda Boyer, Peter H. Sayre, Lloyd E. Damon, Rebecca L. Olin, Kirsten Anderson
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 25(16)
Purpose: The histone deacetylase (HDAC) inhibitor panobinostat potentiates anthracycline and cytarabine cytotoxicity in acute myeloid leukemia (AML) cells. We hypothesized that panobinostat prior to and during induction chemotherapy would be tolerabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ef01328d3defea424a5b9ab6bfa6dc
https://pubmed.ncbi.nlm.nih.gov/31152020
https://pubmed.ncbi.nlm.nih.gov/31152020
Autor:
Catherine C. Smith, Jeffrey L. Wolf, Lawrence D. Kaplan, Charalambos Andreadis, Michael Flanders, Peter H. Sayre, Gabriel N. Mannis, Thomas G. Martin, Weiyun Z. Ai, Rebecca L. Olin, Lloyd E. Damon, Aaron C Logan, Karin M.L. Gaensler
Publikováno v:
Leukemia & Lymphoma. 57:1560-1566
In 2014, autologous hematopoietic cell transplant (autoHCT) was removed from the National Comprehensive Cancer Network guidelines as a recommended treatment for patients with intermediate-risk AML in first complete remission (CR1). We reviewed the ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efddfed638f1faaf1090be1cca40b48d
https://doi.org/10.3109/10428194.2015.1088646
https://doi.org/10.3109/10428194.2015.1088646
Autor:
Lianne S. Gensler, Haley B. Naik, Tiffany C. Scharschmidt, Timothy H. Schmidt, Lindy P. Fox, Lina Saeed, Karin M.L. Gaensler, Kanade Shinkai, Michael Rosenblum, Andrew J. Gross
Publikováno v:
JAAD case reports, vol 4, iss 1
JAAD Case Reports, Vol 4, Iss 1, Pp 81-83 (2018)
JAAD Case Reports
Saeed, L; Schmidt, TH; Gensler, LS; Gross, AJ; Fox, LP; Scharschmidt, TC; et al.(2018). Successful treatment of mucous membrane pemphigoid with bortezomib.. JAAD case reports, 4(1), 81-83. doi: 10.1016/j.jdcr.2017.08.005. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/7v07r0st
JAAD Case Reports, Vol 4, Iss 1, Pp 81-83 (2018)
JAAD Case Reports
Saeed, L; Schmidt, TH; Gensler, LS; Gross, AJ; Fox, LP; Scharschmidt, TC; et al.(2018). Successful treatment of mucous membrane pemphigoid with bortezomib.. JAAD case reports, 4(1), 81-83. doi: 10.1016/j.jdcr.2017.08.005. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/7v07r0st
Mucous membrane pemphigoid (MMP) is a rare, autoantibody-mediated disease characterized by mucocutaneous blistering including oral, ocular, laryngeal, and skin involvement. Treating MMP is challenging, with few effective therapies available. We repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa80156946ae3531f6b32f86aa53f52
https://escholarship.org/uc/item/7v07r0st
https://escholarship.org/uc/item/7v07r0st
Autor:
Bryce A. Kerlin, Bin Li, Junfeng Wang, Karin M.L. Gaensler, Yizhou Dong, Yimin Shi, Binbin Deng, Xiao Luo, Xu Tan, Amy L. Dunn, David W. McComb
Publikováno v:
Nano Letters. 15:8099-8107
Systemic delivery of mRNA-based therapeutics remains a challenging issue for preclinical and clinical studies. Here, we describe new lipid-like nanoparticles (TT-LLNs) developed through an orthogonal array design, which demonstrates improved delivery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e6c57566dd952cd800a35dff6288e4
https://doi.org/10.1021/acs.nanolett.5b03528
https://doi.org/10.1021/acs.nanolett.5b03528
Autor:
Margaret R. O'Donnell, Amy E. DeZern, H. Joachim Deeg, Virginia M. Klimek, Peter L. Greenberg, Rami S. Komrokji, Karin M.L. Gaensler, John M. Bennett, Clara D. Bloomfield, Carlos M. de Castro, Paul J. Shami, Guillermo Garcia-Manero, Lisa Kujawski, Daniel A. Pollyea, Peter Westervelt, Brady L. Stein, Olga Frankfurt, Bart L. Scott, Uma Borate, Amir T. Fathi, Courtney Smith, Richard Stone, Lori J. Maness, Dorothy A. Shead, David R. Head, Elizabeth A. Griffiths, Rafael Bejar, Benton Wheeler
Publikováno v:
Journal of the National Comprehensive Cancer Network. 13:261-272
The NCCN Guidelines for Myelodysplastic Syndromes (MDS) comprise a heterogeneous group of myeloid disorders with a highly variable disease course that depends largely on risk factors. Risk evaluation is therefore a critical component of decision-maki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25f9dd6815f0d47b24fdc7f0dfcfce6b
https://doi.org/10.6004/jnccn.2015.0038
https://doi.org/10.6004/jnccn.2015.0038