Zobrazeno 1 - 10
of 583
pro vyhledávání: '"Karin Klingel"'
Autor:
Guglielmo Gioia, Lore Schrutka, Joanna Jozwiak‐Nozdrzykowska, Karl‐Patrik Kresoja, Hilka Gunold, Karin Klingel, Holger Thiele, Diana Bonderman, Philipp Lurz, Karl‐Philipp Rommel
Publikováno v:
ESC Heart Failure, Vol 11, Iss 4, Pp 2172-2181 (2024)
Abstract Aims Transthyretin ‘wild‐type’ amyloid cardiomyopathy (ATTRwt‐CM) is a differential diagnosis of heart failure with preserved ejection fraction (HFpEF). The clinical work‐up for ATTRwt‐CM is challenging. Considering a combination
Externí odkaz:
https://doaj.org/article/0250ae9b38144e0a80beed283cd3a91b
Autor:
Leslie Elsner, Lisanne Heimann, Anja Geisler, Babette Dieringer, Klaus-Peter Knoch, Luisa Hinze, Karin Klingel, Michel Solimena, Jens Kurreck, Henry Fechner
Publikováno v:
Biological Procedures Online, Vol 26, Iss 1, Pp 1-16 (2024)
Abstract Background The efficacy of oncolytic viruses (OV) in cancer treatment depends on their ability to successfully infect and destroy tumor cells. However, patients’ tumors vary, and in the case of individual insensitivity to an OV, therapeuti
Externí odkaz:
https://doaj.org/article/12073503249b4b00bb4d7853be5b2933
Autor:
Isabel Mattig, Tilman Steudel, Karin Klingel, Gina Barzen, David Frumkin, Sebastian Spethmann, Elena Romero Dorta, Karl Stangl, Bettina Heidecker, Ulf Landmesser, Fabian Knebel, Sima Canaan-Kühl, Katrin Hahn, Anna Brand
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Echocardiographic differentiation of cardiac amyloidosis (CA) and Fabry disease (FD) is often challenging using standard echocardiographic parameters. We retrospectively analyzed the diagnostic accuracy of right heart and left atrial strain
Externí odkaz:
https://doaj.org/article/7dc75468acb04b7eaf31c2724c076ab3
Autor:
Lisann Pelzl, Sabrina Mantino, Martina Sauter, Tatiana Manuylova, Ulrich Vogel, Karin Klingel
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1909 (2024)
Background: This study aims to evaluate the role of parvovirus B19 (B19V) in the pathogenesis of myocarditis in a paediatric population, including post-mortem samples from two children. Methods: From 2004 to 2023, endomyocardial biopsies (EMBs) from
Externí odkaz:
https://doaj.org/article/42387756c11b4bd1b43c3526bbde8d8d
Autor:
Nicolas Musigk, Phillip Suwalski, Ainoosh Golpour, DeLisa Fairweather, Karin Klingel, Pilar Martin, Andrea Frustaci, Leslie T. Cooper, Thomas F. Lüscher, Ulf Landmesser, Bettina Heidecker
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Infiltration of the myocardium with various cell types, cytokines and chemokines plays a crucial role in the pathogenesis of cardiomyopathies including inflammatory cardiomyopathies and myocarditis. A more comprehensive understanding of the precise i
Externí odkaz:
https://doaj.org/article/19f149fe22634891930d73198fb393ff
Autor:
Richard I. Lewis, Katharina Seuthe, Simon Lennartz, Jan-Phillip Weber, Nicole Kreuzberg, Karin Klingel, Paul J. Bröckelmann
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
IntroductionImmune checkpoint inhibitors have advanced the outcomes of many different types of cancer. A rare but extraordinarily severe complication of these agents resembles immune checkpoint inhibitor-related myocarditis, which typically occurs wi
Externí odkaz:
https://doaj.org/article/37821c24b44c4826ab4d27f14342b0c2
Autor:
Anja Geisler, Babette Dieringer, Leslie Elsner, Karin Klingel, Robert Klopfleisch, Hans-Peter Vornlocher, Jens Kurreck, Henry Fechner
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 923-936 (2023)
RNA interference has demonstrated its potential as an antiviral therapy for treatment of human adenovirus (hAd) infections. The only existing viral vector-based system for delivery of anti-adenoviral artificial microRNAs available for in vivo use, ho
Externí odkaz:
https://doaj.org/article/8f857671448d4f67b3c18507d9e19145
Autor:
Mara Stellato, Matthias Dewenter, Michal Rudnik, Amela Hukara, Çagla Özsoy, Florian Renoux, Elena Pachera, Felix Gantenbein, Petra Seebeck, Siim Uhtjaerv, Elena Osto, Daniel Razansky, Karin Klingel, Joerg Henes, Oliver Distler, Przemysław Błyszczuk, Gabriela Kania
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
The role of the transcription factor Fosl-2 in promoting myocardial fibrosis, arrhythmias and aberrant response to stress under immunofibrotic conditions is described using an in vivo mouse model and human cardiac fibroblasts.
Externí odkaz:
https://doaj.org/article/ff374a3b12b64c5493c7766311f21e33
Autor:
Mintje Bohné, Sebastian Bohnen, Hans-Christian Voigt, Hendrik van der Schalk, Da-Un Chung, Stephan Willems, Karin Klingel, Dietmar Kivelitz, Edda Bahlmann
Publikováno v:
BMC Cardiovascular Disorders, Vol 22, Iss 1, Pp 1-7 (2022)
Abstract Background Loeffler-endocarditis (LE) is considered a chronic restrictive cardiomyopathy and manifestation of eosinophilic myocarditis characterized by eosinophilic infiltration. LE is a rare underdiagnosed disease and associated with high m
Externí odkaz:
https://doaj.org/article/a15f4a5cd0ee4ec4bd1ce41ef4b48f55
Autor:
Heiner Latus, Ramona Raap, Karin Klingel, Christoph Happel, Axel Moysich, Markus Khalil, Gunter Kerst, Jakob Milla, Susanne Skrzypek, Josef Thul, Christian Jux, Dietmar Schranz, Christian Apitz
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 13 (2023)
Background In patients after heart transplantation, systemic arterial hypertension and enhanced central aortic stiffness contribute to increased ventricular afterload, which might lead to graft dysfunction. The aim of our study was to characterize sy
Externí odkaz:
https://doaj.org/article/f15beb5a0448494c9f11811ac416ec87