Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Karin M. Balss"'
Publikováno v:
Journal of Pharmaceutical Sciences. 110:3786-3793
Application of Raman spectroscopy as a T cell characterization tool supporting cell therapy drug product development has been evaluated. Statistically significant correlations between a set of Raman signals and established flow cytometry markers asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::722a6137e2fa6d599015ebe74d11f4b0
https://doi.org/10.1016/j.xphs.2021.08.005
https://doi.org/10.1016/j.xphs.2021.08.005
Publikováno v:
Biotechnology Progress. 36
The Food and Drug Administration (FDA) initiative of Process Analytical Technology (PAT) encourages the monitoring of biopharmaceutical manufacturing processes by innovative solutions. Raman spectroscopy and the chemometric modeling tool partial leas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d3f2eabf1275897ea034f8bfe665cd
https://doi.org/10.1002/btpr.2977
https://doi.org/10.1002/btpr.2977
Autor:
Carl Rafferty, Karin M. Balss, Dan Hill, Olav Lyngberg, Jim O'Mahony, Caitlin O’Mahony-Hartnett, Rosemary Rea, Barbara Burgoyne, Eugene Schaefer
Publikováno v:
Bioprocess and biosystems engineering. 43(8)
Multiple process analytical technology (PAT) tools are now being applied in tandem for cell culture. Research presented used two in-line probes, capacitance for a dynamic feeding strategy and Raman spectroscopy for real-time monitoring. Data collecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de30d3dc1ba5c6cd48bd992df54b308
https://pubmed.ncbi.nlm.nih.gov/32303846
https://pubmed.ncbi.nlm.nih.gov/32303846
Autor:
David C. Latshaw, Carl Rafferty, Barbara Burgoyne, Rosemary Rea, Jim O'Mahony, Karin M. Balss
Publikováno v:
Biotechnology and bioengineeringREFERENCES. 117(1)
Raman spectroscopy is a robust, well-established tool utilized for measuring important cell culture process variables for example, feed, metabolites, and biomass in real-time. This study further expands the functionality of in-line Raman spectroscopy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e8e745953816c74fafe549a1bf9c8d
https://pubmed.ncbi.nlm.nih.gov/31631327
https://pubmed.ncbi.nlm.nih.gov/31631327
Publikováno v:
Langmuir. 28:8238-8243
Drug release from and coating morphology on a CYPHER sirolimus-eluting coronary stent (SES) during in vitro elution were studied by correlated confocal Raman and atomic force microscopy (CRM and AFM, respectively). Chemical surface and subsurface map
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::269687074c383b55008cddd26e737a2d
https://doi.org/10.1021/la300808z
https://doi.org/10.1021/la300808z
Autor:
Kurt Wolf, Juan Meng, Karin M. Balss, Zong Zong, Argjenta Orana, Nima Rahbar, Cynthia A. Maryanoff, Wole Soboyejo, George Papandreou
Publikováno v:
Journal of Biomedical Materials Research Part A. :272-281
An atomic force microscopy (AFM) method was developed to quantify the adhesion forces between and cohesive forces within the layers of a drug-eluting stent (DES). Surface pairs representing both the individual components and the complete chemistry of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::917db096869e2c5c8540ed78a5f911fe
https://doi.org/10.1002/jbm.a.31860
https://doi.org/10.1002/jbm.a.31860
Autor:
Barbara J. Jones, Stacey J. Hoebel, Constantin D. Malliaris, Karin M. Balss, Matthew S. Munson, David J. Ross, Wyatt N. Vreeland
Publikováno v:
Analytical Chemistry. 78:7186-7190
Temperature gradient focusing (TGF) is a recently developed technique for the simultaneous concentration and electrophoretic separation of ionic analytes in microfluidic channels. One drawback to TGF as it has previously been described is the limited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef43e8889efa1ebfbf2c760c89c403b
https://doi.org/10.1021/ac060934r
https://doi.org/10.1021/ac060934r
Publikováno v:
Langmuir. 21:10459-10467
Fast transient microboiling has been characterized on modified gold microheaters using a novel laser strobe microscopy technique. Microheater surfaces of different hydrophobicity were prepared using self-assembled monolayers of hexadecane thiol (hydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::846530cfe86231c8ce8c49340d42036c
https://doi.org/10.1021/la040137t
https://doi.org/10.1021/la040137t
Publikováno v:
Journal of the American Chemical Society. 126:13474-13479
Two types of DNA hybridization assays are demonstrated with temperature gradient focusing (TGF) and peptide nucleic acids (PNAs). In TGF, the application of a controlled temperature gradient along the length of a microchannel filled with an appropria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16cd6de0882e9c1a3c0c6e0ae4416be4
https://doi.org/10.1021/ja030667w
https://doi.org/10.1021/ja030667w
Publikováno v:
The Journal of Physical Chemistry B. 107:994-1000
Surface-enhanced Raman spectroscopy (SERS) was employed to map the composition of electrochemically generated gradients in aromatic thiols on Au electrodes. Two commonly used substrates, electrochemically roughened (ORC) and metal film over nanospher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9378c199b36e5e1f3b1b887b21755157
https://doi.org/10.1021/jp021875y
https://doi.org/10.1021/jp021875y