Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Karin M E Andersson"'
Autor:
Venkataragavan Chandrasekaran, Karin M. E. Andersson, Malin Erlandsson, Shuxiang Li, Torbjörn Nur Olsson, Maria-Jose Garcia-Bonete, Eric Malmhäll-Bah, Pegah Johansson, Gergely Katona, Maria I. Bokarewa
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-24 (2024)
Abstract Background Bivalent regions of chromatin (BvCR) are characterized by trimethylated lysine 4 (H3K4me3) and lysine 27 on histone H3 (H3K27me3) deposition which aid gene expression control during cell differentiation. The role of BvCR in post-t
Externí odkaz:
https://doaj.org/article/607961b2191a4331a9a9f4b3e13e88db
Autor:
Malin C. Erlandsson, Seval Erdogan, Caroline Wasén, Karin M. E. Andersson, Sofia T. Silfverswärd, Rille Pullerits, Mats Bemark, Maria I. Bokarewa
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
ObjectiveInsulin-like growth factor 1 receptor (IGF1R) acts at the crossroad between immunity and cancer, being an attractive therapeutic target in these areas. IGF1R is broadly expressed by antigen-presenting cells (APC). Using mice immunised with t
Externí odkaz:
https://doaj.org/article/71f464cd5e29458a8b15e6ffe7f297e7
Autor:
Venkataragavan Chandrasekaran, Nina Oparina, Maria-Jose Garcia-Bonete, Caroline Wasén, Malin C. Erlandsson, Eric Malmhäll-Bah, Karin M. E. Andersson, Maja Jensen, Sofia T. Silfverswärd, Gergely Katona, Maria I. Bokarewa
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Proper physiological functioning of any cell type requires ordered chromatin organization. In this context, cohesin complex performs important functions preventing premature separation of sister chromatids after DNA replication. In partnership with C
Externí odkaz:
https://doaj.org/article/1022e5b4095b48e990308bb6466e0acc
Autor:
Mitra Nadali, Lovisa Lyngfelt, Malin C. Erlandsson, Sofia Töyrä Silfverswärd, Karin M. E. Andersson, Maria I. Bokarewa, Rille Pullerits
Publikováno v:
Frontiers in Medicine, Vol 7 (2021)
Background: Cardiovascular disease (CVD) causes premature mortality in rheumatoid arthritis (RA). Levels of soluble (s)RAGE change with aging, hypertension and hypercholesterolemia. We assessed whether sRAGE was associated with increased risk of CVD
Externí odkaz:
https://doaj.org/article/068622a39e044390a2b41ed948ad9f81
Autor:
Caroline Wasén, Caroline Ospelt, Alessandro Camponeschi, Malin C. Erlandsson, Karin M. E. Andersson, Sofia Töyrä Silfverswärd, Steffen Gay, Maria I. Bokarewa
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Objective: Smoking suppresses PD-1 expression in patients with rheumatoid arthritis (RA). In this study, we assess if smoking changed the epigenetic control over CD8+ T cell memory formation through a microRNA (miR) dependent mechanism.Methods: Pheno
Externí odkaz:
https://doaj.org/article/94d6b351ce38470a962b6ef898ad58c8
Autor:
Malin C, Erlandsson, Karin M E, Andersson, Nina Y, Oparina, Venkataragavan, Chandrasekaran, Tibor, Saghy, Anastasios, Damdimopoulos, Maria-Jose, Garcia-Bonete, Zakaria, Einbeigi, Sofia T, Silfverswärd, Marcela, Pekna, Gergely, Katona, Maria I, Bokarewa
Publikováno v:
iScience. 25(12)
In this study, we explore the role of nuclear survivin in maintaining the effector phenotype of IFNγ-producing T cells acting through the transcriptional control of glucose utilization. High expression of survivin in CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7efcad7427598061d185a47c255852a1
https://pubmed.ncbi.nlm.nih.gov/36425763
https://pubmed.ncbi.nlm.nih.gov/36425763
Autor:
Howard L. Weiner, Maria I. Bokarewa, Gopal Murugaiyan, Karin M. E. Andersson, Dan Hu, Minh C. Pham, Gabriela M. Molica, Nathalie Pochet, Brian C. Healy, Vijay K. Kuchroo, Emily C. Tjon
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Identifying signaling pathways contributing to resistance to anti-TNF therapy in rheumatoid arthritis is crucial for the development of new therapeutic strategies for refractory rheumatoid arthritis. Th17 cells, a subset of proinflammato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d2a6d1e1e2be17dfc66da75fb2928d
https://doi.org/10.1073/pnas.2007935117
https://doi.org/10.1073/pnas.2007935117
Autor:
Carolina, Larsson, Karin M E, Andersson, Mitra, Nadali, Sofia T, Silfverswärd, Maria I, Bokarewa, Malin C, Erlandsson
Publikováno v:
Clinical and Experimental Rheumatology.
MicroRNAs (miRs) are non-translated RNA sequences that elicit negative control over protein expression. The adipose tissue (AT) is considered the major producer of miRs and inflammatory interleukin 6 (IL-6). This study aims to investigate the relatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c85ea66a9290310dfcfbe4f7d19002a
https://doi.org/10.55563/clinexprheumatol/f4vlvt
https://doi.org/10.55563/clinexprheumatol/f4vlvt
Autor:
Marcela Pekna, Anastasios E. Damdimopoulos, N. Oparina, Malin C. Erlandsson, Venkataragavan Chandrasekaran, Sofia Töyrä Silfverswärd, Maria Bokarewa, Karin M. E. Andersson, Maria-Jose Garcia-Bonete, Gergely Katona, Zakaria Einbeigi
Interferon-gamma (IFNγ) producing T cells develop metabolic adaptation required for their effector functions in tumour biology, autoimmunity and antiviral defence.Using sorted CD4+cells we demonstrated that glycolytic switch and high glucose uptake
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ce7fdb5a74d0d92438fbda2f59cfaa6
https://doi.org/10.1101/2021.10.05.463166
https://doi.org/10.1101/2021.10.05.463166
Autor:
Mitra Nadali, Rille Pullerits, Karin M. E. Andersson, Sofia Töyrä Silfverswärd, Malin C. Erlandsson, Maria I. Bokarewa
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 11, p 2410 (2017)
Despite the predominance of female patients and uncommon obesity, rheumatoid arthritis (RA) is tightly connected to increased cardiovascular morbidity. The aim of this study was to investigate transcriptional activity in the subcutaneous white adipos
Externí odkaz:
https://doaj.org/article/c59cdf9efd2c46809f468f19a10d0210