Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Karin Lykke‐Hartmann"'
Autor:
Julie Feld Madsen, Emil Hagen Ernst, Mahboobeh Amoushahi, Margit Dueholm, Erik Ernst, Karin Lykke-Hartmann
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract AMPK is a well-known energy sensor regulating cellular metabolism. Metabolic disorders such as obesity and diabetes are considered detrimental factors that reduce fecundity. Here, we show that pharmacologically induced in vitro activation (b
Externí odkaz:
https://doaj.org/article/4064d758b4ff452a8687fa3d488a5a3a
Autor:
Nico A. Jansen, Chelsey Linnenbank, Maarten Schenke, Rob A. Voskuyl, Maria S. Jorge, Georgii Krivoshein, Cor Breukel, Margot M. Linssen, Jill W.C. Claassens, Conny Brouwers, Sandra H. van Heiningen, Anders Heuck, Karin Lykke-Hartmann, Else A. Tolner, Arn M.J.M. van den Maagdenberg
Publikováno v:
Neurobiology of Disease, Vol 202, Iss , Pp 106714- (2024)
The mechanisms of initiation of spreading depolarization (SD) are understudied due to a paucity of disease models with spontaneously occurring events. We here present a novel mouse model of familial hemiplegic migraine type 2 (FHM2), expressing the m
Externí odkaz:
https://doaj.org/article/06ea3f35c9c3417aa35517e998fb1500
Autor:
Christian Staehr, Palle Duun Rohde, Nikolaj Thure Krarup, Steffen Ringgaard, Christoffer Laustsen, Jacob Johnsen, Rikke Nielsen, Hans Christian Beck, Jens Preben Morth, Karin Lykke‐Hartmann, Nichlas Riise Jespersen, Denis Abramochkin, Mette Nyegaard, Hans Erik Bøtker, Christian Aalkjaer, Vladimir Matchkov
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 7 (2022)
Background Mutations in ATP1A2 gene encoding the Na,K‐ATPase α2 isoform are associated with familial hemiplegic migraine type 2. Migraine with aura is a known risk factor for heart disease. The Na,K‐ATPase is important for cardiac function, but
Externí odkaz:
https://doaj.org/article/82227bc414f6440f9965cdb15cfd02ed
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/55f1df544af04bf8a6728613b1324bd0
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Women with cancer and low ovarian reserves face serious challenges in infertility treatment. Ovarian tissue cryopreservation is currently used for such patients to preserve fertility. One major challenge is the activation of dormant ovarian follicles
Externí odkaz:
https://doaj.org/article/115f1795f2054611b5defe11e3894f71
Autor:
Ditte Gry Ellman, Toke Jost Isaksen, Minna Christiansen Lund, Safinaz Dursun, Martin Wirenfeldt, Louise Helskov Jørgensen, Karin Lykke-Hartmann, Kate Lykke Lambertsen
Publikováno v:
BMC Neuroscience, Vol 18, Iss 1, Pp 1-13 (2017)
Abstract Background The Na+/K+-ATPases are transmembrane ion pumps important for maintenance of ion gradients across the plasma membrane that serve to support multiple cellular functions, such as membrane potentials, regulation of cellular volume and
Externí odkaz:
https://doaj.org/article/0c1c61b682c14ec2aa8d3d01a6b081ee
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Externí odkaz:
https://doaj.org/article/bac00620616b40fda22b1f0d5770e839
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 6 (2018)
Bidirectional cross talk between granulosa cells and oocytes is known to be important in all stages of mammalian follicular development. Insulin-like growth factor (IGF) signaling is a prominent candidate to be involved in the activation of primordia
Externí odkaz:
https://doaj.org/article/a620903c89fe40fe8d504c8b98e3b02d
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 6 (2018)
Emerging evidence indicated that many long non-coding (lnc)RNAs function in multiple biological processes and dysregulation of their expression can cause diseases. Most regulatory lncRNAs interact with biological macromolecules such as DNA, RNA, and
Externí odkaz:
https://doaj.org/article/bdf5a1f367ea426bb680f11e81a7ffb1
Autor:
Trine Strandgaard, Solveig Foder, Anders Heuck, Erik Ernst, Morten S. Nielsen, Karin Lykke-Hartmann
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 5 (2017)
Folates have been shown to play a crucial role for proper development of the embryo as folate deficiency has been associated with reduced developmental capacity such as increased risk of fetal neural tube defects and spontanous abortion. Transcripts
Externí odkaz:
https://doaj.org/article/9395f2ce31df4b9aaf828ab19d6c8bce