Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Karin M. Höld"'
Publikováno v:
Chemical Research in Toxicology. 14:589-595
Alpha- and beta-Thujones are active ingredients in the liqueur absinthe and in herbal medicines and seasonings for food and drinks. Our earlier study established that they are convulsants and have insecticidal activity, acting as noncompetitive block
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::923b41596f08a03b6171d179ad9be2cb
https://doi.org/10.1021/tx000242c
https://doi.org/10.1021/tx000242c
Publikováno v:
Journal of Agricultural and Food Chemistry. 49:1915-1921
Essential oils containing alpha- and beta-thujones are important herbal medicines and food additives. The thujone diastereomers are rapidly metabolized convulsants acting as noncompetitive blockers of the gamma-aminobutyric acid-gated chloride channe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::106f12cf4d5559cb13552e38e172e375
https://doi.org/10.1021/jf001445+
https://doi.org/10.1021/jf001445+
Publikováno v:
Journal of Analytical Toxicology. 20:345-349
Stanozolol is an anabolic androgenic steroid occasionally abused by athletes. A sensitive, specific, and reproducible method for the quantitative determination of stanozolol in hair has been developed. After the addition of stanozolol-d3 as the inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b780980ce6c53de792574bcc7c36b17b
https://doi.org/10.1093/jat/20.6.345
https://doi.org/10.1093/jat/20.6.345
Autor:
Douglas E. Rollins, Dennis V. Canfield, Dennis J. Crouch, Robert A. A. Maes, Diana G. Wilkins, Karin M. Höld
Publikováno v:
Journal of Mass Spectrometry. 31:1033-1038
A sensitive and specific method was developed for the determination of alprazolam and its major metabolite alpha-hydroxyalprazolam in plasma. After the addition of deuterium-labeled internal standards, plasma samples were buffered to pH 9 with 1 ml o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b2538523a85d02472cf42c0018b053f
https://doi.org/10.1002/(sici)1096-9888(199609)31:9<1033::aid-jms391>3.0.co
https://doi.org/10.1002/(sici)1096-9888(199609)31:9<1033::aid-jms391>3.0.co
Publikováno v:
Journal of Chromatographic Science. 34:13-19
An enantioselective gas chromatographic-mass spectrometric assay is developed for alprenolol and its metabolite, 4-hydroxy-alprenolol, in saliva and plasma. The procedure is based on a two-step derivatization technique with N-heptafluorobutyryl-l-pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f141839858693dd952dba2a10176e7e
https://doi.org/10.1093/chromsci/34.1.13
https://doi.org/10.1093/chromsci/34.1.13
Autor:
Dirk L. Ypey, Peter J. Nijweide, Arnoud van der Laarse, Karin M. Höld, Adam F. Weidema, Arie van der Plas, Jan H. Ravesloot
Publikováno v:
Journal of bone and mineral research, 7(2 S), S377-S387. Wiley-Blackwell
Embryonic chick bone cells express various types of ionic channels in their plasma membranes for as yet unresolved functions. Chick osteoclasts (OCL) have the richest spectrum of channel types. Specific for OCL is a K+ channel, which activates (opens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9e2cf1155504a348ef1048a7f92d964
https://doi.org/10.1002/jbmr.5650071404
https://doi.org/10.1002/jbmr.5650071404
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 32(4)
1. Hyssop oil is an important food additive and herbal medicine and the principal active ingredients are (-)-cis- and (-)-trans-3-pinanones. No information is available on their metabolism or specific mode of action. 2. The metabolites of cis- and tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7fc6189c3d16e29fe51f32af4a48ee
https://pubmed.ncbi.nlm.nih.gov/12028660
https://pubmed.ncbi.nlm.nih.gov/12028660
α-Thujone is the toxic agent in absinthe, a liqueur popular in the 19th and early 20th centuries that has adverse health effects. It is also the active ingredient of wormwood oil and some other herbal medicines and is reported to have antinociceptiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae26d15ae28ce13644219b5a842ffd51
https://europepmc.org/articles/PMC18101/
https://europepmc.org/articles/PMC18101/
Publikováno v:
Journal of analytical toxicology. 23(6)
Nandrolone and testosterone are anabolic androgenic steroids occasionally abused by athletes. A sensitive, specific, and reproducible gas chromatography-mass spectrometry method for the quantitative determination of nandrolone, testosterone, and thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652f074740230fd77366e086dc1ef754
https://pubmed.ncbi.nlm.nih.gov/10517545
https://pubmed.ncbi.nlm.nih.gov/10517545
Publikováno v:
Journal of analytical toxicology. 23(6)
A 10-week inpatient study was performed to evaluate cocaine, codeine, and metabolite disposition in biological matrices collected from volunteers. An initial report described drug disposition in plasma, sebum, and stratum corneum collected from five
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::513c6e53da1efdc6290486eb7951c98b
https://pubmed.ncbi.nlm.nih.gov/10517543
https://pubmed.ncbi.nlm.nih.gov/10517543