Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Karin Kaiserova"'
Publikováno v:
Journal of Biological Chemistry. 283:9101-9112
Aldose reductase (AR) catalyzes the reduction of several aldehydes ranging from lipid peroxidation products to glucose. The activity of AR is increased in the ischemic heart due to oxidation of its cysteine residues, but the underlying mechanisms rem
Autor:
Jian Cai, Sanjay K. Srivastava, Xian Liang Tang, Aruni Bhatnagar, Karin Kaiserova, Joseph David Hoetker, Sunday O. Awe
Publikováno v:
Journal of Biological Chemistry. 281:15110-15120
Aldose reductase (AR) reduces cytotoxic aldehydes and glutathione conjugates of aldehydes derived from lipid peroxidation. Its inhibition has been shown to increase oxidative injury and abolish the late phase of ischemic preconditioning. However, the
Autor:
Sanjay K. Srivastava, Stephen S. Chung, Aruni Bhatnagar, Greg Hunt, Oleg A. Barski, Karin Kaiserova, Buddhadeb Dawn, Elena Vladykovskaya, Matthew Spite, J. Mark Petrash
Publikováno v:
Circulation research. 105(8)
RATIONALE: Atherosclerotic lesion formation is associated with the accumulation of oxidized lipids. Products of lipid oxidation, particularly aldehydes, stimulate cytokine production and enhance monocyte adhesion; however, their contribution to ather
Publikováno v:
Journal of Molecular and Cellular Cardiology. 42:S179